Protein Alignment CG31759 and ANGEL1

DIOPT Version :9

• Sequence 1: NP_723735.2
• Gene: CG31759 / 326158
• FlyBaseID: FBgn0051759
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_001357675.1
• Gene: ANGEL1 / 23357
• HGNCID: 19961
• Length: 744
• Species: Homo sapiens
• Alignment Length: 463
• Identity: 96/463 - (20%)
• Similarity: 185/463 - (39%)
• Gaps: 78/463 - (16%)

  Fly    40 EPIDAILARIQSNIIGRLAKSCKKSKI--KPPAEINVKLLSDKYGEKFNELTFEDLVVTQDISNV 102
            |..:.:|.:.:...:.::..:..:..:  |..|:.::.||.|..||:  ....||...::.:|::
Human    55 EECEGLLQQWREEGLSQVLSTASEGPLIDKGLAQSSLALLMDNPGEE--NAASEDRWSSRQLSDL 117

  Fly   103 K-LQVLDTVYDLVFNPPWISSLKFLPSCILAGFVIYPTNVQIQFGERQFSKAVWFKAKKPTDTDW 166
            : .:.||..:..:.....:..::.:...:.|.       :.:| .|.|::..............|
Human   118 RAAENLDEPFPEMLGEEPLLEVEGVEGSMWAA-------IPMQ-SEPQYADCAALPVGALATEQW 174

  Fly   167 EVCGEGFQYLVTPEDIGYHLKFVVTPGNALGMTGPVVEKITNSAVQESPGRCPFQD---RQRHTT 228
            |.......:.:.||.:... :..:.|...||...|...:|            |:.:   |:....
Human   175 EEDPAVLAWSIAPEPVPQE-EASIWPFEGLGQLQPPAVEI------------PYHEILWREWEDF 226

  Fly   229 NSLSESNEIR----------VVSYNLLA-DLYASSDYAGSTLFSYCPAKYLQIDYRKPLFINEII 282
            ::..::..::          ::|||:|| ||...|    |.|:.:|....|..:||....:.|..
Human   227 STQPDAQGLKAGDGPQFQFTLMSYNILAQDLMQQS----SELYLHCHPDILNWNYRFVNLMQEFQ 287

  Fly   283 GYNSDILCLQEVDQRIFDFDLKEILEQPPYNYHGIMA----PKGKCAEGVAIFFRNSRFDLLDSQ 343
            .::.||||||||.:   |...:::  :|.....|...    ..|...:|.|:.::.:||.||.:.
Human   288 HWDPDILCLQEVQE---DHYWEQL--EPSLRMMGFTCFYKRRTGCKTDGCAVCYKPTRFRLLCAS 347

  Fly   344 ILHLGSNIPALPVFESLWNKIKVNAQLAERICERSTTLQTCLLRIKGTDNY--VLVANTHLYFHP 406
            .:....  |.|    .|.|:..|...|         .||..:....|..:.  :.|||||:.::|
Human   348 PVEYFR--PGL----ELLNRDNVGLVL---------LLQPLVPEGLGQVSVAPLCVANTHILYNP 397

  Fly   407 DADHIRLLQMGFSMLFVEQSISKAIKDFNISSHKNIGLIFCGDFNSVPECGIYKLMTE-QLAEKT 470
            ....::|.||...:..|:       |...:|...:..:|.|||.||||:..:|..:.: :|....
Human   398 RRGDVKLAQMAILLAEVD-------KVARLSDGSHCPIILCGDLNSVPDSPLYNFIRDGELQYHG 455

  Fly   471 LEDWQSNA 478
            :..|:|.|
Human   456 MPAWKSLA 463

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31759	NP_723735.2	EEP	239..561	CDD:294334	67/248 (27%)
ANGEL1	NP_001357675.1	EEP	248..>449	CDD:351117	63/231 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5239
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810