Protein Alignment ninaD and SCARB2

DIOPT Version :9

• Sequence 1: NP_724087.1
• Gene: ninaD / 326160
• FlyBaseID: FBgn0002939
• Length: 513
• Species: Drosophila melanogaster
• Sequence 2: NP_005497.1
• Gene: SCARB2 / 950
• HGNCID: 1665
• Length: 478
• Species: Homo sapiens
• Alignment Length: 497
• Identity: 141/497 - (28%)
• Similarity: 230/497 - (46%)
• Gaps: 46/497 - (9%)

  Fly     5 CCGVTQQKAWVFGLGTFFAVSGLLAIICWPGFIDSGIMKALPLTPTSKTFEKWEELPIPVYVYMY 69
            ||..|   |....|........||....:...:|..|.|.:.|...::.|:.||:.|:|||...|
Human     4 CCFYT---AGTLSLLLLVTSVTLLVARVFQKAVDQSIEKKIVLRNGTEAFDSWEKPPLPVYTQFY 65

  Fly    70 LWNWTNAADVQANGVKPIFAQLGPYVYREERKKMDLEWHDNG-TVTFNPRRTWFWEEELS-GGKQ 132
            .:|.||..:: ..|..|...::|||.|||.|.|.::::.||| |::....:.:.:|.:.| |..:
Human    66 FFNVTNPEEI-LRGETPRVEEVGPYTYRELRNKANIQFGDNGTTISAVSNKAYVFERDQSVGDPK 129

  Fly   133 TDLITAPHLPSLAASNQMRNSNV-FLKFMFNEALNANGGHLFVTHTAAEWLFESFYDEFLHYAMT 196
            .|||...::|.|..   :..|.| ||:.:....|.|....||||||..|.|: .:.||.|    :
Human   130 IDLIRTLNIPVLTV---IEWSQVHFLREIIEAMLKAYQQKLFVTHTVDELLW-GYKDEIL----S 186

  Fly   197 LNNPLVPKIESDHFAWFLNRNGSKDFEGPFTVHTGVGDIKEMGEIKYWKGQNHTGWY-DGECGRL 260
            |.:...|.| |.:|..|..:||:.|  |.:...||........:|..|.|:....|: ..:|..:
Human   187 LIHVFRPDI-SPYFGLFYEKNGTND--GDYVFLTGEDSYLNFTKIVEWNGKTSLDWWITDKCNMI 248

  Fly   261 NGSTTDLFVPDEPKEKALTIFIPDTCRIINLEFTGQSETIQGITGWKY----EITPNTFDNGQIN 321
            ||:..|.|.|...|::.|.:|..|.||.:.:.|: ..|::||:..::|    ||..||.||..
Human   249 NGTDGDSFHPLITKDEVLYVFPSDFCRSVYITFS-DYESVQGLPAFRYKVPAEILANTSDNAG-- 310

  Fly   322 GNAKCWCPLERQPDNCPATGATDLGPCADGVPMYLSADHFMYADESYGSTISGYNPNYDQNNFYI 386
                 :|..|   .||..:|..::..|.:|.|:.:|..||..|||.:.|.|.|.:||.:.:..::
Human   311 -----FCIPE---GNCLGSGVLNVSICKNGAPIIMSFPHFYQADERFVSAIEGMHPNQEDHETFV 367

  Fly   387 IMERKMGVPLKVNANVMITLYIEP-DSVIDILKGLPSFYAPLFTTASRAEIDEALASELRLALNL 450
            .:....|:.||......|.:|::. |..:: ...:.:...|:........||:..||.|:..:|.
Human   368 DINPLTGIILKAAKRFQINIYVKKLDDFVE-TGDIRTMVFPVMYLNESVHIDKETASRLKSMINT 431

  Fly   451 PAIGRYTGVGFLCLGCILIAVGILLTIKRKWY---GQAELDK 489
            ..|  .|.:.:     |::|:|:...:...|.   ||..:|:
Human   432 TLI--ITNIPY-----IIMALGVFFGLVFTWLACKGQGSMDE 466

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ninaD	NP_724087.1	CD36	19..474	CDD:279474	132/463 (29%)
SCARB2	NP_005497.1	CD36	28..455	CDD:307331	130/457 (28%)
		Important for interaction with GBA	155..191		14/40 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3776
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1106566at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11923
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X155
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.920