DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31689 and ABCG43

DIOPT Version :9

Sequence 1:	NP_001259954.1	Gene:	CG31689 / 326154	FlyBaseID:	FBgn0031449	Length:	624	Species:	Drosophila melanogaster
Sequence 2:	NP_680694.3	Gene:	ABCG43 / 827189	AraportID:	AT4G15236	Length:	1390	Species:	Arabidopsis thaliana

Alignment Length:	632	Identity:	148/632 - (23%)
Similarity:	295/632 - (46%)	Gaps:	82/632 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 PFNIIFEDLYYRVEVGKDREKKSVLKGIKGTFKSGELTAIMGPSGAGKSSLMNILTG-LTKSGVS 84
            |....|:|:.|.:|..:.: |..:|..:.|.||.|.|||:||.|||||::|:::|:| .|:..:.
plant   795 PLTFTFQDVQYFIETPQGK-KLQLLSDVTGAFKPGVLTALMGVSGAGKTTLLDVLSGRKTRGDIK 858

  Fly    85 GKIEIG---KAR----KLCGYIMQDDHFFPYFTVEETMLMAATLKISNQC-VSLKEKRTLIDYLL 141
            |:||:|   |.:    ::.||..|.|...|..||:|::..:|.|::  .| :|.:.|..:::.:|
plant   859 GQIEVGGYVKVQDTFSRVSGYCEQFDIHSPNLTVQESLKYSAWLRL--PCNISSETKSAIVNEVL 921

  Fly   142 NSLKLTKTRQT-----KCSNLSGGQKKRLSIALELIDNPAVLFLDEPTTGLDSSSSFDTIQLLRG 201
            .:::|.:.:.:     ..|.::..|:|||:||:||:.||:::|:||||||||:.::...::.::.
plant   922 ETIELEEIKDSLVGVPGISGVTAEQRKRLTIAVELVSNPSIIFMDEPTTGLDARAAAIVMRAVKN 986

  Fly   202 LANEGRTIVCTIHQPSTNIYNLFN-LVYVLSAGRCTYQG-----TPQNTVMFLSSVGL-ECPPYH 259
            :|..|||:||||||||.:|:..|: |:.:.:.|:..|.|     :.:....|:|..|: :.....
plant   987 IAETGRTVVCTIHQPSIDIFEAFDELILMKNGGKIIYYGPLGQHSSKVIEYFMSIPGVPKLKENS 1051

  Fly   260 NPADFLLECANGDYGDQTEALAEAAKDIRWRYDQQLMQGEDADAPSETQVAKFNESQSPGQVQVQ 324
            |||.::|:..:....|      :...|:...|::..:               |.|:      ::.
plant  1052 NPATWILDITSKSSED------KLGVDLAHIYEESTL---------------FKEN------KMV 1089

  Fly   325 VQKIEIQNMESSKDLTKHTYPPTEYMRLWLLIGRCHLQFFRDWTLTYLKLGIHVLCSILIGLFFG 389
            :::....::.|.:.:....|..|.:.:....:.:.||.::|:.:....::.......:|.|:.|
plant  1090 IEQTRCTSLGSERLILSSRYAQTSWEQFKACLWKQHLSYWRNPSYNLTRIIFMCFTCMLCGILF- 1153

  Fly   390 DSGSNATKQISN-------VGMIMIHCVYLWYTTIMPGILRYPAEIEIIRKETFNNWYKLRTYYL 447
               ....|:|:|       .|.:....::.........|.....|..:..:|.|:..|....|.|
plant  1154 ---LQKAKEINNQQDLFNVFGSMFTVVLFSGINNCSTVIFCVATERNVFYRERFSRMYNPWAYSL 1215

  Fly   448 ATIITSTPVHIIFSTVYITIGYLMTDQPVEMDRFVKYLLSAVVVTICADGLGVFLGTVLNPVNGT 512
            |.::...|..:..|.:|:.|.|.|......:.:......|.....:..:..|:.|..|...|:..
plant  1216 AQVLVEIPYSLFQSIIYVIIVYPMVGYHWSVYKVFWSFYSIFCSLLIFNYFGMLLVVVTPNVHIA 1280

  Fly   513 FVGAVSTSCML-MFSGFLILLNHIPAAMRFMAYISPLRYALENMVISLYGNQRGQLICPPTEFYC 576
            |....|...:: :|:|:::...:||....:|.|:||..:.|..::.|.||:...:::.     :.
plant  1281 FTLRSSFYAIVNLFAGYVMPKPNIPRWWIWMYYLSPTSWVLNGLLTSQYGDMEKEILA-----FG 1340

  Fly   577 HFKNAVTVLRQFGMEDGDFGHN--------ILMILIQIAIFKVLSYF 615
            ..|.....|..:      ||:.        :::|...|.:..:.::|
plant  1341 EKKKVSAFLEDY------FGYRYDSLALVAVVLIAFPILLASLFAFF 1381

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31689	NP_001259954.1	3a01204	15..622	CDD:273361	148/632 (23%)
		ABCG_EPDR	26..239	CDD:213180	81/227 (36%)
		ABC2_membrane	355..558	CDD:279410	40/210 (19%)
ABCG43	NP_680694.3	AAA	13..1390	CDD:333001	148/632 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D324553at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.920