DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG31759 and angel2

DIOPT Version :9

Sequence 1:NP_723735.2 Gene:CG31759 / 326158 FlyBaseID:FBgn0051759 Length:564 Species:Drosophila melanogaster
Sequence 2:NP_001025131.1 Gene:angel2 / 562704 ZFINID:ZDB-GENE-030131-6498 Length:569 Species:Danio rerio


Alignment Length:555 Identity:109/555 - (19%)
Similarity:184/555 - (33%) Gaps:198/555 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly   142 QIQFGERQFS--KAVWFKAKKPTD----TDWEVCGEGFQYLVTPEDIGYHLKFVVTPGNALGMTG 200
            |:|.....||  :..:.:..:|.|    :.|...|      |.|...|.||              
Zfish    62 QLQHPSSSFSTVRHPFNRPPRPPDPYQWSSWRQTG------VLPHTRGLHL-------------- 106

  Fly   201 PVVEKITNSAVQESPGRCPFQDRQRHTTNSLSESN------------------------------ 235
                   ::.:.||..|.|.|.|::.....:|:.:                              
Zfish   107 -------SAGLMESTDRPPPQKRRKSAEGEISQRSPQHSPPKGSRSPKGSPEWLRNVSSIEVANR 164

  Fly   236 ---------------------------------EIRVVSYNLLA-DLYASSDYAGSTLFSYCPAK 266
                                             :..|:|||:|: ||...:.|    |:.:|...
Zfish   165 TSAVPELKRHWEDLSHLCKAAPSVNRGKQKWPFDFSVMSYNILSQDLLCDNTY----LYRHCNPP 225

  Fly   267 YLQIDYRKPLFINEIIGYNSDILCLQEVDQRIFDFDLKEILEQPPYNYH-GIMAPKGKCAEGVAI 330
            .|....|.|..|.|:..|::||:|||||.:..:...:|..||.  ..|| ......|...:|.|:
Zfish   226 VLDWRNRFPNIIKELEQYSADIMCLQEVQEDHYKQQIKPSLES--LGYHCEFKRRTGLKPDGCAV 288

  Fly   331 FFRNSRFDLLDSQ-ILHLGSNIPALPVFESLWNKIKVNAQLAERICERSTTLQTCLLRIKGTDNY 394
            .|:..||.|:... :.:....:|       |.::..|...:..|..:...:|..           
Zfish   289 IFKRERFSLVSCHPVEYFRRGVP-------LMDRDNVGLIVLLRPIDPHVSLSN----------- 335

  Fly   395 VLVANTHLYFHPDADHIRLLQMGFSMLFVEQSISKAIKDFNISSHKNIGLIFCGDFNSVPECGIY 459
            :.||||||.::|....|:|.|:  :||..|.|....:.|.::..     ::.||||||||...:|
Zfish   336 ICVANTHLLYNPRRGDIKLAQL--AMLLAEISRVSQLPDSSVCP-----VLLCGDFNSVPWSPLY 393

  Fly   460 KLMTE---------------------------------------------QLAEKTLEDWQSNAE 479
            :.:.:                                             |..:..|.|.:....
Zfish   394 RFIKDRRLDYDGMPIGKVSGQEETPRGQRILTVPIWPRSLGISQQCQYENQTRDSELRDLEQTER 458

  Fly   480 QAVSNVELAQPFKMASAY-------GAPEYTHYTTLFAGCLDYVFYQ----------------ND 521
            ::.:...:....::.|||       |.||.|...:..|..:||:||.                ..
Zfish   459 ESFTEASIEHCLRLTSAYSHHLKESGQPEITTCHSRTAITVDYIFYSAALGDVMAQAEYSAPPER 523

  Fly   522 RFEVLKVVPLPTEEELKANTAIPSAVFPSDHVALV 556
            ..::|..:.|..|:||:....:|:....|||:.|:
Zfish   524 GLQLLGRLALVGEKELQKVNGLPNQHNSSDHLPLL 558

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG31759NP_723735.2 EEP 239..561 CDD:294334 89/389 (23%)
angel2NP_001025131.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..22
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 63..92 5/28 (18%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 109..155 7/45 (16%)
EEP 201..563 CDD:294334 89/389 (23%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5239
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D724242at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
32.820

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