Protein Alignment CG31759 and pde-12

DIOPT Version :10

• Sequence 1: NP_723735.2
• Gene: CG31759 / 326158
• FlyBaseID: FBgn0051759
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_499388.1
• Gene: pde-12 / 176514
• WormBaseID: WBGene00011268
• Length: 628
• Species: Caenorhabditis elegans
• Alignment Length: 606
• Identity: 151/606 - (24%)
• Similarity: 266/606 - (43%)
• Gaps: 107/606 - (17%)

  Fly    15 LDIVFRFVN--ENLKINREFNFRRQMNEPIDAILARIQSNIIGRLAKSCKKSKIKPPAE-INVKL 76
            |:.:|:|.:  |:..|..:..|.:::   :|..|.:|.       |...|||:.:...| |:::|
 Worm    69 LNFMFQFNHGEEHFVIKTQRAFEQKL---VDEALPKIS-------ALMRKKSRTEASEEDISMQL 123

  Fly    77 LSDKYGEKFNELTFEDLVVTQDISNV-KLQVLDTVYDLVFNPPWISSLKFLPSCILAGFV----- 135
            .::  .|.|.::..:..:...|...: ||.|..:.::::.|...||::....:.|:..|.
 Worm   124 AAE--FENFKDINLKTTLEFADDKRISKLLVNGSEFEVIRNGIPISTVSITLTPIVGQFCMPTIA 186

  Fly   136 --IYPTNVQIQFGERQFSKAVWF--------KAKK--PTDTD---------------WEVCGEGF 173
              |..|.||:.          ||        |::|  ||..|               :::.|..|
 Worm   187 YNIKGTRVQLH----------WFVKDQKETGKSEKLGPTQKDNDSLKLAFEDEAARTFKLHGYSF 241

  Fly   174 Q----YLVTPE-DIGYHLKFVVTPGNALGMTGPVVEKITNSAVQESPGRCPFQDRQRHTTN-SLS 232
            :    |....| |:...:..||..|.    ..|....|::..:.:........::.:.... ||.
 Worm   242 RHSGPYFQPDEKDVSRLVAVVVESGK----DHPAYAAISSRPISQLHDEVITDEQVKWCEEISLE 302

  Fly   233 ESNEIRVVSYNLLADLYASSDYAGSTL-FSYCPAKYLQIDYRKPLFINEIIGYNSDILC----LQ 292
            :.:.||::|||:|||||.:.......| |:||.....:|.||.|:|:.::..:.....|    ||
 Worm   303 DDSTIRIMSYNILADLYLNLTLPQEQLFFNYCQKSSQRIIYRTPIFLKQLHDFIHSARCSLIFLQ 367

  Fly   293 EVDQRIFDFDLKEILEQPPYNYHGIMAPK-GKCAEGVAIFFRNSRFDLLDSQ---ILHLGSNIPA 353
            |||....:..:...|.  ..:|...:|.| |..:|||||.|.:.||.::.|:   :..|.|.
 Worm   368 EVDLSRHENFIVPFLN--TISYSSEIAKKVGTVSEGVAIIFDSQRFQVISSKCYGVAELASG--- 427

  Fly   354 LPVFESLWNKIKVNAQLAERICERSTTLQTCLLRIKGTDNYVLVANTHLYFHPDADHIRLLQMGF 418
                 .:...::.:.:..||...|.|.||..:|:...|...::..||||:.:|..:|:::||
 Worm   428 -----DILGILETSEESKERFSTRPTVLQIVVLKDSRTGKLLVCGNTHLHHNPIDEHVKVLQ--- 484

  Fly   419 SMLFVEQSISKAIKDFNISSHKNIGL----IFCGDFNSVPECGIYKLMTEQLAEKTLEDWQSNAE 479
                ......|.::.:..:...|.|:    :|.|||||.|...::.||:  :.....||...|.:
 Worm   485 ----ALTCTRKLLEIYEETRELNKGIEVLVLFGGDFNSTPNGAVFNLMS--MGNLPKEDAVWNCD 543

  Fly   480 QAVSNVELAQPFKMASAYGAPEYTHYTTL-----FAGCLDYVFYQNDRFEVLKVVPLPTEEELKA 539
            ..::..::....||....|.||||:||..     |.|||||::  ......::..|||:.|::..
 Worm   544 SKITPQDIKIDKKMDCLTGTPEYTNYTASSQKDGFVGCLDYIW--GVGATSIRHCPLPSHEKVIK 606

  Fly   540 NTAIPSAVFPSDHVALVADLK 560
            .||:||.:.||||:.::.|:|
 Worm   607 YTALPSPISPSDHLPIICDIK 627

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31759	NP_723735.2	EEP	239..561	CDD:469791	99/340 (29%)
pde-12	NP_499388.1	EEP	309..628	CDD:469791	99/340 (29%)