DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31773 and SPBC1709.17

DIOPT Version :9

Sequence 1:	NP_722953.1	Gene:	CG31773 / 326159	FlyBaseID:	FBgn0051773	Length:	758	Species:	Drosophila melanogaster
Sequence 2:	NP_595450.1	Gene:	SPBC1709.17 / 2540103	PomBaseID:	SPBC1709.17	Length:	505	Species:	Schizosaccharomyces pombe

Alignment Length:	520	Identity:	145/520 - (27%)
Similarity:	221/520 - (42%)	Gaps:	81/520 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   270 SPEHLAYLDAIKQLNSYQ----VLEPTSGRATTKSSRKEQDPVIEQTLECLEKSGLTKKDLKAIP 330
            :|:...:..||.:|||.|    |||....|....:.:...:  :...|.|:   |....||..:.
pombe    21 NPQTKTFEGAINRLNSLQSNAKVLEVLRKRGKIPNDQSMVE--MRHWLRCI---GYQPSDLNRLN 80

  Fly   331 VIQVAGSKGRGSTCAIVESIL------------RCHGVKTGVLSSPHLFLTSERIRIDGEPLSDV 383
            ||.|||:||:|||||...|||            :|.|:.|    ||||....|||:::|:|:|..
pombe    81 VIHVAGTKGKGSTCAFTSSILQQIQKSGERSIPKCIGMYT----SPHLRSVCERIQLNGKPISQE 141

  Fly   384 QFTELFWKINTDLANM----QPTPSYNKIMTVMAFHAFHQAGVEVAILEVGNAGASDATNIASHA 444
            .||:.|:.:...|.|.    ...|.|.:.:|:||:|.|....|:.||:|||..|..|:||:....
pombe   142 LFTKYFFDVWERLENAVGSDSEKPMYFRFLTLMAWHVFISENVDAAIIEVGIGGEYDSTNLIEKP 206

  Fly   445 QTIGITTLGWEQSSNLGNSLRDIAWAKASIMKPEANIYTNVTQTECCEVLAQKAKQIGAQLRRV- 508
            ....:|:||.:.:|.|||::.:|||.||.|.|..|...|.....|...||..:|.:....|:.|
pombe   207 YATAVTSLGLDHTSLLGNTIAEIAWQKAGIYKESAIALTCEQAPEAMNVLKNRAAERNTSLKVVI 271

  Fly   509 -PTFNDYVEGDMNNKLLMNKANYSMRLNGSLAVQLAYDFLKRHKPEYVVGLEHNSTLLTPGASRG 572
             |.   .:..||     :..:......|.||||.|..:|.::....:     .......|....|
pombe   272 PPA---ELTPDM-----IGLSGVHQLGNTSLAVSLVQEFYEKAGCPF-----DRDPYQDPAILDG 323

  Fly   573 IEIFEQPGHFDFMRHDMFNVYLDSADTFESMMACRDWFYTRTR--ANRQPKILLFNKVNEFNAKD 635
            ::..:.||.......:......|.|.|.||:.|...|..::..  .:...:|||||:.:.   .|
pombe   324 LKYVKWPGRCQIEEINNIKWCFDGAHTKESLEATGLWLASKKNLYEDADARILLFNQQSR---DD 385

  Fly   636 LLTIIRSNLR----------FEEACFVPNPNY----FEGEILAEE---DGKAMVWHGMEELQRAK 683
            .:.::||.|:          |....|..|..:    :..|:|:..   |.|. |.|..|:|.:.
pombe   386 PIALLRSFLKGLESSGTGISFTHVIFSTNVTWKDAGYNPELLSINTITDNKP-VLHVQEDLCKW- 448

  Fly   684 RNAGNWRALCEENGKRDNSQLSISINAFFEYLTNKYGKQKYGMKNELDVLVTGSRQLVAATISCL 748
                 |:   |..|....:.::.:|....|.:.:.  |||  .:|.. |.||||..|.......|
pombe   449 -----WK---ESKGTTSEATVAPTIQEAIETVMSI--KQK--SRNTF-VCVTGSLHLTGGVFVVL 500

Fly 749 748
pombe 501 500

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31773	NP_722953.1	folC	309..745	CDD:273659	133/472 (28%)
SPBC1709.17	NP_595450.1	FolC	34..482	CDD:223362	134/486 (28%)
SPBC1709.17	NP_595450.1	PEPCK_HprK	134..>181	CDD:304604	15/46 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0285
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001698
OrthoInspector	1	1.000	-	-		otm47296
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11136
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2113
TreeFam	1	0.960	-	-
	7	6.870