DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rngo and Ddi2

DIOPT Version :9

Sequence 1:	NP_001285328.1	Gene:	rngo / 32616	FlyBaseID:	FBgn0030753	Length:	458	Species:	Drosophila melanogaster
Sequence 2:	XP_006239367.1	Gene:	Ddi2 / 313668	RGDID:	1311815	Length:	986	Species:	Rattus norvegicus

Alignment Length:	400	Identity:	195/400 - (48%)
Similarity:	263/400 - (65%)	Gaps:	26/400 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 FCLDVAQDLELENLKALCAMEIGAEVSQIAVIFNGRELSSDKQTLQQCGVGDGDFIMLERRRSAN 77
            |.|.|..|.||.|.:|||.:|.|...::..:::..|.|:.:.::|...|:.|||.::|.::.:|:
  Rat    17 FSLQVDADFELHNFRALCELESGIPAAESQIVYAERPLTDNHRSLASYGLKDGDVVILRQKENAD 81

  Fly    78 -RPVGGNPAISTLDFSNIAVPGTSSGGSPPSRRVQQQGVQQPQFNNLTDIPTTDEFNVNFDDDPE 141
             ||......:..:|||:|||||||   :|..|::.:...|.......|..|       ...|.|.
  Rat    82 PRPSVQFSNLPRIDFSSIAVPGTS---NPQQRQLPRTQAQLLSPGERTSTP-------QGLDSPA 136

  Fly   142 TVRQMFLSSPETLSLLRQYNPSLAEAIDSGDKEKFARLLREHITERKRRNEHRMRMLNADPFDEE 206
            .:|.|.|::|..||||::.||.||||:.|||.|||:|:|.|...:|.||.:.|:|:.:|||||.|
  Rat   137 LLRDMLLANPHELSLLKERNPPLAEALLSGDLEKFSRVLVEQQQDRARREQERIRLFSADPFDLE 201

  Fly   207 TQRLIAEEIKQKNIQDNMAAAIEYNPEIFGTVTMLYINCKVNGIPVKAFVDSGAQTTIMSKDCAE 271
            .|..|.|:|:|:||::||..|:|..||.||.|.||||||:|||.|||||||||||.||||:.|||
  Rat   202 AQAKIEEDIRQQNIEENMTIAMEEAPESFGQVAMLYINCRVNGHPVKAFVDSGAQMTIMSQACAE 266

  Fly   272 RCHVNRLIDTRWNGVAKGVGTQPILGRIHMVQLQIENDHLTSSFTVLGQQPMDMLLGLDMLKRHQ 336
            ||::.||:|.||.|:|||||||.|:||:|:.|:|||.|.|..||::|.:||||||||||||||||
  Rat   267 RCNIMRLVDRRWAGIAKGVGTQKIIGRVHLAQVQIEGDFLACSFSILEEQPMDMLLGLDMLKRHQ 331

  Fly   337 CLIDLQRNLLIIGTTGTTTPFLPESELPVSARL---TGNS----EDSMEQEAISNAI-------E 387
            |.|||::|:|:|||||:.|.||||.|||..|||   ||..    |:..:|| ::.||       |
  Rat   332 CSIDLKKNVLVIGTTGSQTTFLPEGELPECARLAYGTGREDIRPEEIADQE-LAEAIQKSAEDAE 395

  Fly   388 QSKRESGGAG 397
            :|.:||...|
  Rat   396 KSSKESTSLG 405

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rngo	NP_001285328.1	UBQ	1..73	CDD:214563	20/59 (34%)
		DDI1_N	3..72	CDD:176391	20/58 (34%)
		RP_DDI	225..344	CDD:133146	82/118 (69%)
		UBA	411..445	CDD:279021
Ddi2	XP_006239367.1	UBQ	1..74	CDD:214563	19/56 (34%)
		DDI1_N	3..76	CDD:176391	20/58 (34%)
		RP_DDI	221..343	CDD:133146	84/121 (69%)
		CytochromB561_N	<387..>535	CDD:286826	5/18 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	185	1.000	Domainoid score	I3294
eggNOG	1	0.900	-	-		E1_KOG0012
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H121661
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D495103at33208
OrthoFinder	1	1.000	-	-		FOG0002352
OrthoInspector	1	1.000	-	-		otm44645
orthoMCL	1	0.900	-	-		OOG6_101685
Panther	1	1.100	-	-	O	PTHR12917
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1784
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.820