Protein Alignment AspRS-m and dars-2

DIOPT Version :10

• Sequence 1: NP_001260520.2
• Gene: AspRS-m / 326155
• FlyBaseID: FBgn0051739
• Length: 1139
• Species: Drosophila melanogaster
• Sequence 2: NP_506019.2
• Gene: dars-2 / 3565124
• WormBaseID: WBGene00001095
• Length: 593
• Species: Caenorhabditis elegans
• Alignment Length: 612
• Identity: 250/612 - (40%)
• Similarity: 371/612 - (60%)
• Gaps: 58/612 - (9%)

  Fly   452 KVADTNKFADRTHNCGELTSNDINEKVVICGWLEFQRMNKFFILRDAYGQTQVLLSPKTYGLEEY 516
            ::..|:.:..|||.|.||::::.||||.:.|||..:||::||:||||||..|..:|..: .|:..
 Worm    14 RILSTSSYTVRTHICDELSTSNKNEKVSVMGWLSHKRMDRFFVLRDAYGSVQAKISASS-KLQSL 77

  Fly   517 AETGVPIESIVRVEGTVIPRPAATINPKMQTGHVEVEADKVVVLNPAKKNLPFEIRKFNRAGERL 581
            .: .:|.||:|||:|.|:.| ....|.||:||.:|::.:::.|||.|..|:|. :...| |.||.
 Worm    78 LK-DIPYESVVRVDGIVVDR-GDNRNSKMKTGDIEIDVEELTVLNKATSNIPM-LPDAN-ANERT 138

  Fly   582 RLTHRYLDLRFNDMQHNLRLRSAVIMKMREYLINYLGFVEVETPTLFRRTPGGAQEFVV--PTRK 644
            ||.:||:|||.:.:|.:|||||..:..:|.:|:...|||:||||||||||||||.||||  |:..
 Worm   139 RLKYRYIDLRSDKLQKSLRLRSEFVHNVRRFLVEKSGFVDVETPTLFRRTPGGAAEFVVPAPSPN 203

  Fly   645 AGHFYSLVQSPQQFKQMLMSGGIDRYFQVARCYRDEATRPDRQPEFTQLDIELSFTSRDDIMQLI 709
            .|..|||.||||||||:||.|.||||||:|||||||.::.||||||||:|:|:|||:::.:||||
 Worm   204 QGLAYSLPQSPQQFKQLLMVGAIDRYFQIARCYRDEGSKGDRQPEFTQVDVEMSFTTQNGVMQLI 268

  Fly   710 EETLRYSWPKDFPRL--QTPFRRITYEEAMEKYGNDKPDTRFGFLL----NNVSEIIEKSDEFKE 768
            |:.:..:||:....:  ::||.||.|.:||..||.||||.|..:.:    |::.|.::|..:
 Worm   269 EDMIISAWPESLNHIKPKSPFPRIPYSDAMRLYGIDKPDMRIPWQIDDVDNDIFEFLQKDID--- 330

  Fly   769 KYDDLGAYAIVVRASEAFWNGAARKHY-ESLGKEFKGTLFVRKFGPTKDV----QEKLGKLLGED 828
              ||.....|:|      ..||.:... .|:..|:|..:.:.:.|....:    |::..|.....
 Worm   331 --DDTWRSRILV------CRGAGKTTISNSMKNEWKRLIQMNENGKNFAICHPSQKRWFKPFDNQ 387

  Fly   829 VATEVADKFDLEENDLLFLGIGSK---VETRELLGRIRLDYQDFLVENAKIKKPNDFRFLWVIDF 890
               ::.|:|.|.:.|:|.:..|:.   ..|.|:.|               ::..::....|::||
 Worm   388 ---KLIDQFGLIDEDVLIVCWGNSEGVYWTLEVCG---------------LRSKSNVTAHWIVDF 434

  Fly   891 PLFERNRETNQLESVHHPFTLPHSDDLE-NFATSCENLESIRSQAYDLVLNGQEVGGGSIRIHDR 954
            |||  :.|..||.|.|||||.|...|:: .::...:.|..|..|.||||:||.|:|||||||.:.
 Worm   435 PLF--SFEEGQLVSTHHPFTAPLEKDIDILYSNDIDKLLQITGQHYDLVINGVEMGGGSIRIENS 497

  Fly   955 DMQHFILEQILKIPHDHLSHLLSALESGCPPHGGIALGLDRLIAILCR----ARSIRDVIAFPKS 1015
            ::|..:| ::|..|.|.:.|||:||..|.|||||.||||||.:|:|..    ...:||||||||:
 Worm   498 EIQRHVL-KVLGEPTDEMEHLLNALSHGAPPHGGFALGLDRFVAMLTSDGNPLTPVRDVIAFPKT 561

  Fly  1016 LNGRDPLSNAPVPISDEEMRLYHLSVV 1042
            .||:|.:|:||..:|.:::..|.:|::
 Worm   562 KNGKDLMSDAPATLSQKQLERYGISLL 588

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AspRS-m	NP_001260520.2	Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with oligonucleotide/oligosaccharide (OB) fold.	148..303	CDD:471953
		EcAspRS_like_N	291..410	CDD:239812
		aspS	462..1045	CDD:234775	249/602 (41%)
dars-2	NP_506019.2	AspS	24..593	CDD:439943	249/602 (41%)