Protein Alignment AspRS-m and MSD1

DIOPT Version :10

• Sequence 1: NP_001260520.2
• Gene: AspRS-m / 326155
• FlyBaseID: FBgn0051739
• Length: 1139
• Species: Drosophila melanogaster
• Sequence 2: NP_015221.1
• Gene: MSD1 / 856000
• SGDID: S000006025
• Length: 658
• Species: Saccharomyces cerevisiae
• Alignment Length: 676
• Identity: 215/676 - (31%)
• Similarity: 326/676 - (48%)
• Gaps: 150/676 - (22%)

  Fly   459 FADRTHNCGELTSNDINEKVVICGWLEF--QRMNK---FFILRDAYGQTQVLLSPKTYGLEEYAE 518
            |...|....:|......:|:|:.||:|.  :|:.|   |.:|||:.|....|:..|:      ..
Yeast    31 FRKDTSTIKQLKGLSSGQKIVLNGWIEQKPKRVGKNLIFGLLRDSNGDIIQLVDNKS------LL 89

  Fly   519 TGVPIESIVRVEGTVIPRPAATINPKM---QTGHVEVEADKVVVLNPAKKNLPFEIRKFNRAGER 580
            .|..:|.:|:..|.:      ::..|:   .....||:.:.:.|||.:.|. |.:::.|     :
Yeast    90 KGFTLEDVVQAVGIL------SLKRKLSNEDADEYEVQLEDITVLNASNKK-PAQMQDF-----K 142

  Fly   581 LRLTH----RYLDLRFNDMQHNLRLRSAVIMKMREYLINYLGFVEVETPTLFRRTPGGAQEFVVP 641
            |...:    |||.||....|..|:.||::..::|....|: .|.|||||.||:.||.||:||:||
Yeast   143 LSAIYPPEFRYLQLRNPKYQDFLKKRSSISKEIRNSFNNF-DFTEVETPMLFKATPEGAREFLVP 206

  Fly   642 TRK-----AGHFYSLVQSPQQFKQMLMSGGIDRYFQVARCYRDEATRPDRQPEFTQLDIELSFTS 701
            ||.     ...||:|.|||||:||:||:.|:::|:|:|||:|||..|.||||||||:|:|::|.:
Yeast   207 TRTKRSDGKPSFYALDQSPQQYKQLLMASGVNKYYQMARCFRDEDLRADRQPEFTQVDMEMAFAN 271

  Fly   702 RDDIMQLIEETLRYSWPK----------DFPRLQTPFR---------RITYEEAMEKYGNDKPDT 747
            .:|:|::||:|:...|.|          |......|.:         |:|||:||..||.||||.
Yeast   272 SEDVMKIIEKTVSGVWSKFSKKRGLLTLDSKGTLVPAKKENGTVSIFRMTYEQAMTSYGIDKPDL 336

  Fly   748 RFGFL-------------LNN---VSEII------EKSDEFKEKYDDLG-----AYAIVV----- 780
            |...|             ||.   |.|:|      ...:|:||::..|.     .|.:.:
Yeast   337 RAPDLKIINLGEFNAFSHLNKKFPVFEVIILRSAFSNMEEYKERWSFLTNNSNYNYRVPIVLPIE 401

  Fly   781 --RASEAFWNGAARKHYESLGKEFKGTLFVRKFGPTKDVQEKLGKLLGEDVATEVADKFDLEEND 843
              ..:.:.|    .:::.::. .|:....:.||     ::.|.|         ::......|.|.
Yeast   402 NDEQANSNW----FENFHAIA-TFENPHLITKF-----LKLKKG---------DIVCGCTREPNH 447

  Fly   844 LLFLGIGSKVETRELLGRIR-LDYQDFLVENAKIKKPNDFRFL------WVIDFPLFE------- 894
            .:|       |....|||:| |..|.   |:.|    |.:..:      |::|||||.
Yeast   448 SIF-------ENPTPLGRLRQLVLQS---EHGK----NIYHAVNKDVASWIVDFPLFSPVIIEDK 498

  Fly   895 ---------RNRETNQLESVHHPFTLPHSDDLENFATSCENLESIRSQAYDLVLNGQEVGGGSIR 950
                     ...|.::|.|.|||||:....|.|...   :..|....:.||||:||.|:||||.|
Yeast   499 SGKKEKLAYPEYEKDRLCSTHHPFTMVKLKDYEKLE---KTPEKCLGRHYDLVVNGVELGGGSTR 560

  Fly   951 IHDRDMQHFILEQILKI--PHDHLSHLLSALESGCPPHGGIALGLDRLIAILCRARSIRDVIAFP 1013
            |||..:|.:|.|.||||  .::...|||:|.:.|.|||.|.|:|.||:.|::|...|||||||||
Yeast   561 IHDPRLQDYIFEDILKIDNAYELFGHLLNAFDMGTPPHAGFAIGFDRMCAMICETESIRDVIAFP 625

  Fly  1014 KSLNGRDPLSNAPVPISDEEMRLYHL 1039
            ||:.|.|.:..:|..|.:..:..|::
Yeast   626 KSITGADLVVKSPSVIPESILEPYNI 651

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AspRS-m	NP_001260520.2	Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with oligonucleotide/oligosaccharide (OB) fold.	148..303	CDD:471953
		EcAspRS_like_N	291..410	CDD:239812
		aspS	462..1045	CDD:234775	214/673 (32%)
MSD1	NP_015221.1	aspS_bact	35..658	CDD:211576	214/672 (32%)