Protein Alignment CG31793 and Abcc4

DIOPT Version :10

• Sequence 1: NP_609930.4
• Gene: CG31793 / 326161
• FlyBaseID: FBgn0051793
• Length: 1307
• Species: Drosophila melanogaster
• Sequence 2: NP_001028508.2
• Gene: Abcc4 / 239273
• MGIID: 2443111
• Length: 1325
• Species: Mus musculus
• Alignment Length: 1332
• Identity: 587/1332 - (44%)
• Similarity: 838/1332 - (62%)
• Gaps: 69/1332 - (5%)

  Fly     4 SKLPPNPRESAGILSSLMFCFALPILFKGRKQTLQPTDLYKTLNEHEAASLGDEFFQGWEDEVAR 68
            :::.|||.:.|.:.|.:.|.:..|:...|.|:.|:..|::..|.|..:..||:|..:.|:.|:.|
Mouse     6 TEVKPNPLQDANLCSRVFFWWLNPLFKTGHKRRLEEDDMFSVLPEDRSKHLGEELQRYWDKELLR 70

  Fly    69 CRRKGDSGRKPSVLRVIGRVFGWR--LIMSGITIAALELGTRATVPLLLAGLISEFSEHGNGHS- 130
            .::  || ||||:.:.|.:.: |:  ||:...|:  :|.|||...||.|..:|..|.::....|
Mouse    71 AKK--DS-RKPSLTKAIIKCY-WKSYLILGIFTL--IEEGTRVVQPLFLGKIIEYFEKYDPDDSV 129

  Fly   131 --YNAQIYAVLLIACILASVLLTHPYMMGMMHLAMKMRVAVSSAIYRKALRLSRTSLGGTTTGQV 193
              :.|..||.:|..|.|...:|.|.|...:....|::|||:...|||||||||.:::|.|||||:
Mouse   130 ALHTAYGYAAVLSMCTLILAILHHLYFYHVQCAGMRLRVAMCHMIYRKALRLSNSAMGKTTTGQI 194

  Fly   194 VNLLSNDLNRFDRCLIHFHFLWLGPLELLIASYFLYEQIGMASFYGISILVLYLPLQTYLSRVTS 258
            |||||||:|:||:..|..||||.|||:.:..:..|:.:||::...|:::||:.||||:.:.::.|
Mouse   195 VNLLSNDVNKFDQVTIFLHFLWAGPLQAIAVTVLLWVEIGISCLAGLAVLVILLPLQSCIGKLFS 259

  Fly   259 KLRLQTALRTDQRVRMMNEIISGIQVIKMYTWERPFGKLIGQMRRSEMSSIRQMNLLRGILLSFE 323
            .||.:||..||.|:|.|||:|:|:::||||.||:.|..||..:|:.|:|.|...:.|||:.::..
Mouse   260 SLRSKTAAFTDARIRTMNEVITGMRIIKMYAWEKSFADLIANLRKKEISKILGSSYLRGMNMASF 324

  Fly   324 ITLGRIAIFVSLLGFVLGGGELTAERAFCVTAFYNILRRTVSKFFPSGMSQFAELLVSMRRITNF 388
            ....::.:||:...:||.|.|:||...|.....|..:|.||:.||||.:.:.:|.:||:|||.||
Mouse   325 FIANKVILFVTFTSYVLLGNEITASHVFVAMTLYGAVRLTVTLFFPSAIERGSEAIVSIRRIKNF 389

  Fly   389 MMREEANVIDMSERRDEKAEEEQHLLKEVEKRSYPVGIGKEPDTLVEIKALRARWGQEQHDLVLN 453
            ::            .||..:.:.|:..:          ||   .:|.::...|.|.:......|.
Mouse   390 LL------------LDELPQRKAHVPSD----------GK---AIVHVQDFTAFWDKALDSPTLQ 429

  Fly   454 NVNMSLRRGQLVAVIGPVGSGKSSLIQAILGELPPESGSVQVSGKYSYASQEPWLFNASVRDNIL 518
            .::...|.|:|:||:||||:|||||:.|:||||||.||.|.|.|:.:|.||:||:|:.:||.|||
Mouse   430 GLSFIARPGELLAVVGPVGAGKSSLLSAVLGELPPASGLVSVHGRIAYVSQQPWVFSGTVRSNIL 494

  Fly   519 FGLPMDKQRYRTVLKRCALERDLELLH-GDGTIVGERGASLSGGQRARICLARAVYRRADVYLLD 582
            ||...:|:||..|:|.|||::||:||. ||.|::|:|||:|||||:||:.||||||:.||:||||
Mouse   495 FGKKYEKERYEKVIKACALKKDLQLLEDGDLTVIGDRGATLSGGQKARVNLARAVYQDADIYLLD 559

  Fly   583 DPLSAVDTHVGRHLFDECMRGFLGKQLVILVTHQLQFLEDADLIVIMDKGHVSACGTYEEMLKSG 647
            |||||||..||:|||..|:...|.:::.||||||||:|:.|..|:|:..|.:...|||.|.||||
Mouse   560 DPLSAVDAEVGKHLFQLCICQALHEKITILVTHQLQYLKAASHILILKDGEMVQKGTYTEFLKSG 624

  Fly   648 QDFAQLLVESTQNSGGGDEIITSPNL----SRQSSALSTKSSNGSSSSLESMVE--KEKPKPSAV 706
            .||..||.:..:.:    |..|:|..    .|..|..|..|...|..||:....  ::.....||
Mouse   625 VDFGSLLKKENEEA----EPSTAPGTPTLRKRTFSEASIWSQQSSRPSLKDGAPEGQDAENTQAV 685

  Fly   707 SSQESRSGGQIGLSMYKKYFGAGCGVLVFVVLIMLCIGTQILASGGDYFLSYW------VKNTAS 765
            ..:||||.|:||...||.||.||......:.|::|.:..|:.....|::||:|      :.||.:
Mouse   686 QPEESRSEGRIGFKAYKNYFSAGASWFFIIFLVLLNMVGQVFYVLQDWWLSHWANKQGALNNTRN 750

  Fly   766 SS-----TLDIYYFTAINVGL----VICALLRTLLFFNITMHSSTELHNTMFQGLSRTALYFFHT 821
            ::     |||:.::..|..||    |:..:.|:||.|.|.:::|..|||.||:.:.:..:.||..
Mouse   751 ANGNITETLDLSWYLGIYAGLTAVTVLFGIARSLLVFYILVNASQTLHNRMFESILKAPVLFFDR 815

  Fly   822 NPSGRILNRFANDLGQVDEVMPAVMLDCIQIFLTLTGIICVLCVTNPWYLINTFAMMLAFYYWRD 886
            ||.|||||||:.|:|.:|:::|...||.||..|.:..:|.|.....||.||....:.:.|...|.
Mouse   816 NPIGRILNRFSKDIGHMDDLLPLTFLDFIQTLLLVVSVIAVAAAVIPWILIPLVPLSVVFLVLRR 880

  Fly   887 FYLKTSRDVKRLEAVARSPMYSHFSATLVGLPTIRAMGAQQTLIGQYDNYQDLHSSGYYTFVSTS 951
            ::|:|||||||||:..|||::||.|::|.||.||||..|::.....:|.:|||||..::.|::||
Mouse   881 YFLETSRDVKRLESTTRSPVFSHLSSSLQGLWTIRAYKAEERCQELFDAHQDLHSEAWFLFLTTS 945

  Fly   952 RAFGYYLDLFCVAYVISVILHNFFNPPLHNAGQIGLAITQALGMTGMVQWGMRQSAELENAMTSV 1016
            |.|...||..|..:||.|...:.......||||:|||::.||.:.||.||.:|||||:||.|.||
Mouse   946 RWFAVRLDAICAIFVIVVAFGSLVLAKTLNAGQVGLALSYALTLMGMFQWSVRQSAEVENMMISV 1010

  Fly  1017 ERVLEYKDLDPEGDFNSPAEKQPPKSWPKEGKLVTKDLSLRYEPDTNSPCVLKGLSFTIQPMEKV 1081
            |||:||.||:.|..:.  .:|:||..||.||.:|..:::..|..|  .|.|||.|:..|:..|||
Mouse  1011 ERVIEYTDLEKEAPWE--CKKRPPPGWPHEGVIVFDNVNFTYSLD--GPLVLKHLTALIKSREKV 1071

  Fly  1082 GIVGRTGAGKSSLINALFRLSYNDGAILIDSLDTNDIGLHDLRSKISIIPQEPVLFSGTMRYNLD 1146
            ||||||||||||||:||||||..:|.|.||.:.|.:|||||||.|:||||||||||:||||.|||
Mouse  1072 GIVGRTGAGKSSLISALFRLSEPEGKIWIDKILTTEIGLHDLRKKMSIIPQEPVLFTGTMRKNLD 1136

  Fly  1147 PFEQYPDDKLWKALEDVHLKEEISELPSGLQSIISEGGTNFSVGQRQLVCLARAILRENRILVMD 1211
            ||.::.|::||:|||:|.|||.|.:||..:.:.::|.|:|||||||||||||||||:.||||::|
Mouse  1137 PFNEHTDEELWRALEEVQLKEAIEDLPGKMDTELAESGSNFSVGQRQLVCLARAILKNNRILIID 1201

  Fly  1212 EATANVDPQTDALIQATIRNKFKDCTVLTIAHRLNTIMDSDKVLVMDAGHVVEFGSPYELLTASK 1276
            ||||||||:||.|||..||.||..|||||||||||||:||||::|:|:|.:.|:..||.|| .:.
Mouse  1202 EATANVDPRTDELIQQKIREKFAQCTVLTIAHRLNTIIDSDKIMVLDSGRLKEYDEPYVLL-QNP 1265

  Fly  1277 AKVFHGMVMQTGKASFDHLLKVAENT--KQNH 1306
            ..:|:.||.|.||.....|.:.|:..  ::|:
Mouse  1266 ESLFYKMVQQLGKGEAAALTETAKQVYFRRNY 1297

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31793	NP_609930.4	PLN03130	10..1305	CDD:215595	584/1323 (44%)
Abcc4	NP_001028508.2	PLN03130	12..1284	CDD:215595	582/1311 (44%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	657..690		7/32 (22%)
		PDZ-binding. /evidence=ECO:0000250|UniProtKB:O15439	1322..1325