DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rngo and Nrip3

DIOPT Version :9

Sequence 1:	NP_001285328.1	Gene:	rngo / 32616	FlyBaseID:	FBgn0030753	Length:	458	Species:	Drosophila melanogaster
Sequence 2:	NP_065635.1	Gene:	Nrip3 / 78593	MGIID:	1925843	Length:	240	Species:	Mus musculus

Alignment Length:	251	Identity:	50/251 - (19%)
Similarity:	103/251 - (41%)	Gaps:	61/251 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   169 DSGDKE---KFARLLREHITERKRRNEHRMRMLNAD-----PFD--------EETQRLIAEEIKQ 217
            :.|.||   :.|..||:     :||.:..::.::.|     |.|        ::||   ...|.|
Mouse     9 EGGRKETDMREAASLRQ-----QRRMKQAVQFIHKDSADLLPLDGLKKLGSSKDTQ---PHNILQ 65

  Fly   218 KNIQDNMAAAIEYNPEIFGTVT------------------MLYINCKVNGIPVKAFVDSGAQTTI 264
            :.:.:...:.:......:.:.|                  |:.::|:..|..|||.||:|.|..:
Mouse    66 RRLMETNLSKLRSTRVPWASKTNKFNQAKSEGLKKCEDEDMILVSCQCAGKDVKALVDTGCQYNL 130

  Fly   265 MSKDCAERCHVNRLIDTRWNGVAKGVGTQ-------PILGRIHMVQLQIENDHLTSSFTVLGQQP 322
            :|..|.:|..:...:.:.     |..|.:       .::|:|..:.:.:.:..|.....|:....
Mouse   131 ISSACVDRLGLKDHVKSH-----KHEGEKLSLPRHLKVVGQIEHLMITVGSLRLDCQAAVVDDNE 190

  Fly   323 MDMLLGLDMLKRHQCLIDLQRNLLIIGTTGTTTPFLPESELPVSARLTGNSEDSME 378
            ..:.|||..|:..:|:|:|.::.||:|.|       .:.|:|....::.|.:::.|
Mouse   191 KSLSLGLQTLRSLKCIINLDKHRLIVGKT-------DKEEIPFVETVSVNDDNTSE 239

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rngo	NP_001285328.1	UBQ	1..73	CDD:214563
		DDI1_N	3..72	CDD:176391
		RP_DDI	225..344	CDD:133146	27/143 (19%)
		UBA	411..445	CDD:279021
Nrip3	NP_065635.1	NRIP_C	109..211	CDD:133147	25/106 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0012
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12917
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910