Protein Alignment CG31689 and Abcg2

DIOPT Version :9

• Sequence 1: NP_001259954.1
• Gene: CG31689 / 326154
• FlyBaseID: FBgn0031449
• Length: 624
• Species: Drosophila melanogaster
• Sequence 2: NP_852046.1
• Gene: Abcg2 / 312382
• RGDID: 631345
• Length: 657
• Species: Rattus norvegicus
• Alignment Length: 641
• Identity: 173/641 - (26%)
• Similarity: 306/641 - (47%)
• Gaps: 78/641 - (12%)

  Fly    26 FEDLYYRVEVG-----KDREKKSVLKGIKGTFKSGELTAIMGPSGAGKSSLMNILTG-LTKSGVS 84
            |..:.|||:|.     :...:|.:|..|.|..|.| |.||:||:|.|||||:::|.. ....|:|
  Rat    39 FHHITYRVKVKSGFLVRKTAEKEILSDINGIMKPG-LNAILGPTGGGKSSLLDVLAARKDPRGLS 102

  Fly    85 GKIEIGKARK----LC--GYIMQDDHFFPYFTVEETMLMAATLKISNQCVSLKEKRTLIDYLLNS 143
            |.:.|..|.:    .|  ||::|||......||.|.:..:|.|::. :.:...||...|:.::..
  Rat   103 GDVLINGAPQPANFKCSSGYVVQDDVVMGTLTVRENLQFSAALRLP-KAMKTHEKNERINTIIKE 166

  Fly   144 LKLTKTRQTKCS-----NLSGGQKKRLSIALELIDNPAVLFLDEPTTGLDSSSSFDTIQLLRGLA 203
            |.|.|...:|..     .:|||::||.||.:|||.:|::|||||||||||||::...:.||:.::
  Rat   167 LGLDKVADSKVGTQFTRGISGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMS 231

  Fly   204 NEGRTIVCTIHQPSTNIYNLFNLVYVLSAGRCTYQGTPQNTVMFLSSVGLECPPYHNPADFLLEC 268
            .:||||:.:||||..:|:.||:.:.:|::|:..:.|..|..:.:.:|.|..|.||:|||||.|:.
  Rat   232 KQGRTIIFSIHQPRYSIFKLFDSLTLLASGKLMFHGPAQKALEYFASAGYHCEPYNNPADFFLDV 296

  Fly   269 ANGDYGDQTEALAEAAKDIRWRYDQQLMQGED---ADAPSETQVAKFN-ESQSPGQVQVQVQKIE 329
            .|||        :.|....|...|.:..:.|:   .:.|....:|:|. .|...|:.:.::.::.
  Rat   297 INGD--------SSAVMLNRGEQDHEANKTEEPSKREKPIIENLAEFYINSTIYGETKAELDQLP 353

  Fly   330 I-QNMESSKDLTKHTYPPTEYMRLWLLIGRCHLQFFRDWTLTYLKLGIHVLCSILIG-LFFGDSG 392
            : |..:.|....:..|..:...:|..:..|.......:...:..:|.:.|:..::|| |:|| ..
  Rat   354 VAQKKKGSSAFREPVYVTSFCHQLRWIARRSFKNLLGNPQASVAQLIVTVILGLIIGALYFG-LK 417

  Fly   393 SNATKQISNVGMIMIHCVYLWYTTIMPGILRYPAEIEIIRKETF-----NNWYKLRTYYLATIIT 452
            ::.|...:..|:.........:|::.      ..|:.::.|:.|     :.:|::.:|:...:::
  Rat   418 NDPTGMQNRAGVFFFLTTNQCFTSVS------AVELFVVEKKLFIHEYISGYYRVSSYFFGKLVS 476

  Fly   453 S-TPVHIIFSTVYITIGYLMTDQPVEMDRF---------VKYLLSAVVVTICADGLGVFLGTVLN 507
            . .|:..:.|.:|..:.|.|......::.|         |.|..|::.:.|.|....|.:.|:|.
  Rat   477 DLLPMRFLPSVIYTCLLYFMLGLKRTVEAFFIMMFTLIMVAYTASSMALAIAAGQSVVSVATLLM 541

  Fly   508 PVNGTFVGAVSTSCMLMFSGFLILLNHIPAAMRFMAYISPLRYALENMVISLYGNQ-RGQLICPP 571
            .::..|        |::|||.|:.|..|...:.::.|.|..||..    .:|..|: .||..||.
  Rat   542 TISFVF--------MMLFSGLLVNLRTIGPWLSWLQYFSIPRYGF----TALQHNEFLGQEFCPG 594

  Fly   572 TEFYCHFK--NAVTV------LRQFGMEDGDFG--HNILMILIQIAIFKVLSYFTL 617
            .....:..  |:.|:      |...|::...:|  .|.:.:...|.||..::|..|
  Rat   595 LNVTMNSTCVNSYTICTGNDYLINQGIDLSPWGLWRNHVALACMIIIFLTIAYLKL 650

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31689	NP_001259954.1	3a01204	15..622	CDD:273361	173/641 (27%)
		ABCG_EPDR	26..239	CDD:213180	85/229 (37%)
		ABC2_membrane	355..558	CDD:279410	42/218 (19%)
Abcg2	NP_852046.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..25
		3a01204	46..651	CDD:273361	170/634 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335078
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.740