DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31689 and abca3b

DIOPT Version :9

Sequence 1:	NP_001259954.1	Gene:	CG31689 / 326154	FlyBaseID:	FBgn0031449	Length:	624	Species:	Drosophila melanogaster
Sequence 2:	XP_009297489.1	Gene:	abca3b / 564344	ZFINID:	ZDB-GENE-050517-2	Length:	1703	Species:	Danio rerio

Alignment Length:	550	Identity:	124/550 - (22%)
Similarity:	208/550 - (37%)	Gaps:	185/550 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 MPDFATSSPFNIIFEDLYYRVEVGKDRE-KKSVLKGIKGTF------------------------ 52
            :|.:..|||          ||...|::| ::...|..||.|
Zfish   486 LPSYWCSSP----------RVAFLKEKEDEEDAEKASKGEFMEEEPAGLVAGVKIKRLAKVFKVG 540

  Fly    53 -KS-------------GELTAIMGPSGAGKSSLMNILTGLTKSGVSGKI---------EIGKARK 94
             ||             |::|.::|.:||||::.:::||||.... ||:.         ::...|:
Zfish   541 NKSKEAVRDLTLNMFEGQITVLLGHNGAGKTTTLSMLTGLFPPS-SGRAYINGYDICQDMALIRR 604

  Fly    95 LCGYIMQDDHFFPYFTVEETMLMAATL------KISNQCVSLKEKRTLIDYLLNSLKLTKTRQTK 153
            ..|...|.|..|...||.|.:|....|      ||..:          :|.::..|.|...|..|
Zfish   605 SLGLCPQHDVLFDNLTVREHLLFYTQLKGYPREKIPGE----------VDRIIRILNLEDKRNAK 659

  Fly   154 CSNLSGGQKKRLSIALELIDNPAVLFLDEPTTGLDSSSSFDTIQLLRGLANEGRTIVCTIH-QPS 217
            |..||||.|::|||.:.||.:..|:.|||||:|:|.|:...|..||:| ...||||:.|.| ...
Zfish   660 CKTLSGGMKRKLSIGIALIGDSKVVMLDEPTSGMDPSARRATWDLLQG-EKRGRTILLTTHFMDE 723

  Fly   218 TNIYNLFNLVYVLSAGRCTYQGTPQNTVMFLSS---VGLECPPYH---------NPADF--LLEC 268
            .::  |.:.:.::::|.....|:|    :||.:   .|     ||         |.::.  |:..
Zfish   724 ADL--LGDRIAIMASGELQCCGSP----LFLKNKYGAG-----YHMVIVKDAFCNVSEITRLVHM 777

  Fly   269 ANGDYGDQTEALAEAA----KDIRWRYD---QQLMQGEDADAPSETQVAKFNES-QSPGQVQVQV 325
            ...|...::.|.||.:    |:...|::   .:|....|     |..:|.:..| .:..:|.::|
Zfish   778 YVPDATLESSAGAELSYILPKESTSRFELLFAELEMNRD-----ELGIASYGASVTTMEEVFLRV 837

  Fly   326 QKIEIQNMESSKDLTKHTYPPTEYMRLWLLIGRCHLQFFRDWTLTYLKLGIHVLCSILIGLF--- 387
            .|:    ::||.|:.....|..:|.         |.:...|||:..        .|.:.|:.
Zfish   838 GKL----VDSSLDIQAIQLPALQYQ---------HERRSHDWTMDD--------SSSISGMTDVT 881

  Fly   388 -FGDSGSNATKQISNV--------------GMIMIHCVYLWYTTIMPGILRYPAEIEIIRKETFN 437
             |.||.:..::..||:              .|.:...:|.|                       .
Zfish   882 DFTDSCTMISEDGSNIKLNTGARLYMQQFYAMFLKRALYSW-----------------------R 923

  Fly   438 NWYKLRTYYLATIITSTPVHIIFSTVYITI 467
            ||..:...:|        |.:||:.:.:.:
Zfish   924 NWKVMVAQFL--------VPLIFTVLALVV 945

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31689	NP_001259954.1	3a01204	15..622	CDD:273361	123/547 (22%)
		ABCG_EPDR	26..239	CDD:213180	72/267 (27%)
		ABC2_membrane	355..558	CDD:279410	20/130 (15%)
abca3b	XP_009297489.1	AAA	1..>95	CDD:333001
abca3b	XP_009297489.1	AAA	<122..1695	CDD:333001	124/549 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000