DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31773 and DFD

DIOPT Version :9

Sequence 1:	NP_722953.1	Gene:	CG31773 / 326159	FlyBaseID:	FBgn0051773	Length:	758	Species:	Drosophila melanogaster
Sequence 2:	NP_567026.3	Gene:	DFD / 824729	AraportID:	AT3G55630	Length:	492	Species:	Arabidopsis thaliana

Alignment Length:	535	Identity:	158/535 - (29%)
Similarity:	245/535 - (45%)	Gaps:	94/535 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   264 EKPEEKSPEHLAYLDAIKQLNSYQVLEPTSGRATTKSSRKEQDPVIEQTLECLEKSGLTKKDLKA 328
            |...|.|..:...|||:..|.:.:      ||..: :::..:..::...|:.||    .:..:..
plant     4 EDDGELSARYQNTLDALSSLITKR------GRLAS-NNQSHRFRLLFHYLKVLE----LEDAVSQ 57

  Fly   329 IPVIQVAGSKGRGSTCAIVESILRCHGVKTGVLSSPHLFLTSERIRIDGEPLSDVQFTELFW--- 390
            :.:|.|||:||:||||...||||||:|::||:.:||||....||.|::|..:|..:|...||
plant    58 MKIIHVAGTKGKGSTCTFAESILRCYGLRTGLFTSPHLIDVRERFRLNGIEISQEKFVNYFWCCF 122

  Fly   391 -KINTDLANMQPTPSYNKIMTVMAFHAFHQAGVEVAILEVGNAGASDATNIASHAQTIGITTLGW 454
             |:....:|..|.|:|...:.::||..|....|:|.|||||..|..||||:.......||::||:
plant   123 HKLKEKTSNEVPMPTYFCFLALLAFKIFTTEQVDVVILEVGLGGRFDATNVIQKPVVCGISSLGY 187

  Fly   455 EQSSNLGNSLRDIAWAKASIMKPEANIYTNVTQTECCEVLAQKAKQIGAQLRRVPTFNDYVEGDM 519
            :....||.:|.:||..||.|.|.....:|.....|...||.:||.::...|:.|...      |.
plant   188 DHMEILGYTLAEIAAEKAGIFKSGVPAFTVAQPDEAMRVLNEKASKLEVNLQVVEPL------DS 246

  Fly   520 NNKL-LMNKANYSMRLNGSLAVQLAYDFLK-------------RHKPE-YVVGLEHNSTLLTPGA 569
            :.:| |..:..|   ||..|||.|...|||             ...|| ::.||. |:.|:  |.
plant   247 SQRLGLQGEHQY---LNAGLAVALCSTFLKEIGIEDKNGLDQTNGLPEKFISGLS-NAYLM--GR 305

  Fly   570 SRGIEIFEQPGHFDFMRHDMFNVYLDSADTFESMMACRDWFYTRTRAN------RQPKILLFNKV 628
            :..:...|.|....:        |||.|.:.|||.||..||..:.:.|      |..:|||||.:
plant   306 AMIVPDSELPEEIVY--------YLDGAHSPESMEACAIWFSKQIKQNQERNQKRSEQILLFNCM 362

  Fly   629 NEFNAKDLLTIIRS-----NLRFEEACFVPNPNYFEG-----------EILAEEDGKAMVWHGME 677
            :..:...||..:||     .:.|:.|.||||.:.:..           |.::.:.|...:|   |
plant   363 SVRDPSLLLPRLRSKCIDQGVDFKRAVFVPNVSVYNQVGSSTNVGTRVESMSWQFGLQRIW---E 424

  Fly   678 ELQR--AKRNAGNWRALCEENGKRDN-----SQLSISINAFFEYLTNKYGKQKYGMKNELDVLVT 735
            .|.|  ||.|:.:     :..||.:.     |.|.:::    ::|.:...:.|   :....||||
plant   425 SLARGEAKSNSKS-----DSKGKEEEKSFVFSSLPVAV----DWLRDNARQSK---QVRFQVLVT 477

  Fly   736 GSRQLVAATISCLRK 750
            ||..||...:..::|
plant   478 GSLHLVGDLLRFIKK 492

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31773	NP_722953.1	folC	309..745	CDD:273659	148/483 (31%)
DFD	NP_567026.3	PLN02881	1..492	CDD:215476	157/533 (29%)
DFD	NP_567026.3	Mur_ligase_M	63..267	CDD:285457	80/212 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0285
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	243	1.000	Inparanoid score	I1065
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D840266at2759
OrthoFinder	1	1.000	-	-		FOG0001698
OrthoInspector	1	1.000	-	-		mtm1059
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11136
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2113
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	9	8.930