Protein Alignment mon2 and garz

DIOPT Version :9

• Sequence 1: NP_001033884.2
• Gene: mon2 / 326157
• FlyBaseID: FBgn0031985
• Length: 1684
• Species: Drosophila melanogaster
• Sequence 2: NP_610761.2
• Gene: garz / 36337
• FlyBaseID: FBgn0264560
• Length: 1983
• Species: Drosophila melanogaster
• Alignment Length: 1750
• Identity: 318/1750 - (18%)
• Similarity: 565/1750 - (32%)
• Gaps: 587/1750 - (33%)

  Fly    11 GQDVHKFVEALQADFKTLSLETKKKYPQIKEACEEAISKLCTAGSSQ----------QNSVYYTV 65
            |:|     |....:...:.:|:.:..|.:.....||.|.|..|.||:          |.|..:.|
  Fly   298 GED-----ETTVPETPVIQVESTESEPLLDGETGEATSTLAEANSSEYINSVGVRFTQQSTDHDV 357

  Fly    66 NQIL---YPLVQGCETKDLKIIKFCLGMMQRLITQ--QVVDQKGALYITNALWTLMEN------N 119
            ..:.   .|.:|       ::.:|.:.:...|..|  ..:...|...:|.|.....:|      .
  Fly   358 TSLSPYGLPFIQ-------ELFRFLIILCNPLDKQNSDSMMHTGLSLLTVAFEVAADNIGKYEGL 415

  Fly   120 IEEVK--VLQTVTLLLTTNTVVHGDTLAKALVLCFRLHYAKNPTIVNTAGATIRQLVSLV----- 177
            :|.||  :.:.:..||::..:   ...|..|.|||.|..:....:.....|.:|:|..::
  Fly   416 LELVKDDLCRNLISLLSSERL---SIFAADLQLCFLLFESLRGHLKFQLEAYLRKLSEIIASDNP 477

  Fly   178 ---FERVYLEKDSVSSLQQQQSSGSPAEGEGGNQDVQTFASDAF-----LLFQDLVQLVNADQPY 234
               :|...|..|::  ||..:..|...| ...|.|...:.:|.|     ||.:..:...||....
  Fly   478 KTPYEMRELALDNL--LQLWRIPGFVTE-LYINYDCDLYCTDMFESLTNLLSKYTLSATNAVYST 539

  Fly   235 WLLGMTEMTRTFGLELLEAVLTNFSAVFHESNDFRLLLKERVCALVIKLFSPNVKHRQLPAPSNG 299
            .::.|..:     |.:::::..|.:|..:.||: |..|.|...|......|.:....:.....:|
  Fly   540 HIISMDTL-----LSVIDSIERNCAASKNSSNN-RESLPEAAPATGGSRHSRHNSGLEGIVIDSG 598

  Fly   300 NAPVPAEK-----PYFPISMRLLRL-------------VAILIQK-------------------- 326
            |:....||     .:...|...|||             :|.:.||
  Fly   599 NSVAAEEKVENIASFINASSHRLRLQSGGEGVGITSEQLAKVKQKKRLLSQGTERFNQRPEKGIQ 663

  Fly   327 ---YHTILVTECEIFLSLIIKFLDP--------DKPAWQRALALEVIHKLV-TRSSLIAFFCKSY 379
               .|.||..|           |||        :.|...:.:..|.|.|.. ..|.::..|..|:
  Fly   664 YLQEHGILNAE-----------LDPMQVALFLRENPGLDKKMIGEYISKKKNVDSKILINFVDSF 717

  Fly   380 DLKNHATNIVHDMIAAMGSYIRYSLINASAML-------------NGQQNGVANSLTAMSGSNQC 431
            |.    |.:..|.  |:..|:....:...|.|             ...|:..||...|
  Fly   718 DF----TGLRVDQ--ALRLYLETFRLPGEAPLIFLVLEHFSDHWHKQNQDPFANVDAA------- 769

  Fly   432 GFMFRGAYLPLVATYAPGVSKAVYLEMLDKIDAS----NIP--------DSYGISVGHAILLDMT 484
               ||.||             |:.:..:|:.:::    |:|        :..|::.|.....:|.
  Fly   770 ---FRLAY-------------AIIMLNMDQHNSNAKRLNVPMTLEDFTKNLRGLNGGEDFDQEML 818

  Fly   485 RSIGGVIQRTPELHPSHNTAVITEEEHKPLCL--------------------QLVNSSWSALLSA 529
            ..:...|:....:.|:..|.::.|.....:.|                    ::.|..|.|.|||
  Fly   819 AQVFNAIKNEEIVMPAEQTGLVRENYQWKVLLRRGDTHDGHFHYVHDASYDVEIFNIVWGASLSA 883

  Fly   530 FIPLVETSIDEATTENILKAMQNYAALCGMLEQLQPRDAFIMAMCRASFPPHYAMSIFANTTQSD 594
            ...:.:.| .|...:..|......||:..........||.::.:|:.:       ::.::..|
  Fly   884 LSFMFDKS-TETGYQRTLAGFSKSAAISAHYNLHSDFDALVLTLCKFT-------TLLSSVEQ-- 938

  Fly   595 GDLRCHTRSGSQDLSSQFINSCSGDAGDFRPQIVAVGTPLPSASLPHSVMQAPVMLTNKNLQCMR 659
                 |..:.:.:.:.|.:|                                 ..|..|....||
  Fly   939 -----HEPAPANNETQQAVN---------------------------------FGLNGKAQAAMR 965

  Fly   660 AILFLAHNNGGILGTSW-HIVLQTLQHLVWILGLKP-----------STGGSLQAMPKPAVEANV 712
            .:..|.|:.|..|..|| ||:...||  ::.|.|.|           :.|.::..:.||..:...
  Fly   966 TVFLLVHDYGDCLRESWKHILDLYLQ--LFRLKLLPKSLIEVEDFCEANGKAMLILEKPREKQES 1028

  Fly   713 GIQTAVMADLPVLSQ---------------------MLSQLFESSQYLDDVALHHLIDALCKL-- 754
            |:.:::.:.:....|                     .|.|:.:.|:::...:|..|:..:..|
  Fly  1029 GLFSSLYSFISSEGQREPTYEEQDFIKLGRKCIKECQLDQMLQESKFVQLESLQELLKCVLALLK 1093

  Fly   755 ---SHEAMELAYANREPSLFAVAKLLETGLVNMPRIKVLWRPLTNHLLEV------CQHRHIRMR 810
               .|:::.|.|| .:.::|.:..|::..:.|..|:..||..:.:.:..:      |.:.::..|
  Fly  1094 APQGHKSIGLPYA-EDQTVFWMEFLVKIVVHNRDRMIPLWPAVRDQMYLLLMGSASCGYDYLLNR 1157

  Fly   811 EWGVEAITYLVKSALQFKHKTPLKENMELQTMLLSPLSELSTVLHADVRQ--RQLDC-VLQILNT 872
                 .|..::|.|:.      |..|.||..::|..|..|..:..|.:.:  :|:.. :.::|.|
  Fly  1158 -----CIVAVLKLAIY------LMRNEELCPIVLQSLKMLLMLKPALLLRISKQISIGIYELLKT 1211

  Fly   873 AGEIL--SFGWPAI---IEIIGA------------------------------------------ 890
            :.:.:  ...|..|   :|.:||
  Fly  1212 SAQNIHSEQDWQIIFNLLECVGAGAVPPNYDDAQLPLPPNGSAKSDGAISGEEDATAVPERGYTS 1276

  Fly   891 -----------------------VNEHHGE---------------PLIRT--------------A 903
                                   ||....|               |.:.|              .
  Fly  1277 DSEITKASAAPAVSSPSAENWILVNNKDSELTTASRPQSPPSLSAPPVNTLVYNCQLLDHAPFAL 1341

  Fly   904 FQC---LQLVITDFLTVMPW------RCLPL----C----------ISTAAK------------- 932
            |:|   |..::.....:.|:      ||:.:    |          :.:|||
  Fly  1342 FKCWDSLAFIVRSVAHITPYNFEACVRCIRIFVEACRDGGIRQRRKLESAAKQKSSKKRSERKPG 1406

  Fly   933 FGSQTQELNISLTAIGLMWNISDFFNQ------NQDKL------MSTQLQDVSILPDFPGTVK-- 983
            ..|.....|::|    |..:.||  ||      .|:.|      :|.||.|: :...:..|.:
  Fly  1407 MASSASSSNLTL----LTGDPSD--NQINGNAAEQEDLAQRYEQLSIQLLDL-MYTLYTRTAQIF 1464

  Fly   984 ---------MPQFDKLW---MC-LYAKLGELCVDLRPAVRKSAGQTLFS-TISAHG-SLLNPPTW 1033
                     :||...||   .| |...:..|.:|.|..||..|...|.. .:..|. ..|:...|
  Fly  1465 RWWAEEGCTVPQSAALWSPGWCPLLQGIARLAMDRRREVRTHAISCLQQRALLVHDLQTLSGTEW 1529

  Fly  1034 QALVWQVLFPLLDNVRALSSSASNEKVDASGNILIHHSRNTAQKQWAETQVLTLSGVCRVFNTKR 1098
            .:...|||||||:.:...|::|.  ::||:   |:..||           :.|.:.:.:||....
  Fly  1530 CSCFHQVLFPLLNELLPESNAAG--QLDAA---LLEESR-----------IRTATIMSKVFLQHL 1578

  Fly  1099 ELLQMLGD-FERAWSLILEFIQNAALSKNGEVSLAALKSLQEIM------------YHNTAERTE 1150
            ..|..||: |...|..||::|:.  ..|.|..:|:  :.:|||:            :||
  Fly  1579 TTLIELGNAFNELWLDILDYIER--FMKVGSDTLS--EQMQEILKNMLLVMHSVRVFHN------ 1633

  Fly  1151 RALKDPQTAQEQDEEIWTIAWNI-WLSIGMESTKMSTSTSAKLQQQNSNGAETQEDFYIPSQAFL 1214
                       ||..:....|.: |..||    :...:...:|.......|:|..: ..|..|..
  Fly  1634 -----------QDGSLQQALWELTWRRIG----EFLPNLKEELFHDEGKRAQTLTN-PAPQAAVA 1682

  Fly  1215 TALIQIFPAIFQHIQVKFTAADFDKFCTVLTN--------AVCIPVQTDAVPYIMSTV-----SD 1266
            .|..|..||:                 |:|..        .|..|....|.|.:.|.|     |.
  Fly  1683 AAPQQQLPAV-----------------TILPRQTQVSNELVVSAPTPPAATPLLGSPVESPRRSI 1730

  Fly  1267 TLLTPLHDGILDCMELIQKEAT-----------KPDSHISQLIPAIFRQLLIFSKFACAPPTFQQ 1320
            .|..|:.|       ::|:..:           :|.:....:.|:.....|:....|.|......
  Fly  1731 ILQPPMAD-------VLQQPPSFVFAQPIIVPPQPPAVTDPIPPSTLLPDLVNEATAAAVQATTT 1788

  Fly  1321 SVEH--KYAKSSGHYANNASVEVVSMNYIPFGEKSISICVKLY-QTTATEDSVVQEQILH 1377
            |..|  :.|:.........::...:..|     .|.:|.|.:. :|||.:....|:|:|:
  Fly  1789 SPTHSPQEAEQPASIVQQTNIVTTNNTY-----NSYAIEVPMAPETTAEQFGQQQQQLLY 1843

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mon2	NP_001033884.2	DCB	13..184	CDD:292830	38/201 (19%)
		Sec7_N	213..380	CDD:289549	42/221 (19%)
		DUF1981	827..909	CDD:286414	24/186 (13%)
		Mon2_C	912..1665	CDD:292823	117/568 (21%)
garz	NP_610761.2	COG5307	346..>1062	CDD:227623	144/824 (17%)
		Sec7_N	370..512	CDD:289549	30/147 (20%)
		Sec7	643..830	CDD:279680	38/226 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45452089
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10663
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030