Protein Alignment AspRS-m and dar2

DIOPT Version :10

• Sequence 1: NP_001260520.2
• Gene: AspRS-m / 326155
• FlyBaseID: FBgn0051739
• Length: 1139
• Species: Drosophila melanogaster
• Sequence 2: NP_587777.1
• Gene: dar2 / 2538918
• PomBaseID: SPCC736.06
• Length: 611
• Species: Schizosaccharomyces pombe
• Alignment Length: 622
• Identity: 233/622 - (37%)
• Similarity: 342/622 - (54%)
• Gaps: 76/622 - (12%)

  Fly   474 INEKVVICGWL-----EFQRMNKFFILRDAYGQTQVLLSPKTYGLEEYAE--------------- 518
            :..||.|.|||     :..:...|..|||.:|....|||.....|::..|
pombe    14 VGTKVSIQGWLVATSRQVSKSISFHQLRDTHGTILQLLSTDKIILQQKREPLVSSTDFSQQKSTS 78

  Fly   519 -----TGVPIESIVRVEGTVIPRPAATINPKMQTGHVEVEADKVVVLNPAKKNLPFEIRKF---N 575
                 :.:|.||:|:|.|.:..||.....|   ....|:..:.|.:||.||     .::.|   .
pombe    79 VMRTLSSIPPESVVQVTGKLQRRPEHDRRP---GNEFELHVEDVKLLNVAK-----NLQLFPGDE 135

  Fly   576 RAGERLRLTHRYLDLRFNDMQHNLRLRSAVIMKMREYLINYLGFVEVETPTLFRRTPGGAQEFVV 640
            :.|.|::|.:|::.||.......||.||.:..::..: .|...|.|||||.||:.||.||:||||
pombe   136 KPGMRIQLANRHIQLRAPKYNSYLRQRSRLAYQVHSF-FNDREFCEVETPLLFKSTPEGAREFVV 199

  Fly   641 PTR-KAGHFYSLVQSPQQFKQMLMSGGIDRYFQVARCYRDEATRPDRQPEFTQLDIELSFTSR-D 703
            |:| ..|.||:|.|||||:||:||:.||..|:|:|||:|||..|.||||||||:|:|:||..: .
pombe   200 PSRLNPGKFYALPQSPQQYKQILMASGIGNYYQIARCFRDEDLRFDRQPEFTQIDLEMSFVDKPH 264

  Fly   704 DIMQLIEETL--RYSWPKDFPRLQTPFRRITYEEAMEKYGNDKPDTRFGFLLNNVSEIIEKSDEF 766
            :||:::|:.|  ..|:.|.. .|..||:.|||:.|::|||:||||.||...|.|::.::.|.|..
pombe   265 EIMEVVEDLLVRLVSFAKGI-TLAKPFQHITYQHAIDKYGSDKPDIRFELPLKNITSLLPKQDPL 328

  Fly   767 KEK----YDDLGAYAIVVRASEAFWNGAARKHYESLGKEFKGTLFVRKFGPTKDVQEKLGKLLG- 826
            ...    |:||         |.:..|..:||..|::|:....| .:|:....:...:||.:|..
pombe   329 ISTEILVYNDL---------SHSLSNAESRKLCEAVGENVVVT-SIREHSQLQTWVKKLPQLRQL 383

  Fly   827 EDVATEVADKFDLEENDLLFLGIGSK--VETRELLGRIRLDYQDFLVENAKIKKPND--FRFLWV 887
            ..||.|:..|..:..|.::|:....|  |.....||::||...:.||:...:.:.:.  .:|:||
pombe   384 PIVAEELNQKLQIGINSIVFMTNRPKYLVSGTTPLGKLRLLLHELLVKKKALPELDKDLLKFVWV 448

  Fly   888 IDFPLFERNRETNQ-LESVHHPFTLPHSDDLENFATSCENLE----SIRSQAYDLVLNGQEVGGG 947
            :|||||....|.|| :.|.|||||.||.||:       ..||    |:|...||:|:||.|:|||
pombe   449 VDFPLFSPTEEKNQSITSTHHPFTAPHWDDV-------HLLEKKPLSVRGLHYDIVVNGIELGGG 506

  Fly   948 SIRIHDRDMQHFILEQILKIPHDH---LSHLLSALESGCPPHGGIALGLDRLIAILCRARSIRDV 1009
            |||||:.|:|.|:|:.:||:|.:.   ..||:..|.||||||||||||.|||.|:|..|..||:|
pombe   507 SIRIHNPDIQRFVLKDVLKLPENRYATFEHLIRVLSSGCPPHGGIALGFDRLAALLTNAPGIREV 571

  Fly  1010 IAFPKSLNGRDPLSNAPVPISDEEMRLYHLSVVDEEE 1046
            |||||:.:|.|.|..:|..|.:|.::.|::::..:.:
pombe   572 IAFPKTSSGADLLIGSPSAIPEEMLKDYNVAITRQTQ 608

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AspRS-m	NP_001260520.2	Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with oligonucleotide/oligosaccharide (OB) fold.	148..303	CDD:471953
		EcAspRS_like_N	291..410	CDD:239812
		aspS	462..1045	CDD:234775	233/619 (38%)
dar2	NP_587777.1	AspS	14..604	CDD:439943	233/616 (38%)