DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31689 and ABCG35

DIOPT Version :9

Sequence 1:	NP_001259954.1	Gene:	CG31689 / 326154	FlyBaseID:	FBgn0031449	Length:	624	Species:	Drosophila melanogaster
Sequence 2:	NP_172973.1	Gene:	ABCG35 / 838087	AraportID:	AT1G15210	Length:	1442	Species:	Arabidopsis thaliana

Alignment Length:	651	Identity:	160/651 - (24%)
Similarity:	285/651 - (43%)	Gaps:	122/651 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 SPFNIIFEDLYYRV-------EVGKDREKKSVLKGIKGTFKSGELTAIMGPSGAGKSSLMNILTG 77
            :|..:.|:|:.|.|       |.|....:..:|||:...|:.|.|||:||.|||||::||::|.|
plant   836 TPLAMSFDDVKYFVDMPAEMREQGVQETRLQLLKGVTSAFRPGVLTALMGVSGAGKTTLMDVLAG 900

  Fly    78 LTKSG-VSGKIEI-GKARK------LCGYIMQDDHFFPYFTVEETMLMAATLKISNQCVSLKEKR 134
            ....| :.|.:.: |..:|      :.||..|.|...|..||.|:::.:|.|:::.: ||.::|.
plant   901 RKTGGYIEGDVRVSGFPKKQETFARISGYCEQTDIHSPQVTVRESLIFSAFLRLAKE-VSKEDKL 964

  Fly   135 TLIDYLLNSLKLTKTRQT-----KCSNLSGGQKKRLSIALELIDNPAVLFLDEPTTGLDSSSSFD 194
            ..:|.::..::|...|..     ..:.||..|:|||:||:||:.||:::|:||||:|||:.::..
plant   965 MFVDQVMELVELVDLRDAIVGLPGVTGLSTEQRKRLTIAVELVANPSIIFMDEPTSGLDARAAAI 1029

  Fly   195 TIQLLRGLANEGRTIVCTIHQPSTNIYNLFN-LVYVLSAGRCTYQG----TPQNTVMFLSSV-GL 253
            .::.:|...:.|||:||||||||.:|:..|: |:.:...|...|.|    .....|.:..|. |:
plant  1030 VMRAVRNTVDTGRTVVCTIHQPSIDIFEAFDELLLMKRGGHVIYSGPLGRNSHKVVEYFESFPGV 1094

  Fly   254 -ECPPYHNPADFLLECANGDYGDQTEALAEAAKDIRWRYDQQLMQGED-ADAPSETQVAKFNESQ 316
             :.|..:|||.::||.:         :||           .:|..|.| |:....:.:.:.|::
plant  1095 PKIPEKYNPATWMLEAS---------SLA-----------AELKLGVDFAELYKASALCQRNKA- 1138

  Fly   317 SPGQVQVQVQKIEIQNMESSKDLTKHTYPPTEY-MRLWLLIGRCHLQFFRDWTLTY--------L 372
                   .||::.:. .:.:.||    |..|:: ...|.....|   .::.| .||        :
plant  1139 -------LVQELSVP-PQGATDL----YFATQFSQNTWGQFKSC---LWKQW-WTYWRSPDYNLV 1187

  Fly   373 KLGIHVLCSILIGLFF---GDSGSNATKQISNVGMIMIHCVYLWY---TTIMPGILRYPAEIEII 431
            :....:..|::||..|   |...||.......:|.|....|::..   :|:.|.:   ..|..:.
plant  1188 RFIFTLATSLMIGSVFWQIGGKRSNVQDLTMVIGAIYAAVVFVGINNCSTVQPMV---AVERTVF 1249

  Fly   432 RKETFNNWYKLRTYYLATIITSTPVHIIFSTVYITIGYLMTDQPVEMDRFVKYL----------- 485
            .:|.....|....|.::.:....|..:|.:|.|..|.|.|.....:..:|:.::
plant  1250 YREKAAGMYSAIPYAISQVTCELPYVLIQTTYYSLIIYSMVGFEWKASKFLWFIFINYFSFLYWT 1314

  Fly   486 ---LSAVVVTICADGLGVFLGTVLNPVNGTFVGAVSTSCMLMFSGFLILLNHIPAAMRFMAYISP 547
               :..|.:|.......:|.        ..|.|..:     :||||.|....||....:..:|.|
plant  1315 YYGMMTVSLTPNQQVASIFA--------SAFYGIFN-----LFSGFFIPRPKIPKWWVWYYWICP 1366

  Fly   548 LRYALENMVISLYGNQRGQLI----CPPTEFYCHFKNAVTVLRQFGMEDGDFGHNILMILIQIAI 608
            :.:.:..::.|.||:....:.    .|......:.|:      |:|.| .|:...:..:|:...:
plant  1367 VAWTIYGLITSQYGDVETPIALLGGAPGLTVKQYIKD------QYGFE-SDYMGPVAGVLVGFTV 1424

  Fly   609 F 609
            |
plant  1425 F 1425

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31689	NP_001259954.1	3a01204	15..622	CDD:273361	160/651 (25%)
		ABCG_EPDR	26..239	CDD:213180	82/233 (35%)
		ABC2_membrane	355..558	CDD:279410	42/230 (18%)
ABCG35	NP_172973.1	PLN03140	8..1442	CDD:215599	160/651 (25%)
		ABC_trans_N	88..163	CDD:291196
		ABCG_PDR_domain1	182..424	CDD:213200
		ABC2_membrane	525..731	CDD:279410
		PDR_assoc	738..802	CDD:285559
		ABCG_PDR_domain2	837..1075	CDD:213199	83/238 (35%)
		ABC2_membrane	1170..1375	CDD:279410	42/224 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D324553at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.920