Protein Alignment CG31759 and LRRC27

DIOPT Version :10

• Sequence 1: NP_723735.2
• Gene: CG31759 / 326158
• FlyBaseID: FBgn0051759
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_085129.1
• Gene: LRRC27 / 80313
• HGNCID: 29346
• Length: 530
• Species: Homo sapiens
• Alignment Length: 234
• Identity: 48/234 - (20%)
• Similarity: 71/234 - (30%)
• Gaps: 96/234 - (41%)

  Fly   327 GVAIFFRNSRFDLLDS--------------QILHLGSN------------IPALPVFESLWNKIK 365
            |..||..:...||.:|              |.|||..|            :|.|...:..:|:||
Human    40 GGIIFSSSPILDLSESGLCRLEEVFRIPSLQQLHLQRNALCVIPQDFFQLLPNLTWLDLRYNRIK 104

  Fly   366 -------VNAQLAERICERS------------TTLQTCLLRIKGTDNYVLVANTHLYFHPDADHI 411
                   .:..|...:.||:            |||:...||           :..|.|.|..
Human   105 ALPSGIGAHQHLKTLLLERNPIKMLPVELGSVTTLKALNLR-----------HCPLEFPPQL--- 155

  Fly   412 RLLQMG-------FSMLFVEQSISK--------AIKDFNISSHKNIGLIFCGDFNS--------V 453
             ::|.|       ..|..||.|:.:        .:::..:....:.||...||..|        .
Human   156 -VVQKGLVAIQRFLRMWAVEHSLPRNPTSQEAPPVREMTLRDLPSPGLELSGDHASNQGAVNAQD 219

  Fly   454 PECGIYKLMTEQL--AEK-----------TLEDWQSNAE 479
            ||..:.|.....|  .||           :.|:|.|..|
Human   220 PEGAVMKEKASFLPPVEKPDLSELRKSADSSENWPSEEE 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31759	NP_723735.2	EEP	239..561	CDD:469791	48/234 (21%)
LRRC27	NP_085129.1	LRR 1	46..67		3/20 (15%)
		LRR	<49..>155	CDD:443914	24/116 (21%)
		leucine-rich repeat	49..68	CDD:275378	3/18 (17%)
		LRR 2	68..89		5/20 (25%)
		leucine-rich repeat	69..92	CDD:275378	5/22 (23%)
		LRR 3	92..113		4/20 (20%)
		leucine-rich repeat	93..115	CDD:275378	4/21 (19%)
		LRR 4	115..136		3/20 (15%)
		leucine-rich repeat	116..138	CDD:275378	3/21 (14%)
		LRR 5	138..159		7/35 (20%)
		leucine-rich repeat	139..150	CDD:275378	3/21 (14%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	178..215		5/36 (14%)
		PTZ00121	<225..496	CDD:173412	8/34 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	402..432