DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31689 and ABCG18

DIOPT Version :9

Sequence 1:	NP_001259954.1	Gene:	CG31689 / 326154	FlyBaseID:	FBgn0031449	Length:	624	Species:	Drosophila melanogaster
Sequence 2:	NP_191071.1	Gene:	ABCG18 / 824677	AraportID:	AT3G55110	Length:	708	Species:	Arabidopsis thaliana

Alignment Length:	576	Identity:	149/576 - (25%)
Similarity:	266/576 - (46%)	Gaps:	59/576 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 SSPFNIIFEDLYYRVEVGK----DREK----KSVLKGIKGTFKSGELTAIMGPSGAGKSSLMNIL 75
            |.||.:.|.:|.|.|.:.:    .|.|    |::|..|.|..:.||:.|::|.||||||:|::.|
plant    58 SVPFLLSFNNLSYNVVLRRRFDFSRRKTASVKTLLDDITGEARDGEILAVLGGSGAGKSTLIDAL 122

  Fly    76 TG-LTKSGVSGKIEIGKARKL--------CGYIMQDDHFFPYFTVEETMLMAATLKISNQCVSLK 131
            .| :.:..:.|.:.:...:.|        ..|:||||..||..||:||::.|:..::.......|
plant   123 AGRVAEDSLKGTVTLNGEKVLQSRLLKVISAYVMQDDLLFPMLTVKETLMFASEFRLPRSLPKSK 187

  Fly   132 EKRTLIDYLLNSLKLTKTRQTKCSN-----LSGGQKKRLSIALELIDNPAVLFLDEPTTGLDSSS 191
             |...::.|::.|.|.....|...:     :|||:::|:||.:::|.:|.:|||||||:||||::
plant   188 -KMERVETLIDQLGLRNAADTVIGDEGHRGVSGGERRRVSIGIDIIHDPILLFLDEPTSGLDSTN 251

  Fly   192 SFDTIQLLRGLANEGRTIVCTIHQPSTNIYNLFNLVYVLSAGRCTYQGTPQNTVMFLSSVGLECP 256
            :|..:|:|:.:|..|..::.:|||||..|..|.:.:.:||.|:..:.|:|.:...|.||.|...|
plant   252 AFMVVQVLKRIAQSGSVVIMSIHQPSARIIGLLDRLIILSHGKSVFNGSPVSLPSFFSSFGRPIP 316

  Fly   257 PYHNPADFLLECANGDYGDQTEALAEAAKDIRWRYDQQLMQGEDADAPSETQVA---KFNESQSP 318
            ...|..:|.|:...     :.|..:|..:|: ..::::..|.:.|.|.::::|:   ....|.|.
plant   317 EKENITEFALDVIR-----ELEGSSEGTRDL-VEFNEKWQQNQTARATTQSRVSLKEAIAASVSR 375

  Fly   319 GQVQVQVQKIEIQNMESSKDLTKHTYPPTEYMRLWLLIGRCHLQFFRDWTLTYLKLGIHVLCSIL 383
            |::   |......|..|.:.::.:..||  ....::|..|    :.::|..|...:|:.:...::
plant   376 GKL---VSGSSGANPISMETVSSYANPP--LAETFILAKR----YIKNWIRTPELIGMRIGTVMV 431

  Fly   384 IGLFFG---------DSGSNATKQISNVGM-IMIHCVYLWYTTIMPGILRYPAEIEIIRKETFNN 438
            .||...         ..|:.........|| .|.:|       ....|..:..|..|..:||.:|
plant   432 TGLLLATVYWRLDNTPRGAQERMGFFAFGMSTMFYC-------CADNIPVFIQERYIFLRETTHN 489

  Fly   439 WYKLRTYYLATIITSTPVHIIFSTVYITIGYLMTDQPVEMDRFVKYLLSAVVVTICADGLGVFL- 502
            .|:..:|.::..:.|.|..:..|..:....:........::.|..|.|...........:..|:
plant   490 AYRTSSYVISHALVSLPQLLALSIAFAATTFWTVGLSGGLESFFYYCLIIYAAFWSGSSIVTFIS 554

  Fly   503 GTVLNPVNGTFVGAVSTSCMLMFSGFLILLNHIPAAMRFMAYISPLRYALENMVIS 558
            |.:.|.:....|.....|..|:..||.|..:.||....:..|||.|:|..|.::|:
plant   555 GLIPNVMMSYMVTIAYLSYCLLLGGFYINRDRIPLYWIWFHYISLLKYPYEAVLIN 610

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31689	NP_001259954.1	3a01204	15..622	CDD:273361	149/576 (26%)
		ABCG_EPDR	26..239	CDD:213180	77/234 (33%)
		ABC2_membrane	355..558	CDD:279410	43/213 (20%)
ABCG18	NP_191071.1	3a01204	57..707	CDD:273361	149/576 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48041
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.910