DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31689 and ABCG31

DIOPT Version :9

Sequence 1:	NP_001259954.1	Gene:	CG31689 / 326154	FlyBaseID:	FBgn0031449	Length:	624	Species:	Drosophila melanogaster
Sequence 2:	NP_180555.2	Gene:	ABCG31 / 817544	AraportID:	AT2G29940	Length:	1426	Species:	Arabidopsis thaliana

Alignment Length:	646	Identity:	161/646 - (24%)
Similarity:	291/646 - (45%)	Gaps:	95/646 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 PFNIIFEDLYYRVEVGKDREKKSV-------LKGIKGTFKSGELTAIMGPSGAGKSSLMNILTGL 78
            |..:.|.::.|.|::.|:...:.|       |..:.|.|..|.|||::|.|||||::||::|.|.
plant   823 PLTMTFHNVNYYVDMPKEMRSQGVPETRLQLLSNVSGVFSPGVLTALVGSSGAGKTTLMDVLAGR 887

  Fly    79 TKSG-VSGKIEIGKARK-------LCGYIMQDDHFFPYFTVEETMLMAATLKISNQCVSLKEKRT 135
            ...| ..|.|.|....|       :.||:.|:|...|..||||::..:|:|::..: ::.::|:.
plant   888 KTGGYTEGDIRISGHPKEQQTFARISGYVEQNDIHSPQVTVEESLWFSASLRLPKE-ITKEQKKE 951

  Fly   136 LIDYLLNSLKLTKTRQT-----KCSNLSGGQKKRLSIALELIDNPAVLFLDEPTTGLDSSSSFDT 195
            .::.::..::|...|..     ..:.||..|:|||:||:||:.||:::|:||||:|||:.::...
plant   952 FVEQVMRLVELDTLRYALVGLPGTTGLSTEQRKRLTIAVELVANPSIIFMDEPTSGLDARAAAIV 1016

  Fly   196 IQLLRGLANEGRTIVCTIHQPSTNIYNLFN-LVYVLSAGRCTYQGT----PQNTVMFLSSVGLEC 255
            ::.:|...:.|||:||||||||.:|:..|: |:.:...|:..|.|.    .|..|.:...:. ..
plant  1017 MRTVRNTVDTGRTVVCTIHQPSIDIFEAFDELLLMKRGGQVIYGGKLGTHSQVLVDYFQGIN-GV 1080

  Fly   256 PPY---HNPADFLLECANGDYGDQTEALAEAAKDIRWRYDQQLMQGEDADAPSETQVAKFNESQS 317
            ||.   :|||.::||..       |.||.|       :|:.     |.||.        :.:|..
plant  1081 PPISSGYNPATWMLEVT-------TPALEE-------KYNM-----EFADL--------YKKSDQ 1118

  Fly   318 PGQVQVQVQKIEIQNMESSKDLTKHTYPPTEYMRLWLLIGRCHLQFFRDWTLTYLKLGIHVLCSI 382
            ..:|:..::::.:....|........|...:..:..|.:.:.:|.::|......::|....:.:.
plant  1119 FREVEANIKQLSVPPEGSEPISFTSRYSQNQLSQFLLCLWKQNLVYWRSPEYNLVRLVFTTIAAF 1183

  Fly   383 LIGLFFGDSGSNATKQ---ISNVGMIMIHCVYLWY---TTIMPGILRYPAEIEIIRKETFNNWYK 441
            ::|..|.|.||..|..   |:.:|.:...|::|..   :::.|.:   ..|..:..:|.....|.
plant  1184 ILGTVFWDIGSKRTSSQDLITVMGALYSACLFLGVSNASSVQPIV---SIERTVFYREKAAGMYA 1245

  Fly   442 LRTYYLATIITSTPVHIIFSTV------YITIGYLMTDQPVEMDRFVKYLLSAVVVTICADGLGV 500
            ...|..|..:...| :|:..|:      |.|||:..|     ..:||.||:...:........|:
plant  1246 PIPYAAAQGLVEIP-YILTQTILYGVITYFTIGFERT-----FSKFVLYLVFMFLTFTYFTFYGM 1304

  Fly   501 F-LGTVLNPVNGTFVGAVSTSCMLMFSGFLILLNHIPAAMRFMAYISPLRYALENMVISLYGNQR 564
            . :|...|......:.:...|...:.||||:....||....:..||.|:.:.|:.:::|..|:..
plant  1305 MAVGLTPNQHLAAVISSAFYSLWNLLSGFLVQKPLIPVWWIWFYYICPVAWTLQGVILSQLGDVE 1369

  Fly   565 GQLICP-----PTEFYCHFKNAVTVLRQFGMEDGDFGHNILMILIQIAIFKVLSYFTLKHK 620
            ..:..|     ..||..::         ||.:....|.:..:::...|:|  .|.|.|..|
plant  1370 SMINEPLFHGTVKEFIEYY---------FGYKPNMIGVSAAVLVGFCALF--FSAFALSVK 1419

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31689	NP_001259954.1	3a01204	15..622	CDD:273361	161/646 (25%)
		ABCG_EPDR	26..239	CDD:213180	78/233 (33%)
		ABC2_membrane	355..558	CDD:279410	45/215 (21%)
ABCG31	NP_180555.2	PLN03140	17..1426	CDD:215599	161/646 (25%)
		ABC_trans_N	77..151	CDD:291196
		ABCG_PDR_domain1	155..416	CDD:213200
		ABC2_membrane	517..723	CDD:279410
		PDR_assoc	730..793	CDD:285559
		ABCG_PDR_domain2	823..1061	CDD:213199	79/238 (33%)
		ABC2_membrane	1156..1361	CDD:279410	45/213 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D324553at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.920