DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment rngo and DDI1

DIOPT Version :9

Sequence 1:	NP_001285328.1	Gene:	rngo / 32616	FlyBaseID:	FBgn0030753	Length:	458	Species:	Drosophila melanogaster
Sequence 2:	NP_001189877.1	Gene:	DDI1 / 820522	AraportID:	AT3G13235	Length:	414	Species:	Arabidopsis thaliana

Alignment Length:	464	Identity:	161/464 - (34%)
Similarity:	236/464 - (50%)	Gaps:	72/464 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKITVTTSDDKVFCLDVAQDLELENLKALCAMEIGAEVSQIAVIFNGREL-SSDKQTLQQCGVGD 64
            |:|||.|:.:::..|||.....:||:|||..:|....:.|..:::||.|: :|||  |...||.|
plant     1 MRITVMTAGEQIITLDVDSQETVENVKALLEVESNVPIQQQQLLYNGNEMGNSDK--LSALGVKD 63

  Fly    65 GDFIMLERRRSANRPVGGNPAISTLDFSNIAVPGTSSGGSPPSRRVQQQGVQQPQFNNLTDIPTT 129
            .|.:|:   ..:|...|          |..:..|...|.:|....:.....||
plant    64 DDLLMM---MVSNASSG----------SATSAAGNDLGMNPDGSALNPAAFQQ------------ 103

  Fly   130 DEFNVNFDDDPETVRQMFLSSPETLSLLRQYNPSLAEAIDSGDKEKFARLLREHITER---KRRN 191
                 :...|...:.|:|           |.:|.||:.|...|..|...:||....:|   :|:.
plant   104 -----HIRGDSNLMGQLF-----------QNDPELAQVISGSDLNKLQDVLRARHRQRSVLQRQK 152

  Fly   192 EHRMRMLNADPFDEETQRLIAEEIKQKNIQDNMAAAIEYNPEIFGTVTMLYINCKVNGIPVKAFV 256
            |..:.:|.|||||.|.||.|...|:||.|.:|..||:|:|||.|..|.|||::.:|||:|:||||
plant   153 EEELALLYADPFDVEAQRKIEAAIRQKGIDENWEAALEHNPEGFARVIMLYVDMEVNGVPLKAFV 217

  Fly   257 DSGAQTTIMSKDCAERCHVNRLIDTRWNGVAKGVGTQPILGRIHMVQLQIENDHLTSSFTVLGQQ 321
            |||||:||:||.|||||.:.||:|.|:.|:|.|||...||||||:..::|.|:....||.||...
plant   218 DSGAQSTIISKSCAERCGLLRLMDQRYKGIAHGVGQTEILGRIHVAPIKIGNNFYPCSFVVLDSP 282

  Fly   322 PMDMLLGLDMLKRHQCLIDLQRNLLIIGTTGTTTPFLPESELPV----------SARLTGNSEDS 376
            .|:.|.|||||::|||.|||:.|::.:|....:.|||.|.::|.          .|..:|.:..|
plant   283 NMEFLFGLDMLRKHQCTIDLKENVMTVGGGEVSVPFLQEKDIPSRFLDEERVPNDASSSGATVPS 347

  Fly   377 MEQEAISNAI-----EQSKRESGGAGGGPNTISPQERFTEQDVTDLMALGYPRSDVLTVLRLCGG 436
            ...|..:|.:     :|.||::...|       |:   .|..:..|:.||:.|..|:..|:|..|
plant   348 GFTEKKNNTVANPTSQQPKRQNTSEG-------PE---FEAKIAKLVELGFSRDSVIQALKLFEG 402

  Fly   437 NKQAARSVL 445
            |::.|...|
plant   403 NEEQAAGFL 411

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rngo	NP_001285328.1	UBQ	1..73	CDD:214563	27/72 (38%)
		DDI1_N	3..72	CDD:176391	26/69 (38%)
		RP_DDI	225..344	CDD:133146	67/118 (57%)
		UBA	411..445	CDD:279021	11/33 (33%)
DDI1	NP_001189877.1	Ubl_Ddi1_like	1..71	CDD:340494	27/74 (36%)
		PRK12545	<132..>211	CDD:183584	34/78 (44%)
		RP_DDI	186..309	CDD:133146	68/122 (56%)
		UBA_scDdi1_like	377..412	CDD:270494	12/35 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	145	1.000	Domainoid score	I1478
eggNOG	1	0.900	-	-		E1_KOG0012
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H121661
Inparanoid	1	1.050	240	1.000	Inparanoid score	I1086
OMA	1	1.010	-	-		QHG54960
OrthoDB	1	1.010	-	-		D817208at2759
OrthoFinder	1	1.000	-	-		FOG0002352
OrthoInspector	1	1.000	-	-		oto3536
orthoMCL	1	0.900	-	-		OOG6_101685
Panther	1	1.100	-	-	LDO	PTHR12917
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1784
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840