DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31689 and ABCG10

DIOPT Version :9

Sequence 1:	NP_001259954.1	Gene:	CG31689 / 326154	FlyBaseID:	FBgn0031449	Length:	624	Species:	Drosophila melanogaster
Sequence 2:	NP_175734.1	Gene:	ABCG10 / 841761	AraportID:	AT1G53270	Length:	590	Species:	Arabidopsis thaliana

Alignment Length:	601	Identity:	150/601 - (24%)
Similarity:	278/601 - (46%)	Gaps:	78/601 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 DREKKSVLKGIKGTFKSGELTAIMGPSGAGKSSLMNILTGLTKSG-VSGKIEIG-------KARK 94
            ::|:|.:||.:....:|.|:|||.|||||||::|:.||.|....| |||::.:.       :.|:
plant    44 EKEEKVILKDVSCDARSAEITAIAGPSGAGKTTLLEILAGKVSHGKVSGQVLVNGRPMDGPEYRR 108

  Fly    95 LCGYIMQDDHFFPYFTVEETMLMAA--TLKISNQCVSLKEKRTLIDYLLNSLKLTKTRQTKCSNL 157
            :.|::.|:|..||:.||:||:..:|  .||...:..:.|.||.:.:..|..:..::..|...|.:
plant   109 VSGFVPQEDALFPFLTVQETLTYSALLRLKTKRKDAAAKVKRLIQELGLEHVADSRIGQGSRSGI 173

  Fly   158 SGGQKKRLSIALELIDNPAVLFLDEPTTGLDSSSSFDTIQLLRGLA-NEGRTIVCTIHQPSTNIY 221
            |||:::|:||.:||:.:|.|:.:||||:||||:|:...:.||:.:. .:|:|||.|||||...|.
plant   174 SGGERRRVSIGVELVHDPNVILIDEPTSGLDSASALQVVTLLKDMTIKQGKTIVLTIHQPGFRIL 238

  Fly   222 NLFNLVYVLSAGRCTYQGTPQNTVMFLSSVGLECPPYHNPADFLLECANGDYGDQTEALAEAA-- 284
            ...:.:.:||.|.....|:..:....:...|.:.|...|..::.::.|......:|::..|.:
plant   239 EQIDRIVLLSNGMVVQNGSVYSLHQKIKFSGHQIPRRVNVLEYAIDIAGSLEPIRTQSCREISCY 303

  Fly   285 -KDIRWRYDQQLMQGEDADAPSETQVAKFNESQSPGQVQVQVQKIEIQNMESSKDL--TKHTYPP 346
             ....|:.......||              ..||.......:::::|....|.|::  ||..:
plant   304 GHSKTWKSCYISAGGE--------------LHQSDSHSNSVLEEVQILGQRSCKNIFRTKQLF-- 352

  Fly   347 TEYMRLWLLIGRCHLQFFRDWTLTYLKLGIHVLCSILIGLFFGDSGSNATK-QISNVGMIMIHCV 410
                                 |...|:..|   ..:::|..:.:.|:...: ::...|.......
plant   353 ---------------------TTRALQASI---AGLILGSIYLNVGNQKKEAKVLRTGFFAFILT 393

  Fly   411 YLWYTTIMPGILRYPAEIEIIRKETFNNWYKLRTYYLATIITSTPVHIIFSTVYITIGYLMTDQP 475
            :|..:| ..|:..:..:..|:.:||....|::.:|.||..:...|..:|.|.::.|..|.:....
plant   394 FLLSST-TEGLPIFLQDRRILMRETSRRAYRVLSYVLADTLIFIPFLLIISMLFATPVYWLVGLR 457

  Fly   476 VEMDRFVKYLLSAVVVTICADG-LGVFLGTVLNPVNGTFVGAVSTSCMLMFSGFLILLNHIPAAM 539
            .|:|.|:.:.|...:|.:.::. :..|...|.|.:.||.|.:.......:|||:.|..:.||...
plant   458 RELDGFLYFSLVIWIVLLMSNSFVACFSALVPNFIMGTSVISGLMGSFFLFSGYFIAKDRIPVYW 522

  Fly   540 RFMAYISPLRYALENMVISLYGNQRGQLICPPTEFYCHFKNAVTVLRQFGMEDGDFGHNILMILI 604
            .||.|:|..:|..|.::|:.|   ||.:.                |:|..:::.....|:.::..
plant   523 EFMHYLSLFKYPFECLMINEY---RGDVF----------------LKQQDLKESQKWSNLGIMAS 568

  Fly   605 QIAIFKVLSYFTLKHK 620
            .|..::||.:|.|.::
plant   569 FIVGYRVLGFFILWYR 584

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31689	NP_001259954.1	3a01204	15..622	CDD:273361	150/601 (25%)
		ABCG_EPDR	26..239	CDD:213180	77/211 (36%)
		ABC2_membrane	355..558	CDD:279410	44/204 (22%)
ABCG10	NP_175734.1	3a01204	27..589	CDD:273361	150/601 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	121	1.000	Domainoid score	I1855
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48041
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.910