DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31689 and ABCG37

DIOPT Version :9

Sequence 1:	NP_001259954.1	Gene:	CG31689 / 326154	FlyBaseID:	FBgn0031449	Length:	624	Species:	Drosophila melanogaster
Sequence 2:	NP_190916.1	Gene:	ABCG37 / 824516	AraportID:	AT3G53480	Length:	1450	Species:	Arabidopsis thaliana

Alignment Length:	678	Identity:	176/678 - (25%)
Similarity:	303/678 - (44%)	Gaps:	110/678 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 EKLTQEFALRTMPDFATSS---------------PFNIIFEDLYYRVEV-------GKDREKKSV 44
            ||.|::.::|..   .|.|               |..:.|:||.|.|::       |.|::|..:
plant   816 EKSTEDSSVRKK---TTDSPVKTEEEDKMVLPFKPLTVTFQDLNYFVDMPVEMRDQGYDQKKLQL 877

  Fly    45 LKGIKGTFKSGELTAIMGPSGAGKSSLMNILTGLTKSG-VSGKIEIGKARK-------LCGYIMQ 101
            |..|.|.|:.|.|||:||.|||||::|:::|.|...|| :.|.|.|....|       :.||..|
plant   878 LSDITGAFRPGILTALMGVSGAGKTTLLDVLAGRKTSGYIEGDIRISGFPKVQETFARVSGYCEQ 942

  Fly   102 DDHFFPYFTVEETMLMAATLKISNQCVSLKEKRTLIDYLLNSLKLTKTRQ-----TKCSNLSGGQ 161
            .|...|..||||:::.:|.|:::.: :....|...:..:|.:::|.:.:.     |..|.||..|
plant   943 TDIHSPNITVEESVIYSAWLRLAPE-IDATTKTKFVKQVLETIELDEIKDSLVGVTGVSGLSTEQ 1006

  Fly   162 KKRLSIALELIDNPAVLFLDEPTTGLDSSSSFDTIQLLRGLANEGRTIVCTIHQPSTNIYNLFN- 225
            :|||:||:||:.||:::|:||||||||:.::...::.::.:|:.||||||||||||.:|:..|:
plant  1007 RKRLTIAVELVANPSIIFMDEPTTGLDARAAAIVMRAVKNVADTGRTIVCTIHQPSIDIFEAFDE 1071

  Fly   226 LVYVLSAGRCTYQGT----PQNTVMFLSSVGLECPPY---HNPADFLLECANGDYGDQTEALAEA 283
            ||.:...||..|.|.    .::.:.:..||. |.|..   ||||.::|:            ::..
plant  1072 LVLLKRGGRMIYTGPLGQHSRHIIEYFESVP-EIPKIKDNHNPATWMLD------------VSSQ 1123

  Fly   284 AKDIRWRYDQQLMQGEDADAPSETQVAKFNESQSPGQVQVQVQKIEIQNMESSKDLTKHTYPPTE 348
            :.:|....|...:..:.|.....:::.|.......|...:|.               |.|:..:.
plant  1124 SVEIELGVDFAKIYHDSALYKRNSELVKQLSQPDSGSSDIQF---------------KRTFAQSW 1173

  Fly   349 YMRLWLLIGRCHLQFFRDWTLTYLKLGIHVLCSILI-GLFFGDSGSNATKQISN---VGMIMIHC 409
            :.:...::.:.:|.::|..:...::: :|.|.|.|| |..|...|.|...|.|.   .|.|....
plant  1174 WGQFKSILWKMNLSYWRSPSYNLMRM-MHTLVSSLIFGALFWKQGQNLDTQQSMFTVFGAIYGLV 1237

  Fly   410 VYLWYTTIMPGILRYPAEIEIIRKETFNNWYKLRTYYLATIITSTPVHIIFSTVYITIGYLMTDQ 474
            ::|........:..:..|..::.:|.|...|....|.|..::|..|...|.:..::.:.|.|...
plant  1238 LFLGINNCASALQYFETERNVMYRERFAGMYSATAYALGQVVTEIPYIFIQAAEFVIVTYPMIGF 1302

  Fly   475 PVEMDRFVKYLLSAVVVTICADGLGVFLGTVLNPVNGTFVGAVSTSCML----MFSGFLILLNHI 535
            .....:....|.|.....:..:.|.:||.::   .....|.|:..|...    :||||||....:
plant  1303 YPSAYKVFWSLYSMFCSLLTFNYLAMFLVSI---TPNFMVAAILQSLFYVGFNLFSGFLIPQTQV 1364

  Fly   536 PAAMRFMAYISPLRYALENMVISLYGNQRGQLICPPTEFYCHFKNAVTVLR----QFGMEDGDFG 596
            |....::.|::|..:.|...:.|.||:...::..        |..:.||.|    .||     |.
plant  1365 PGWWIWLYYLTPTSWTLNGFISSQYGDIHEEINV--------FGQSTTVARFLKDYFG-----FH 1416

  Fly   597 HNIL------MILIQIAIFKVLSYFTLK 618
            |::|      .|...||:..:.::|..|
plant  1417 HDLLAVTAVVQIAFPIALASMFAFFVGK 1444

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31689	NP_001259954.1	3a01204	15..622	CDD:273361	172/665 (26%)
		ABCG_EPDR	26..239	CDD:213180	89/233 (38%)
		ABC2_membrane	355..558	CDD:279410	45/210 (21%)
ABCG37	NP_190916.1	PLN03140	54..1450	CDD:215599	176/678 (26%)
		ABC_trans_N	89..167	CDD:291196
		ABCG_PDR_domain1	186..429	CDD:213200
		ABC2_membrane	530..735	CDD:279410
		PDR_assoc	742..804	CDD:285559
		ABCG_PDR_domain2	847..1085	CDD:213199	90/238 (38%)
		ABC2_membrane	1180..1387	CDD:279410	45/210 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D324553at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920