Protein Alignment CG31759 and ANGEL2

DIOPT Version :9

• Sequence 1: NP_723735.2
• Gene: CG31759 / 326158
• FlyBaseID: FBgn0051759
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_653168.2
• Gene: ANGEL2 / 90806
• HGNCID: 30534
• Length: 544
• Species: Homo sapiens
• Alignment Length: 475
• Identity: 117/475 - (24%)
• Similarity: 181/475 - (38%)
• Gaps: 162/475 - (34%)

  Fly   208 NSAVQESPGRCPFQDRQRH-----------------TTNSLSESN------------EIRVVSYN 243
            :|.|..:.|..|...|::|                 .|..|.:.|            :..|:|||
Human   109 SSYVMNAEGDEPSSKRRKHQGVIKRNWEYICSHDKEKTKILGDKNVDPKCEDSENKFDFSVMSYN 173

  Fly   244 LLA-DLYASSDYAGSTLFSYCPAKYLQIDYRKPLFINEIIGYNSDILCLQEVDQRIFDFDLKEIL 307
            :|: ||...:    |.|:.:|....|...:|.|..:.||..:::|:||||||.:..:..:::..|
Human   174 ILSQDLLEDN----SHLYRHCRRPVLHWSFRFPNILKEIKHFDADVLCLQEVQEDHYGAEIRPSL 234

  Fly   308 EQPPYNYHGIMAPKGKCAEGVAIFFRNSRFDLLDSQILHLGSNIPALPVFE---SLWNKIKVNAQ 369
            |...|:....|. .|:..:|.||.|::|:|.||         ::..:..|.   ||.::..|...
Human   235 ESLGYHCEYKMR-TGRKPDGCAICFKHSKFSLL---------SVNPVEFFRPDISLLDRDNVGLV 289

  Fly   370 LAERICERSTTLQTCLLRIKGTDNYVLVANTHLYFHPDADHIRLLQMGFSMLFVEQSISKAIKDF 434
            |   :.:.......|        ..:.||||||.::|....|:|.|:  :||..|
Human   290 L---LLQPKIPYAAC--------PAICVANTHLLYNPRRGDIKLTQL--AMLLAE---------- 331

  Fly   435 NISS--HKNIG----LIFCGDFNSVPECGIY------KLMTEQL--------------------- 466
             |||  |:..|    ::.||||||||...:|      ||..|.|
Human   332 -ISSVAHQKDGSFCPIVMCGDFNSVPGSPLYSFIKEGKLNYEGLPIGKVSGQEQSSRGQRILSIP 395

  Fly   467 ---------------------AEKTLEDWQS----------NAEQAVSNVELAQPFKMASAY--- 497
                                 .|||..|...          .||:..||  |...|.::|.|
Human   396 IWPPNLGISQNCVYEVQQVPKVEKTDSDLTQTQLKQTEVLVTAEKLSSN--LQHHFSLSSVYSHY 458

  Fly   498 ----GAPEYTHYTTLFAGCLDYVFYQNDRFEV-------------LKV---VPLPTEEELKANTA 542
                |.||.|...:..|..:||:||..::.:|             ||:   :.|.||::|.....
Human   459 FPDTGIPEVTTCHSRSAITVDYIFYSAEKEDVAGHPGAEVALVGGLKLLARLSLLTEQDLWTVNG 523

  Fly   543 IPSAVFPSDHVALVADLKFK 562
            :|:....|||:.|:|  ||:
Human   524 LPNENNSSDHLPLLA--KFR 541

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31759	NP_723735.2	EEP	239..561	CDD:294334	106/412 (26%)
ANGEL2	NP_653168.2	EEP	169..542	CDD:321002	108/415 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5239
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D724242at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.820