Protein Alignment CG31793 and abcc10

DIOPT Version :9

• Sequence 1: NP_609930.4
• Gene: CG31793 / 326161
• FlyBaseID: FBgn0051793
• Length: 1307
• Species: Drosophila melanogaster
• Sequence 2: NP_001135594.1
• Gene: abcc10 / 100216149
• XenbaseID: XB-GENE-6465377
• Length: 1501
• Species: Xenopus tropicalis
• Alignment Length: 1345
• Identity: 450/1345 - (33%)
• Similarity: 707/1345 - (52%)
• Gaps: 181/1345 - (13%)

  Fly    17 LSSLMFCFALPILFKGRKQTLQ-PTDLYKTLNEHEAASLGDEFFQGWEDEVARCRRKGDSGRKPS 80
            ||...:.:..|:|.:|.:..|: |.|:  .|..|   .||          .||..:...|....:
 Frog   231 LSRFFYLWLNPLLRQGARGGLKHPGDV--LLLPH---CLG----------TARICQHFQSKSSST 280

  Fly    81 VLRVIGRV---FGWRLIMSGITIAALELG--TRATVPLLLAGLISEFSEHGN-----GHSYNAQI 135
            :||::..:   ||.|....|:    |:||  |.|.:..||..|:..|.|..:     |..|...:
 Frog   281 ILRLLPTLHASFGARYYALGL----LKLGAVTLAFLGPLLLNLLVNFMEAADEPLSWGILYTLGL 341

  Fly   136 YAVLLIACILASVLLTHPYMMGMMHLAMKMRVAVSSAIYRKALRLSRTSLGGTTTGQVVNLLSND 200
            ::    :|.||: ||.:.:...:..|.:.:|.:|.:::||||:|...|.|.|.:.|::||.:|.|
 Frog   342 FS----SCFLAA-LLQNQFTHEVNKLILAVRASVLTSVYRKAIRGVGTGLAGFSKGEIVNFMSTD 401

  Fly   201 LNRFDRCLIHFHFLWLGPLELLIASYFLYEQIGMASFYGISILVLYLPLQTYLSRVTSKLRLQTA 265
            .:|.......||.:|..||:..:..|.||.|:|:|...|:.:.||.||:...::...........
 Frog   402 ADRISNFCRSFHEVWSLPLQFSVTLYLLYLQVGIAFLGGLGLAVLLLPINKVIANRIVDYNSDLL 466

  Fly   266 LRTDQRVRMMNEIISGIQVIKMYTWERPFGKLIGQMRRSEMSSIRQMNLLRGILLSFEITLGRIA 330
            ...|.||::|.|::||::|:|.||||:.|.:.:..:|..|:.|:|.:.:|..:.:.....|..:.
 Frog   467 NHKDARVKLMTELLSGMRVVKFYTWEKHFAEAVTSLREKELRSLRALKMLDAVCVYLWAALPVLI 531

  Fly   331 IFVSLLGFVLGGGELTAERAFCVTAFYNILRRTVSKFFPSGMSQFAELLVSMRRITNFMMREEAN 395
            ..::.:.:||.|.:|||.:.|...|...:|...::. ||..::...|..||:.||..||
 Frog   532 SIITFITYVLLGHQLTAAKVFTALALVGMLILPLNN-FPWVLNGVLEAKVSLERIQLFM------ 589

  Fly   396 VIDMSERRDEKAEEEQHLLKEVEKRSYPVGIGKEPDTLVEIKALRARWGQEQHD----LVLNNVN 456
              |:         .||.||....:.. |.    :|.:.:|:::....|..|:.:    |.|...:
 Frog   590 --DL---------PEQDLLNYYSQEP-PA----DPSSALELRSAAFSWMPEESEDSGSLQLFIEH 638

  Fly   457 MSLRRGQLVAVIGPVGSGKSSLIQAILGELPPESGSVQVSGK---YSYASQEPWLFNASVRDNIL 518
            :|:::|.||.|:|.||.|||||:.|:.|||....|.:..|.:   :.:|:||||:..|::|:|||
 Frog   639 LSVQKGVLVGVVGKVGCGKSSLLAALTGELSRSGGELFASHQELGFGFAAQEPWIQFATIRENIL 703

  Fly   519 FGLPMDKQRYRTVLKRCALERDLELL-HGDGTIVGERGASLSGGQRARICLARAVYRRADVYLLD 582
            ||...:.:.|:.||:.|||..||.:| .||.|.|||.|.:|||||:||:.||||||:..|:||||
 Frog   704 FGKEFNGKLYQGVLEACALNDDLSILPSGDQTEVGENGVTLSGGQKARLALARAVYQDKDIYLLD 768

  Fly   583 DPLSAVDTHVGRHLFDECMRGFLGKQLVILVTHQLQFLEDADLIVIMDKGHVSACGTYEEMLKSG 647
            |||:|||..|..||.::|:.|.|..:..||.||:.:.|:.||::::|:.|.:...||.:::|.
 Frog   769 DPLAAVDADVAAHLMEKCILGILKNKTRILCTHRTELLDKADIVLLMEGGKMVGSGTPDKILP-- 831

  Fly   648 QDFAQLLVESTQNSGGGDEIITSPNLSRQSSALSTKSSNGSSSSLESMVEKEKP--------KP- 703
                  ||||::|.|               |...|:.::.|.::.:|:.|.|:.        :|
 Frog   832 ------LVESSRNRG---------------SRGQTQMNHISQAAEQSLEEDEEEAENEGNPIQPI 875

  Fly   704 SAVSSQESRSGGQIGLSMYKKYFGAGCGVLVFVVLIMLCIGTQILASGGDYFLSYWVKN------ 762
            :|...||.:..|.:.|.:|..|:.|..|.|...||:.|.: .|...:..|::||:|:.:
 Frog   876 TAEVGQEEKQEGAVALQVYWAYWKAVGGCLAGSVLLALFL-MQASRNISDWWLSHWISSLQDSPR 939

  Fly   763 -------TASS---------------------------STLDIYYFTAINVGLVIC----ALLRT 789
                   |.||                           |:|||.::.::..|:.:.    ..||.
 Frog   940 NVSLTNLTPSSFPSASLLLFSQGGLVSPISSVHSAEKNSSLDITFYLSVYGGIAVANSIFTALRA 1004

  Fly   790 LLFFNITMHSSTELHNTMFQGLSRTALYFFHTNPSGRILNRFANDLGQVDEVMPAVMLDCIQIFL 854
            .||...|:|::..:|..:...:.:..:.||.:.|.|||:|||::||..||:.:|.|    :.|||
 Frog  1005 FLFALGTVHAAVVIHRRLLSSVLQATVSFFDSTPIGRIINRFSSDLYCVDDSLPFV----LNIFL 1065

  Fly   855 TLT----GIICVLCVTNPWYLINTFAMMLAFYYWRDFYLKTSRDVKRLEAVARSPMYSHFSATLV 915
            ..|    |::.::....||.|.....:.|.:||.:.||..:||::|||:::..||:|:|||.||.
 Frog  1066 AFTFGLLGMLVMISYGLPWILPVLLPLCLLYYYLQRFYRHSSRELKRLQSITLSPIYTHFSETLT 1130

  Fly   916 GLPTIRAMGAQQTLIGQYDNYQDLHSSGYYTFVSTSRAFGYYLDL---------FCVAYVISVIL 971
            ||.||||.........:..:..:::....:    .|.|...:||:         .....||::|.
 Frog  1131 GLTTIRATRHADRFEAECVSRLEVNQRCMF----ASNAAVQWLDIRLQMIGVMVVAAISVIAIIQ 1191

  Fly   972 HNFFNPPLHNAGQIGLAITQALGMTGMVQWGMRQSAELENAMTSVERVLEYKDLDP----EGDFN 1032
            |   .....:.|.:|||::.||.:||::...:....:.|..|.||||..||....|    ||..
 Frog  1192 H---QRKSGDPGLVGLALSYALSITGILSGLISSFTQTEAMMVSVERTEEYSTTLPSESAEGSL- 1252

  Fly  1033 SPAEKQPPKSWPKEGKLVTKDLSLRYEPDTNSPCVLKGLSFTIQPMEKVGIVGRTGAGKSSLINA 1097
                 |....||..|.:..:::.|.|.  ...|..|.|:||||.|.||:|||||||:|||:|..|
 Frog  1253 -----QVELDWPTNGHIEFRNVVLCYR--LGLPNALDGISFTISPGEKIGIVGRTGSGKSTLFLA 1310

  Fly  1098 LFR-LSYNDGAILIDSLDTNDIGLHDLRSKISIIPQEPVLFSGTMRYNLDPFEQYPDDKLWKALE 1161
            ||| :...:|:||||::.::.:.|..|||:::||||:..||||::|.||||...:.|.::.|.|:
 Frog  1311 LFRMMELKEGSILIDNVPSHLLNLELLRSRLAIIPQDAFLFSGSVRVNLDPLSYHTDVEILKVLD 1375

  Fly  1162 DVHLKEEISELPSGLQSIISEGGTNFSVGQRQLVCLARAILRENRILVMDEATANVDPQTDALIQ 1226
            ..||::.:..: .||.:.:.:.|.|||:|||||:|||||:|...:||.:|||||:||.|||.|:|
 Frog  1376 QCHLQDVVRRI-GGLDADVGDRGKNFSLGQRQLLCLARALLTHAKILCIDEATASVDHQTDELLQ 1439

  Fly  1227 ATIRNKFKDCTVLTIAHRLNTIMDSDKVLVMDAGHVVEFGSPYEL 1271
            .|||.:|::.||||||||||||||||:||||.||.:||..||..|
 Frog  1440 RTIRERFRERTVLTIAHRLNTIMDSDRVLVMHAGKLVELDSPANL 1484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31793	NP_609930.4	CFTR_protein	1..1273	CDD:273530	450/1345 (33%)
		ABC_membrane	112..364	CDD:294371	74/256 (29%)
		ABCC_MRP_domain1	434..632	CDD:213217	90/205 (44%)
		ABC_membrane	736..955	CDD:294371	72/266 (27%)
		ABCC_MRP_domain2	1047..1268	CDD:213211	114/221 (52%)
abcc10	NP_001135594.1	MRP_assoc_pro	180..1484	CDD:188098	449/1343 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D138195at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010