Protein Alignment CG31689 and ABCG1

DIOPT Version :9

• Sequence 1: NP_001259954.1
• Gene: CG31689 / 326154
• FlyBaseID: FBgn0031449
• Length: 624
• Species: Drosophila melanogaster
• Sequence 2: XP_024307909.1
• Gene: ABCG1 / 9619
• HGNCID: 73
• Length: 786
• Species: Homo sapiens
• Alignment Length: 600
• Identity: 230/600 - (38%)
• Similarity: 351/600 - (58%)
• Gaps: 41/600 - (6%)

  Fly    42 KSVLKGIKGTFKSGELTAIMGPSGAGKSSLMNILTGLTKSGVSGKIEIGKA-------RKLCGYI 99
            |::||||.|.|.||||.|||||||||||:|||||.|..::|:.|.:.|...       ||:..||
Human   206 KTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVSCYI 270

  Fly   100 MQDDHFFPYFTVEETMLMAATLKISNQCVSLKEK----RTLIDYLLNSLKLTKTRQTKCSNLSGG 160
            ||||...|:.||:|.|:::|.||       |:||    |.::..:|.:|.|.....|:..:||||
Human   271 MQDDMLLPHLTVQEAMMVSAHLK-------LQEKDEGRREMVKEILTALGLLSCANTRTGSLSGG 328

  Fly   161 QKKRLSIALELIDNPAVLFLDEPTTGLDSSSSFDTIQLLRGLANEGRTIVCTIHQPSTNIYNLFN 225
            |:|||:|||||::||.|:|.||||:||||:|.|..:.|::|||..||:|:|||||||..::.||:
Human   329 QRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKGLAQGGRSIICTIHQPSAKLFELFD 393

  Fly   226 LVYVLSAGRCTYQGTPQNTVMFLSSVGLECPPYHNPADFLLECANGDYGDQTEALAEAAKDIRWR 290
            .:||||.|:|.|:|...|.|.:|..:||.||.|||||||::|.|:|:||||...|..|.::....
Human   394 QLYVLSQGQCVYRGKVCNLVPYLRDLGLNCPTYHNPADFVMEVASGEYGDQNSRLVRAVREGMCD 458

  Fly   291 YDQQLMQGEDADA-------PSETQVAKFNESQSPGQVQVQVQKIEIQNMESSKDLTKHTYPPTE 348
            .|.:...|.||:.       |||             :|: |.::::....:||.....|::..:.
Human   459 SDHKRDLGGDAEVNPFLWHRPSE-------------EVK-QTKRLKGLRKDSSSMEGCHSFSASC 509

  Fly   349 YMRLWLLIGRCHLQFFRDWTLTYLKLGIHVLCSILIGLFFGDSGSNATKQISNVGMIMIHCVYLW 413
            ..:..:|..|..|...||..||:|::..|:...:||||.:...|:.|.|.:||.|.:....::|.
Human   510 LTQFCILFKRTFLSIMRDSVLTHLRITSHIGIGLLIGLLYLGIGNEAKKVLSNSGFLFFSMLFLM 574

  Fly   414 YTTIMPGILRYPAEIEIIRKETFNNWYKLRTYYLATIITSTPVHIIFSTVYITIGYLMTDQPVEM 478
            :..:||.:|.:|.|:.:..:|..|.||.|:.||||..:...|..|:|...|.:|.|.||.||.:.
Human   575 FAALMPTVLTFPLEMGVFLREHLNYWYSLKAYYLAKTMADVPFQIMFPVAYCSIVYWMTSQPSDA 639

  Fly   479 DRFVKYLLSAVVVTICADGLGVFLGTVLNPVN-GTFVGAVSTSCMLMFSGFLILLNHIPAAMRFM 542
            .|||.:.....:.::.|..||:.:|.....:. .||||.|:...:|:||||.:..:.||..:::|
Human   640 VRFVLFAALGTMTSLVAQSLGLLIGAASTSLQVATFVGPVTAIPVLLFSGFFVSFDTIPTYLQWM 704

  Fly   543 AYISPLRYALENMVISLYGNQRGQLICPPTEFYCHFKNAVTVLRQFGMEDGDFGHNILMILIQIA 607
            :|||.:||..|.:::|:||..|..|.|...| .|||:.:..:||:..:|:.....:.:::.|...
Human   705 SYISYVRYGFEGVILSIYGLDREDLHCDIDE-TCHFQKSEAILRELDVENAKLYLDFIVLGIFFI 768

  Fly   608 IFKVLSYFTLKHKIK 622
            ..::::||.|::||:
Human   769 SLRLIAYFVLRYKIR 783

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31689	NP_001259954.1	3a01204	15..622	CDD:273361	229/598 (38%)
		ABCG_EPDR	26..239	CDD:213180	105/207 (51%)
		ABC2_membrane	355..558	CDD:279410	70/203 (34%)
ABCG1	XP_024307909.1	3a01204	202..786	CDD:273361	230/599 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165141401
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S2712
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D177791at33208
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48041
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	9	8.760