DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31773 and igcm-1

DIOPT Version :9

Sequence 1:	NP_722953.1	Gene:	CG31773 / 326159	FlyBaseID:	FBgn0051773	Length:	758	Species:	Drosophila melanogaster
Sequence 2:	NP_508166.1	Gene:	igcm-1 / 180433	WormBaseID:	WBGene00018215	Length:	1073	Species:	Caenorhabditis elegans

Alignment Length:	287	Identity:	57/287 - (19%)
Similarity:	101/287 - (35%)	Gaps:	79/287 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   165 SAAPKTQASWQQKVEKSAENE-DSGAFKGASSESQRKNWMNRMQGSQQRKQNQWLKEMQAKQQAG 228
            ||.|:.:..|..:..:.:||| .|....|.:.:......:.:::..|:....:::  .:|....|
Worm   657 SARPEPEFHWMFRDSEISENERHSFHTVGITGKPDEYEQLLQIESVQESDYGEYV--CRATNGNG 719

  Fly   229 KDIQAQKMQKMESQKATTTPAAPPKEAAPSTPQPAEKPEEKS--------PEHLAYLDAIKQLNS 285
            .|....:::|       |:|        |:.|...:|....|        |:.....|....|.:
Worm   720 GDHVVIELRK-------TSP--------PALPLDLQKLSATSNSVLLGWVPQFDGGADQTYVLET 769

  Fly   286 YQVLEPTSGR-------ATTKSSRKEQDPVIEQTL---ECLEKSGLTKKDLKAIPV------IQV 334
            .:: :|.:|.       :....:..:||..|:.||   .....:|||       |:      ||.
Worm   770 RKI-DPFTGEIDGNAPVSKLNINAVQQDQEIDGTLVSKNIFNFTGLT-------PLSTYNLRIQA 826

  Fly   335 AGSKGR--------GSTCAIVESILRCHGVKTGVLSSPHLFLTSERIRIDGEPL--SDV-----Q 384
            ...||.        .||..:||.        ..::|...|.|.|...:|:.||.  ||.     .
Worm   827 VSEKGESEFTPVLIASTEDVVED--------ANMMSPSRLVLDSSEQKINVEPKLPSDACTLLYV 883

  Fly   385 FTELFWKINT------DLANMQPTPSY 405
            |.:..|:.:|      .:.|:.|...|
Worm   884 FLDGIWRTSTCHTSSNPIGNIIPGREY 910

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31773	NP_722953.1	folC	309..745	CDD:273659	30/127 (24%)
igcm-1	NP_508166.1	Ig	45..119	CDD:299845
		Ig	146..226	CDD:299845
		Ig_3	245..316	CDD:290638
		IG_like	258..329	CDD:214653
		IG_like	338..398	CDD:214653
		IGc2	347..398	CDD:197706
		Ig_2	429..513	CDD:290606
		IG_like	437..513	CDD:214653
		Ig	537..615	CDD:143165
		IG_like	644..728	CDD:214653	13/72 (18%)
		IGc2	646..719	CDD:197706	11/63 (17%)
		FN3	733..843	CDD:238020	22/117 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3515
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900