DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ninaD and Snmp2

DIOPT Version :9

Sequence 1:	NP_724087.1	Gene:	ninaD / 326160	FlyBaseID:	FBgn0002939	Length:	513	Species:	Drosophila melanogaster
Sequence 2:	NP_001163372.1	Gene:	Snmp2 / 38868	FlyBaseID:	FBgn0035815	Length:	556	Species:	Drosophila melanogaster

Alignment Length:	548	Identity:	130/548 - (23%)
Similarity:	224/548 - (40%)	Gaps:	101/548 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 VFGLGTFFAV-SGLLAIICWPGFIDSGIMKALPLTPTSKTFEKWEELPIPVYVYMYLWNWTNAAD 78
            |..||...|| .|....|.:|..:...:.:::.:...|:.|:::..||.|:...:|::|.||:..
  Fly     8 VSALGVCVAVLGGYCGWILFPNMVHKKVEQSVVIQDGSEQFKRFVNLPQPLNFKVYIFNVTNSDR 72

  Fly    79 VQANGVKPIFAQLGPYVYREERKK-------------------MDLE-------WHDNGTVTFNP 117
            :| .|..||..::|||||::.|:|                   .|.:       ..|:..|..|.
  Fly    73 IQ-QGAIPIVEEIGPYVYKQFRQKKVKHFSRDGSKISYVQNVHFDFDAVASAPYTQDDRIVALNM 136

  Fly   118 RRTWFWE----------------------------------EELSGGKQTDLITAPHLPSLAASN 148
            ....|.:                                  |.:.|.:::.|..:.:.|.||...
  Fly   137 HMNAFLQVFEREITDIFQGFANRLNSRLNQTPGVRVLKRLMERIRGKRKSVLQISENDPGLALLL 201

  Fly   149 QMRNSNVFLKFMFNEALNANGGHLFVTHTAAEWLFES--FYDEFLHYAMTLNNPL------VPKI 205
            ...|:|  ||.:||:..:     :||:.:..|:||:.  |.......|..:.|.:      ..:.
  Fly   202 VHLNAN--LKAVFNDPRS-----MFVSTSVREYLFDGVRFCINPQGIAKAICNQIKESGSKTIRE 259

  Fly   206 ESD---HFAWFLNRNGSKDFEGPFTVHTGVGDIKEMGEI-KYWKGQNHTGWY----DGE---CGR 259
            :||   .|::|.::|||.  ...:.||||.||...:.|| |.....|...|.    :||   |.:
  Fly   260 KSDGSLAFSFFGHKNGSG--HEVYEVHTGKGDPMRVLEIQKLDDSHNLQVWLNASSEGETSVCNQ 322

  Fly   260 LNGSTTDLFVPDEPKEKALTIFIPDTCRIINLEFTGQSETIQGITGWKYEITPNTF-DNGQINGN 323
            :||:....:.|...:..::.||..|.||.:.| |.......|||.|::|.|..|.. |.|..:.|
  Fly   323 INGTDASAYPPFRQRGDSMYIFSADICRSVQL-FYQTDIQYQGIPGYRYSIGENFINDIGPEHDN 386

  Fly   324 AKCWC-----PLERQPDNCPATGATDLGPCADGVPMYLSADHFMYADESYGSTISGYNPNYDQNN 383
             :|:|     .:.::.:.|...||.||..|.| .|:.|:..|.:.|...|...|.|..|:..::.
  Fly   387 -ECFCVDKLANVIKRKNGCLYAGALDLTTCLD-APVILTLPHMLGASNEYRKMIRGLKPDAKKHQ 449

  Fly   384 FYIIMERKMGVPLKVNANVMITLYIEPDSVIDILKGLPSFYAPLFTTASRAEID-EALASELRLA 447
            .::.::...|.||:....|...::::..:.|.|.:.||:...|........::: |.:|...:..
  Fly   450 TFVDVQSLTGTPLQGGKRVQFNMFLKSINRIGITENLPTVLMPAIWVEEGIQLNGEMVAFFKKKL 514

  Fly   448 LNLPAIGRYTGVGFLCLGCILIAVGILL 475
            :|............|| |.|.:||..|:
  Fly   515 INTLKTLNIVHWATLC-GGIGVAVACLI 541

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ninaD	NP_724087.1	CD36	19..474	CDD:279474	127/541 (23%)
Snmp2	NP_001163372.1	CD36	10..543	CDD:395898	129/546 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45450742
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3776
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1106566at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11923
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X155
	6	5.850