DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ninaD and dsb

DIOPT Version :9

Sequence 1:	NP_724087.1	Gene:	ninaD / 326160	FlyBaseID:	FBgn0002939	Length:	513	Species:	Drosophila melanogaster
Sequence 2:	NP_001097477.1	Gene:	dsb / 38252	FlyBaseID:	FBgn0035290	Length:	615	Species:	Drosophila melanogaster

Alignment Length:	477	Identity:	119/477 - (24%)
Similarity:	217/477 - (45%)	Gaps:	41/477 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 VTQQKAWVFGLGTFFAVSG-LLAIICWPGFIDSGIMKALPLTPTSKTFEKWEELPIPVYVYMYLW 71
            ::..:..|..:|....:.| :|:.:.|   :|..|:|.|.|...:.::..|:...:.....:|::
  Fly    75 ISNNRLAVIIIGIITLILGIILSSMPW---LDYFILKNLRLWNDTLSYHYWQRPGVIRLTKLYIY 136

  Fly    72 NWTNAADVQANGVKPIFAQLGPYVYREERKKMDLEWHDNG-TVTFNPRRTWFWEEELSGGKQTDL 135
            |.|| .|....|.||...::||:||||:.:|:::::|:|. ||::..::...:..|||..|.|.
  Fly   137 NVTN-PDGFLRGEKPHLQEVGPFVYREDMQKVNVKFHENNYTVSYQHKKILQFVPELSIDKDTP- 199

  Fly   136 ITAPHLPSLAASNQMRNSNVFLKFMFNEALNANGGHLFVTHTAAEWLFESFYDEFLHYAMTLNNP 200
            ||.|::|.|..::........|....:..:.|.....|:..||.:..|.  ||:.|   ::|.:.
  Fly   200 ITTPNIPLLTLTSLSPKLGYLLSKTISVVVTAAQFKPFINVTAEQLAFG--YDDAL---VSLAHR 259

  Fly   201 LVPK--IESDHFAWFLNRNGSKDFEGPFTVHTGVGDIKEMGEIKYWKGQNH-TGWYDGECGRLNG 262
            ..||  ...:.....|.|||:  .....:|.||:..:.:.|.|....|.:| ..|.:..|..:.|
  Fly   260 FYPKHMRPMERMGLLLGRNGT--LTEVSSVKTGMDSMDQFGYIDQLNGLDHLPHWSEPPCTSIAG 322

  Fly   263 STTDLFVPDE-PKEKALTIFIPDTCRIINLEFTGQSETIQGITGWKYEITPNTFDNGQINGNAKC 326
            |....|.|.| .|.:.:.|:..|.||||.|::....|. .||....:.:..|::.:...|...||
  Fly   323 SEGSFFPPRELTKSEVVHIYDKDLCRIIPLKYVESLEK-DGIAADLFRLPNNSYGDSAHNPENKC 386

  Fly   327 WCPLERQPDNCPATGATDLGPCADGVPMYLSADHFMYADESYGSTISGYNPNYDQNNFYIIMERK 391
            :...|.:    |..|..::.||..|.|:|:|..||..:.....:::.|..|..:::..|..::.|
  Fly   387 YDTSEYE----PIQGLQNISPCQYGAPVYISNPHFFESHPDLLNSVEGLKPEREKHETYFKIQPK 447

  Fly   392 MGVPLKVNANVMITLYIEPDSVIDILKGLPSFYAPLFTTASRAEIDEALASELRLALNLPAIGRY 456
            :||||:....:.:.|.:.....:..::....|..|:..      ::|.: |||     .|||.|:
  Fly   448 LGVPLEGKVRIQLNLKVTRAKDVYPVRDFRDFVFPVMW------LEEGI-SEL-----TPAIKRW 500

  Fly   457 TGVGFLC------LGCILIAVG 472
            ..:|.:.      :|..|:.:|
  Fly   501 IYLGTVIAPSAVPIGSYLMILG 522

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ninaD	NP_724087.1	CD36	19..474	CDD:279474	118/466 (25%)
dsb	NP_001097477.1	CD36	103..532	CDD:279474	114/446 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45450710
Domainoid	1	1.000	248	1.000	Domainoid score	I2091
eggNOG	1	0.900	-	-		E1_KOG3776
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1106566at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11923
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X155
	7	6.850