Protein Alignment CG31793 and abcc2

DIOPT Version :9

• Sequence 1: NP_609930.4
• Gene: CG31793 / 326161
• FlyBaseID: FBgn0051793
• Length: 1307
• Species: Drosophila melanogaster
• Sequence 2: XP_004915926.1
• Gene: abcc2 / 100485020
• XenbaseID: XB-GENE-1012796
• Length: 1552
• Species: Xenopus tropicalis
• Alignment Length: 1387
• Identity: 485/1387 - (34%)
• Similarity: 740/1387 - (53%)
• Gaps: 152/1387 - (10%)

  Fly     9 NPRESAGILSSLMFCFALPILFKGRKQTLQPTDLYKTLNEHEAASLGDEFFQGWEDEVARC---- 69
            ||..:|..||.:.|.:...|:.||.|:.|:..||::...|.:..::.:.|.:..:.:|.:.
 Frog   202 NPELTASFLSRITFNWYNSIVVKGYKKPLEMEDLWELNEEDKTKNMYEIFEKHMKHDVRKAKKDL 266

  Fly    70 -RRKGDSGRKPSVLRVIG------------------------RVFG--------WRLIMSGITIA 101
             :||....:|.|.:.:.|                        .:.|        | ||.:.|...
 Frog   267 EKRKNKRKQKESGIEMNGISKAQSQDILVMEEKKKEKKKKEKSIDGTAKDYPKRW-LIKTLIKTF 330

  Fly   102 ALELGTRATVPLL--LAGLIS--------EFSEHGNGHSYNAQIYAVLLIACILASVLLTHPYMM 156
            ...|.|.|...||  |...:|        .|:...:.|.:....|||||:...|....|...|..
 Frog   331 PSTLLTSAIFKLLHDLLAFVSPQILKVMVTFTADPSQHQWQGFFYAVLLLVTALLQSFLLQQYFH 395

  Fly   157 GMMHLAMKMRVAVSSAIYRKALRLSRTSLGGTTTGQVVNLLSNDLNRFDRCLIHFHFLWLGPLEL 221
            |...|.|::|..:.:|:|:|||.:|......:|.|:.|||:|.|..||.......|.||..||::
 Frog   396 GCFVLGMRVRSLLMAAVYKKALTVSNAIRKESTVGETVNLMSADAQRFMDLTNFIHLLWSSPLQI 460

  Fly   222 LIASYFLYEQIGMASFYGISILVLYLPLQTYLSRVTSKLRLQTALRTDQRVRMMNEIISGIQVIK 286
            .|:..||:|::|.:...|:.:::|.:|:...|:.|:.||:::.....|:|:::||||::||:::|
 Frog   461 AISIVFLWEELGPSVLAGLGVMILLIPINAVLATVSRKLQMKNMKNKDKRMKIMNEILNGIKILK 525

  Fly   287 MYTWERPFGKLIGQMRRSEMSSIRQMNLLRGILL------SFEITLGRIAIFVSLLGFVLGGGEL 345
            :|.||..|...:.::|..|:..:.....|..:.|      .|.:::...|::|:    |.....|
 Frog   526 LYAWEPSFENQVQEIREKELKDMLHFTYLHSVSLFVFTCAPFLVSVATFAVYVA----VDPSNVL 586

  Fly   346 TAERAFCVTAFYNILRRTVSKFFPSGM-----SQFAELLVSMRRITNFMMREEANVIDMSERRDE 405
            .||:||...:.:||||      ||..|     |...:..||..|:..::..:.   :|.|
 Frog   587 NAEKAFTSISLFNILR------FPLAMLPMLISSMVQTSVSSARLEKYLGGDN---LDTS----- 637

  Fly   406 KAEEEQHLLKEVEKRSYPVGIGKEP--DTLVEIKALRARWGQEQHDLVLNNVNMSLRRGQLVAVI 468
                               .|..:|  |..|:.......| :|..:..:||||:.::.|.||||:
 Frog   638 -------------------AIRCDPNIDAAVQFSDATFSW-EEDANPAVNNVNLDIKEGNLVAVV 682

  Fly   469 GPVGSGKSSLIQAILGELPPESGSVQVSGKYSYASQEPWLFNASVRDNILFGLPMDKQRYRTVLK 533
            |.||||||||:.|:|||:....|.:.:.|..:|..|:.|:.||::::|||||..||::||:.||:
 Frog   683 GGVGSGKSSLVSAMLGEMDHVGGYINIKGSIAYVPQQAWIQNATLKNNILFGSKMDEERYQKVLE 747

  Fly   534 RCALERDLELLHG-DGTIVGERGASLSGGQRARICLARAVYRRADVYLLDDPLSAVDTHVGRHLF 597
            .|||..|||:|.| |.:.:||:|.:|||||:.|:.||||||..||:|:|||||||||.|||:|:|
 Frog   748 ACALLPDLEMLPGHDESEIGEKGINLSGGQKQRVSLARAVYNDADIYILDDPLSAVDAHVGKHIF 812

  Fly   598 DECM--RGFLGKQLVILVTHQLQFLEDADLIVIMDKGHVSACGTYEEMLKSGQDFAQLL------ 654
            ::.:  .|.|..:..|||||.:.||:.||.||::....|:..|:|:.:..:...||:.|
 Frog   813 EKVVGPNGLLKNKTRILVTHGVSFLKHADDIVVLVNSRVTETGSYKTLQANNGAFAEFLRLYAKQ 877

  Fly   655 -----VESTQNSG-----GGDEI--------ITSPNLSRQSSALSTKSSNGS-SSSLESMVEKEK 700
                 .|:|..:|     .||::        |.:..:.|::|....|.|:.| :.:|...|:...
 Frog   878 NDQTDNEATVFTGEDDEDDGDQVETAEVIEDIVASTVKRENSMRQRKRSSVSMNGTLRRSVKDVT 942

  Fly   701 PKPSAVSSQESR----------SGGQIGLSMYKKYF---GAGCGVLVFVVLIM---LCIGTQILA 749
            .|.:.:.|.:::          ..|::...:|.||.   |.|....:||..|:   ..:|..|..
 Frog   943 KKKTGIGSNDTKGQKLIEKETVETGKVKFKLYLKYLRAVGWGFSFWIFVSYILQNAAFVGQNIWL 1007

  Fly   750 SG--GDYFLSYWVKNTASSSTLDIYYFTAINVGLVICALLRTLLFFNITMHSSTELHNTMFQGLS 812
            |.  ||....|.:...||...:.:..|.|:.|...:..||...|.....:.:|..||..:...:.
 Frog  1008 SDWTGDAEKYYNITYPASQRDMRVGVFGALGVAQALFVLLGAFLVSGGAVRASRMLHTQLLHNIL 1072

  Fly   813 RTALYFFHTNPSGRILNRFANDLGQVDEVMPAVMLDCIQIFLTLTGIICVLCVTNPWYLINTFAM 877
            |..:.||.|.|:|||:||||.|:..|||.:|......|..||.:.|.:.::|:..|.:......:
 Frog  1073 RVPMRFFDTTPTGRIVNRFAKDILTVDETIPMSFRSWIACFLGVIGTLFIICLATPIFAAVIVPL 1137

  Fly   878 MLAFYYWRDFYLKTSRDVKRLEAVARSPMYSHFSATLVGLPTIRAMGAQQTLIGQYDNYQDLHSS 942
            .:.:|:.:.||:.|||.::||::|.|||:||||..|:.||..|||.|.|...:...::..|.:..
 Frog  1138 AIFYYFVQRFYVTTSRQLRRLDSVTRSPIYSHFGETVSGLSVIRAYGHQDRFLQHNEDTIDNNQK 1202

  Fly   943 GYYTFVSTSRAFGYYLDLFCVAYVISVILHNFFNPPLHNAGQIGLAITQALGMTGMVQWGMRQSA 1007
            ..|:::.::|.....|:......|....|.........::|.:||:|:.||.:|..:.|.:|.::
 Frog  1203 SVYSWIVSNRWLAIRLEFVGNLTVFFAALFAVLGRGTVDSGTVGLSISSALNITQTLNWLVRMTS 1267

  Fly  1008 ELENAMTSVERVLEYKDLDPEGDFNSPAEKQPPKSWPKEGKLVTKDLSLRYEPDTNSPCVLKGLS 1072
            |||..:.:||||.||..::.|..:  ..:.:|||.||::|.:...|..:||.|:.:  .||:|:|
 Frog  1268 ELETNIVAVERVDEYIKVEREAQW--VEDHRPPKDWPEKGVVQFVDYKVRYRPELD--LVLQGIS 1328

  Fly  1073 FTIQPMEKVGIVGRTGAGKSSLINALFRLSYN-DGAILIDSLDTNDIGLHDLRSKISIIPQEPVL 1136
            .||..|||||||||||||||||.|.:||:..: .|.|:||.||...|||||||.|::||||:|||
 Frog  1329 CTINSMEKVGIVGRTGAGKSSLTNCIFRIIESAGGKIMIDGLDIASIGLHDLRQKLTIIPQDPVL 1393

  Fly  1137 FSGTMRYNLDPFEQYPDDKLWKALEDVHLKEEISELPSGLQSIISEGGTNFSVGQRQLVCLARAI 1201
            |||.:|.|||||.||.|:.:|||||..|||..:..|...|...:||||.|.|||||||||||||:
 Frog  1394 FSGNLRMNLDPFNQYTDEDIWKALELSHLKPFVEGLQEKLFHEVSEGGENLSVGQRQLVCLARAL 1458

  Fly  1202 LRENRILVMDEATANVDPQTDALIQATIRNKFKDCTVLTIAHRLNTIMDSDKVLVMDAGHVVEFG 1266
            ||:::||::|||||.||.:||.|||.|||::|.|||||||||||:|||||.:::|:|||.::|||
 Frog  1459 LRKSKILILDEATAAVDLETDNLIQRTIRSEFADCTVLTIAHRLHTIMDSSRLMVLDAGKIIEFG 1523

  Fly  1267 SPYELLTASKAKVFHGMVMQTG 1288
            ||.|||  .:...|..|....|
 Frog  1524 SPDELL--QRQGHFFSMAKDAG 1543

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31793	NP_609930.4	CFTR_protein	1..1273	CDD:273530	481/1370 (35%)
		ABC_membrane	112..364	CDD:294371	80/267 (30%)
		ABCC_MRP_domain1	434..632	CDD:213217	97/200 (49%)
		ABC_membrane	736..955	CDD:294371	69/223 (31%)
		ABCC_MRP_domain2	1047..1268	CDD:213211	135/221 (61%)
abcc2	XP_004915926.1	MRP_assoc_pro	10..1544	CDD:188098	485/1387 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG51855
OrthoDB	1	1.010	-	-		D138195at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.020