DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ninaD and emp

DIOPT Version :9

Sequence 1:	NP_724087.1	Gene:	ninaD / 326160	FlyBaseID:	FBgn0002939	Length:	513	Species:	Drosophila melanogaster
Sequence 2:	NP_726504.2	Gene:	emp / 37999	FlyBaseID:	FBgn0010435	Length:	551	Species:	Drosophila melanogaster

Alignment Length:	536	Identity:	138/536 - (25%)
Similarity:	246/536 - (45%)	Gaps:	61/536 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 CCSCCGVTQQKAWVFGLGTFFAVSGLLAIIC-WPGFIDSGIMKALPLTPTSKTFEKWEELPIPVY 65
            |........:|.|:..:.....:.|.:.:.| :...||:.:.:.:.|.|.:|||..|.:.|:...
  Fly    40 CTKLSSTYLRKWWITIVVAAALIIGGIVVACEFTVLIDAVVDRMVALRPGAKTFGWWAKPPVEPR 104

  Fly    66 VYMYLWNWTNAADVQANGVKPIFAQLGPYVYREERKKMDLEWHDNGTVTFNPRRTWFWEEELSGG 130
            :.:|::|.|||.|..:||.|.|..::|||||.|..:|:::..:||||:::|.|:.:.:.|:||.|
  Fly   105 ISLYIYNVTNADDFLSNGSKAIVDEVGPYVYSETWEKVNIVENDNGTLSYNLRKIYSFREDLSVG 169

  Fly   131 KQTDLITAPHLPSLAASNQMRNSNVFLKFMFNEALNANGGHLFVTHTAAEWLFESFYDEFLHYAM 195
            .:.|::..|::|.|:|::|.:::..||:......::......||..:..:.|:.  |::.|   :
  Fly   170 PEDDVVIVPNIPMLSATSQSKHAARFLRLAMASIMDILKIKPFVQVSVGQLLWG--YEDPL---L 229

  Fly   196 TLNNPLVP---KIESDHFAWFLNRNGSKDFEGPFTVHTGVGDIKEMGEIKYWKGQNH-TGWYDGE 256
            .|...:||   |:..:.|.....:||:.  ....||:|||.||:..|.|..:.|:.| ..|....
  Fly   230 KLAKDVVPKEQKLPYEEFGLLYGKNGTS--SDRVTVNTGVDDIRRYGIIDNFNGRTHLPHWTTDA 292

  Fly   257 CGRLNGSTTDLFVPDEPKEKALTIFIPDTCRIINLEFTGQSETIQGITGWKYEITPNTFDNGQIN 321
            |..|.|:...:|.|....::.|.::..|.||::.|.|..:..|...:.|:::......|.:...:
  Fly   293 CNTLAGTDGSIFPPHIDHDRILHVYDKDLCRLLPLVFEKEVMTSNEVPGYRFTPPEWVFADVDSH 357

  Fly   322 GNAKCWCPLERQPDNCPATGATDLGPCADGVPMYLSADHFMYADESYGSTISGYNPNY-DQNNFY 385
            .:..|:||..:  .:|...|..::..|....|:.||..||..||||..:.:.|.:|.. :::.|:
  Fly   358 PDNMCFCPAGK--PSCSPNGLFNVSLCQYDSPIMLSFPHFYLADESLRTQVEGISPPMKEKHQFF 420

  Fly   386 IIMERKMGVPLKVNANVMITLYIE-----------PDSVIDIL------KGLPSFYAPLFTTASR 433
            ..::.|||..|:|.|.:.|.|.:.           ||.:..||      ..||.....|...|
  Fly   421 FDVQPKMGTTLRVRARIQINLAVSQVFDIKQVANFPDIIFPILWFEEGIDNLPDEVTDLMRFA-- 483

  Fly   434 AEIDEALASELRLALNLPAIGRYTGVGFLCLGCILIAVGILLTIKRKW--------------YGQ 484
                |.:..::|:||.         ||...||.||:.:.....|:...              ..|
  Fly   484 ----EQVPPKIRVALI---------VGLCALGVILLLLSTFCLIRNSHRQSTLHLEGSNYLATAQ 535

  Fly   485 AELDKLALKDNEETPY 500
            .:::|...|||:...|
  Fly   536 VDMNKKQNKDNQPARY 551

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ninaD	NP_724087.1	CD36	19..474	CDD:279474	128/477 (27%)
emp	NP_726504.2	CD36	58..511	CDD:279474	128/476 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45450716
Domainoid	1	1.000	248	1.000	Domainoid score	I2091
eggNOG	1	0.900	-	-		E1_KOG3776
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1106566at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11923
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X155
	7	6.850