Protein Alignment CG31793 and mrp-5

DIOPT Version :10

• Sequence 1: NP_609930.4
• Gene: CG31793 / 326161
• FlyBaseID: FBgn0051793
• Length: 1307
• Species: Drosophila melanogaster
• Sequence 2: NP_510479.1
• Gene: mrp-5 / 181587
• WormBaseID: WBGene00003411
• Length: 1427
• Species: Caenorhabditis elegans
• Alignment Length: 1330
• Identity: 406/1330 - (30%)
• Similarity: 665/1330 - (50%)
• Gaps: 132/1330 - (9%)

  Fly    12 ESAGILSSLMFCFALPILFKGRKQTLQPTDLYKTLNEHEAASLGDEFFQG-----------WEDE 65
            :.||:.|.:.:.:..|.|::..:..|....::           |..|:..           ||||
 Worm    71 DDAGLFSFVTYSWVFPYLYQAVRGKLDRNQVW-----------GCSFYDSCGLNMARLEVLWEDE 124

  Fly    66 VARCRRKGDSGRKPSVLRVIGRVFGWRLIMS-GITIAAL---ELGTRATVPLLLAGLISEFSEHG 126
                  |..:.:.||:.:||.|....||..| .:....|   .:|....:..|:|     |:|:.
 Worm   125 ------KKANAKSPSLFKVIYRFISTRLWFSCAVFFFCLIFGFIGPTCFIRRLIA-----FAENP 178

  Fly   127 NGHSYNAQIYA--VLLIACI----LASVLLTHPYMMGMMHLAMKMRVAVSSAIYRKALRLSRTSL 185
            .....:..:|:  :.|:|.|    .|.||.............:::|.||.:.:|:..  |:...|
 Worm   179 ERDEQSRIVYSYGIALVAAISVVEFARVLSYGATWAVSYRTGIRVRGAVLALLYKNV--LNSKDL 241

  Fly   186 GGTTTGQVVNLLSNDLNRFDRCLIHFHFLWLGPLELLIASYFLYEQIGMASFYGISILVLYLPLQ 250
            .|.|...|:|:.:||..|....:.....:.:|||.|:....:|...||..|..||.:..::..:|
 Worm   242 CGKTESDVINIFANDGQRLFDAVTFAPLVLVGPLVLVGGIGYLLMVIGRWSLLGILVFFVFDVIQ 306

  Fly   251 TYLSRVTSKLRLQTALRTDQRVRMMNEIISGIQVIKMYTWERPFGKLIGQMRRSEMSSIRQMNLL 315
            ..|.:.....|....::|::|:.||.|||..|:::||..||:.|...|.|.|:.|...||:....
 Worm   307 FGLGKSMVACRNLAIVKTEKRISMMAEIIKYIRIVKMNGWEQIFSAKIDQFRKEEKVQIRKSGYA 371

  Fly   316 RGILLSFEITLGRIAIFVSLLGFVLGGGELTAERAFCVTAFYNILRRTVSKFFPSGMSQFAELLV 380
            :.:.::....:..:|..::.:|.||.|.:|.|..||.....|.::...: :..|.|....||.:|
 Worm   372 QSLAIACGPVVPVVAAILTFVGVVLAGNDLLASDAFSAITVYFVMLFGI-RMIPYGSRYLAEAVV 435

  Fly   381 SMRRITNFMMREEANVIDMSERRDEKAEEEQHLLKEVEKRSY---------PVGIGKEPD----T 432
            :||||..:::.|:.....::...|        ::.:.:..:|         ||...|||.    .
 Worm   436 AMRRIQEYLLLEQYAPYPVTNAED--------VVLDCQGATYTYQPKAAKAPVDETKEPTENEVI 492

  Fly   433 LVEIKALRARWGQEQHDLVLNNVNMSLRRGQLVAVIGPVGSGKSSLIQAILGELPPESGSVQVSG 497
            :||.......:.:           :|::||:.:||||.||.|||::::||.|.:.....::.|..
 Worm   493 VVETPVFTCSFDK-----------LSIKRGEHIAVIGAVGCGKSAILKAISGHMFTTDDALSVDR 546

  Fly   498 KYS-YASQEPWLFNASVRDNILFGLPMDKQRYRTVLKRCALERDLELLH-GDGTIVGERGASLSG 560
            ..: |..|:.|:||.:|:||||||..|:.:||...:..|.|..||..|. ||.|.||||||:|||
 Worm   547 SQTVYVPQKAWIFNGTVQDNILFGDKMNSERYYKAVNGCQLTEDLTTLSVGDRTEVGERGATLSG 611

  Fly   561 GQRARICLARAVYRRADVYLLDDPLSAVDTHVGRHLFDECMRGFLGKQLVILVTHQLQFLEDADL 625
            ||:||:.|||||::..::||.||..:::|..|...:.:|.::..|.|:.:::||:.::.|...|.
 Worm   612 GQKARVALARAVFQTKNLYLFDDIFASLDKKVANKIHEEIIQKLLKKKALMMVTNNMELLHHFDR 676

  Fly   626 IVIMDKGHVSACGTYEEMLKSGQDFAQLL--VESTQNSGGGDEIITSP--NLSRQSSALSTKSSN 686
            ::.::.|::.|.|.::.:.:....:...:  .|:.|.:.|.    |||  :...|.:.|..:...
 Worm   677 VLFVEGGNIVADGNHDILYEKNDAYKTFVDACETYQATSGA----TSPCGDGPAQPAPLDAEILR 737

  Fly   687 GSSSSLESMVEKEKPKPSAVSSQESRSGGQIGLSMYKKYFGAGCGVLVFVVLIMLCIGTQILASG 751
            .||..|:...:|      .:|.:|......|...:||:|..|..|..::..|::..|...:....
 Worm   738 NSSEDLKGDADK------LISDEEDMGNSTIAWRIYKQYIHAAGGWPIWTCLVIGFIVNVVSNIF 796

  Fly   752 GDYFLSYWVK--------------------NTASSSTLDIY---YFTAINVGLVICALLRTLLFF 793
            ..|:||.|:|                    :.|.|.....|   |..|: |.|.|..|.:..:|.
 Worm   797 STYWLSRWLKKGHDETTTITNGTEFLEMKTSLADSPVTGFYAAVYLVAL-VVLTISGLFKACVFV 860

  Fly   794 NITMHSSTELHNTMFQGLSRTALYFFHTNPSGRILNRFANDLGQVDEVMPAVMLDCIQIFLTLTG 858
            .:::.::|.||:.|||.:...|..||.:.|:|||||||:.|:.::|..:|......:|..:|..|
 Worm   861 KVSLTAATRLHDRMFQAVIHGATSFFDSTPTGRILNRFSKDMDEIDVKLPFTAEVFLQNMITCLG 925

  Fly   859 IICVLCVTNPWYLINTFAMMLAFYYWRDFYLKTSRDVKRLEAVARSPMYSHFSATLVGLPTIRAM 923
            .:.|:....|::|:....:.:.|..:...:....|::||.|.::|||:|.|.||:|.|:.||...
 Worm   926 FLVVITSVFPYFLLFAIPLFVVFVVFVSCFRAGIRNLKRSEHISRSPLYDHVSASLEGITTIHTF 990

  Fly   924 GAQQTLIGQYDNYQDLHSSGYYTFVSTSRAFGYYLDLFCVAY-----VISVILHNFFNPPLHNAG 983
            ......:.....:.|.:|...:.|.|..|....:|||..|..     :::|:|....:|     .
 Worm   991 QQSNRFLEVLKKHLDCNSGAIFMFQSAMRWLAVWLDLLVVVMTAIVALLTVMLTGTVSP-----A 1050

  Fly   984 QIGLAITQALGMTGMVQWGMRQSAELENAMTSVERVLEYKDLDPE-GDFNSPAEKQPPKSWPKEG 1047
            ..|:||..|:.|:|:.|:.:|...|||..|||||||..|.|..|| |::|:........|||..|
 Worm  1051 DAGMAIAFAVQMSGIFQFAVRTQTELEAKMTSVERVSYYADNIPEDGEWNTRQGLDIESSWPANG 1115

  Fly  1048 KLVTKDLSLRYEPDTNSPCVLKGLSFTIQPMEKVGIVGRTGAGKSSLINALFRL-SYNDGAILID 1111
            ::...:::|||.  .:.|..|..::|.|:..|||||:||||:|||||.|.:||| ...:|.|.||
 Worm  1116 QINFSEVNLRYR--KSHPLALNDITFEIKGGEKVGIIGRTGSGKSSLANLIFRLYPVTNGTIYID 1178

  Fly  1112 SLDTNDIGLHDLRSKISIIPQEPVLFSGTMRYNLDPFEQYPDDKLWKALEDVHLKEEISELPSGL 1176
            .:|...:||..||..||.|.|:|.|||||:|:||||..:|.|..:|:|||..|||..:..|...|
 Worm  1179 GVDIRTVGLVKLRRGISAIAQDPSLFSGTVRFNLDPSLEYSDSMIWEALEKCHLKTLVQSLDKKL 1243

  Fly  1177 QSIISEGGTNFSVGQRQLVCLARAILRENRILVMDEATANVDPQTDALIQATIRNKFKDCTVLTI 1241
            ::.:|.||.|||||:|||.|||||:|.::||:::|||||:||..||.|||..|:..|.|.||:.|
 Worm  1244 EADVSHGGNNFSVGERQLFCLARALLMKSRIVILDEATASVDAGTDKLIQEVIKTVFADATVIII 1308

  Fly  1242 AHRLNTIMDSDKVLVMDAGHVVEFGSPYEL 1271
            ||||:.:.:.|:::.:..|.::.|.:|.|:
 Worm  1309 AHRLDNVRNMDRIMHLKNGKLINFTTPQEM 1338

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31793	NP_609930.4	PLN03130	10..1305	CDD:215595	406/1330 (31%)
mrp-5	NP_510479.1	MRP_assoc_pro	90..1340	CDD:188098	401/1311 (31%)