DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rngo and NRIP2

DIOPT Version :9

Sequence 1:	NP_001285328.1	Gene:	rngo / 32616	FlyBaseID:	FBgn0030753	Length:	458	Species:	Drosophila melanogaster
Sequence 2:	XP_016875489.1	Gene:	NRIP2 / 83714	HGNCID:	23078	Length:	294	Species:	Homo sapiens

Alignment Length:	172	Identity:	38/172 - (22%)
Similarity:	75/172 - (43%)	Gaps:	38/172 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   181 REHITERKRRNEHRMRMLNADPFD----EETQRL-IAEEIKQKN-IQDNMAAAIEYNPE------ 233
            |.|::: :||.:...:.|:.|..|    :..:|| .:::::.:: ||..:   :|.||.
Human    76 RAHLSQ-QRRLKQATQFLHKDSADLLPLDSLKRLGTSKDLQPRSVIQRRL---VEGNPNWLQGEP 136

  Fly   234 ------IFG----------TVTMLYINCKVNGIPVKAFVDSGAQTTIMSKDCAERCHV-NRLIDT 281
                  |.|          .:..|.:|||.....::..||:|.|...:|..|..|..: .|::..
Human   137 PRMQDLIHGQESRRKTSRTEIPALLVNCKCQDQLLRVAVDTGTQYNRISAGCLSRLGLEKRVLKA 201

  Fly   282 RWNGVAKGVGTQPILGRIHMVQLQIENDHLTSSFTVLGQQPM 323
            ....:|.|..||     :..::||:..:.:..|..|:|:.|:
Human   202 SAGDLAPGPPTQ-----VEQLELQLGQETVVCSAQVVGKSPL 238

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rngo	NP_001285328.1	UBQ	1..73	CDD:214563
		DDI1_N	3..72	CDD:176391
		RP_DDI	225..344	CDD:133146	27/122 (22%)
		UBA	411..445	CDD:279021
NRIP2	XP_016875489.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0012
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR12917
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.910