DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31689 and ABCG8

DIOPT Version :9

Sequence 1:	NP_001259954.1	Gene:	CG31689 / 326154	FlyBaseID:	FBgn0031449	Length:	624	Species:	Drosophila melanogaster
Sequence 2:	NP_200098.1	Gene:	ABCG8 / 835363	AraportID:	AT5G52860	Length:	589	Species:	Arabidopsis thaliana

Alignment Length:	611	Identity:	172/611 - (28%)
Similarity:	277/611 - (45%)	Gaps:	103/611 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 VLKGIKGTFKSGELTAIMGPSGAGKSSLMNILTGLTKSGVSGKIEIGKA-------RKLCGYIMQ 101
            :|:.|..|....|:.|::||||||||:|::||...| |..||.|.:...       ||:..|:.|
plant    44 ILRNITLTAHPTEILAVVGPSGAGKSTLLDILASKT-SPTSGSILLNSIPINPSSYRKISSYVPQ 107

  Fly   102 DDHFFPYFTVEETMLMAATLKISNQCVSLKEKRTLIDYLLNSLKLTKTRQTK-CSNLSGGQKKRL 165
            .|.|||..||.||...||.|.:.|..:..:    .:..||:.|.||....|: ...||||:::|:
plant   108 HDSFFPLLTVSETFSFAACLLLPNPSIVSE----TVTSLLSELNLTHLSHTRLAQGLSGGERRRV 168

  Fly   166 SIALELIDNPAVLFLDEPTTGLDSSSSFDTIQLLRGLA-NEGRTIVCTIHQPSTNIYNLFNLVYV 229
            ||.|.|:.:|..|.|||||:||||.|:||.|.:|:.:| :..||::.:|||||..|.::.:.:.:
plant   169 SIGLSLLHDPCFLLLDEPTSGLDSKSAFDVIHILKSIAVSRQRTVILSIHQPSFKILSIIDRLLL 233

  Fly   230 LSAGRCTYQGTPQNTVMFLSSVGLECPPYHNPADFLLECANGDYGDQTEALAEAAKDIRWRYDQQ 294
            ||.|...|.|...:...||...|...||..|..::.:|..                       |:
plant   234 LSKGTVVYHGRLDSLEGFLLFKGFTVPPQLNSLEYAMEIL-----------------------QE 275

  Fly   295 LMQGE---DADAPSETQVAKFNESQSPGQVQVQVQKIEIQNMESSKDLTKHTYPPTEY----MRL 352
            |.:.:   ||.|....:..|..|.||    .|:.:|..|                ||.    .|.
plant   276 LRESDGNTDATALPSIENRKQREKQS----IVRYRKSRI----------------TEISLLARRF 320

  Fly   353 WLLIGRCHLQFFRDWTLTYLKLGIHVLCSILIGLFFGDSGSNATKQISNVGMIMIHCVYLWYTT- 416
            |.:|.|.. |......|..|.:|: ||.:|.|.:..|.:|..     ...||......:|..:|
plant   321 WKIIYRTR-QLLLTNALEALVVGL-VLGTIYINIGIGKAGIE-----KRFGMFAFTLTFLLSSTT 378

  Fly   417 -IMPGILRYPAEIEIIRKETFNNWYKLRTYYLATIITSTP----VHIIFS-TVYITIGYLMTDQP 475
             .:|..:.   |..|:.:||.:..|:|.::.||..:...|    :.||:| :||..||...|.|
plant   379 ETLPIFIN---ERPILLRETSSGIYRLSSHILANTLVFLPYLFVISIIYSVSVYFLIGLCPTWQ- 439

  Fly   476 VEMDRFVKYLLSAVVVTICADGLGVFLGTVL-NPVNGTFVGAVSTSCMLMFSGFLILLNHIPAAM 539
                .|..::|...::.:.|:...:||.::. |.:.||.:..:..:...:|||:.|....:|...
plant   440 ----AFGYFVLVIWIILLMANSFVLFLSSLAPNYITGTSLVTILLAAFFLFSGYFISKESLPKYW 500

  Fly   540 RFMAYISPLRYALENMVISLYGNQRGQLICPPTEFYCHFKNAVT---------VLRQFGMEDGDF 595
            .||.:.|..:|||:.::|:.|.       |..::.....:.|.|         ||::.|:.:...
plant   501 LFMYFFSMYKYALDALLINEYS-------CLASKCLVWLEEAQTKICMVTGGDVLKKKGLHEKQR 558

  Fly   596 GHNILMILIQIAIFKVLSYFTLKHKI 621
            ..|:.::|....:::||.:..|..::
plant   559 WFNVYVLLGFFVLYRVLCFLALLRRV 584

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31689	NP_001259954.1	3a01204	15..622	CDD:273361	172/611 (28%)
		ABCG_EPDR	26..239	CDD:213180	81/203 (40%)
		ABC2_membrane	355..558	CDD:279410	54/210 (26%)
ABCG8	NP_200098.1	P-loop_NTPase	29..243	CDD:304359	81/203 (40%)
		3a01204	44..584	CDD:273361	172/609 (28%)
		ABC2_membrane	316..519	CDD:279410	56/217 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48041
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.910