Protein Alignment CG31689 and Abcg2

DIOPT Version :9

• Sequence 1: NP_001259954.1
• Gene: CG31689 / 326154
• FlyBaseID: FBgn0031449
• Length: 624
• Species: Drosophila melanogaster
• Sequence 2: NP_001342406.1
• Gene: Abcg2 / 26357
• MGIID: 1347061
• Length: 657
• Species: Mus musculus
• Alignment Length: 653
• Identity: 171/653 - (26%)
• Similarity: 309/653 - (47%)
• Gaps: 73/653 - (11%)

  Fly     9 ALRTMPDFATSSPFNIIFEDLYYRVEVG-----KDREKKSVLKGIKGTFKSGELTAIMGPSGAGK 68
            |:||:.:....|     |..:.|||:|.     :...:|.:|..|.|..|.| |.||:||:|.||
Mouse    27 AVRTLAEGDVLS-----FHHITYRVKVKSGFLVRKTVEKEILSDINGIMKPG-LNAILGPTGGGK 85

  Fly    69 SSLMNILTG-LTKSGVSGKIEIGKAR-----KLC-GYIMQDDHFFPYFTVEETMLMAATLKISNQ 126
            |||:::|.. ....|:||.:.|..|.     |.| ||::|||......||.|.:..:|.|::.
Mouse    86 SSLLDVLAARKDPKGLSGDVLINGAPQPAHFKCCSGYVVQDDVVMGTLTVRENLQFSAALRLP-- 148

  Fly   127 CVSLK--EKRTLIDYLLNSLKLTKTRQTKCS-----NLSGGQKKRLSIALELIDNPAVLFLDEPT 184
             .::|  ||...|:.::..|.|.|...:|..     .:|||::||.||.:|||.:|::|||||||
Mouse   149 -TTMKNHEKNERINTIIKELGLEKVADSKVGTQFIRGISGGERKRTSIGMELITDPSILFLDEPT 212

  Fly   185 TGLDSSSSFDTIQLLRGLANEGRTIVCTIHQPSTNIYNLFNLVYVLSAGRCTYQGTPQNTVMFLS 249
            ||||||::...:.||:.::.:||||:.:||||..:|:.||:.:.:|::|:..:.|..|..:.:.:
Mouse   213 TGLDSSTANAVLLLLKRMSKQGRTIIFSIHQPRYSIFKLFDSLTLLASGKLVFHGPAQKALEYFA 277

  Fly   250 SVGLECPPYHNPADFLLECANGDYGDQTEALAEAAKDIRWRYDQQLMQGEDADAPSETQVAKFNE 314
            |.|..|.||:|||||.|:..|||        :.|....|...|.:..:.|:.....:..:...:|
Mouse   278 SAGYHCEPYNNPADFFLDVINGD--------SSAVMLNREEQDNEANKTEEPSKGEKPVIENLSE 334

  Fly   315 ----SQSPGQVQVQVQKIE-IQNMESSKDLTKHTYPPTEYMRLWLLIGRCHLQFFRDWTLTYLKL 374
                |...|:.:.::.::. .|..:.:....:..|..:...:|..:..|.......:...:..:|
Mouse   335 FYINSAIYGETKAELDQLPGAQEKKGTSAFKEPVYVTSFCHQLRWIARRSFKNLLGNPQASVAQL 399

  Fly   375 GIHVLCSILIGLFFGDSGSNATKQISNVGMIMIHCVYLWYTTIMPGILRYPAEIEIIRKETF--- 436
            .:.|:..::||..:.|...:|....:..|::........::::.      ..|:.::.|:.|
Mouse   400 IVTVILGLIIGAIYFDLKYDAAGMQNRAGVLFFLTTNQCFSSVS------AVELFVVEKKLFIHE 458

  Fly   437 --NNWYKLRTYYLATIITS-TPVHIIFSTVYITIGYLMTDQPVEMDRFVKYLLSAVVVTICADGL 498
              :.:|::.:|:...:::. .|:..:.|.::..|.|.|......:|.|...:.:.::|...|..:
Mouse   459 YISGYYRVSSYFFGKVMSDLLPMRFLPSVIFTCILYFMLGLKKTVDAFFIMMFTLIMVAYTASSM 523

  Fly   499 GVFLGTVLNPVN-GTFVGAVSTSCMLMFSGFLILLNHIPAAMRFMAYISPLRY---ALENMVISL 559
            .:.:.|..:.|: .|.:..::...|::|||.|:.|..|...:.::.|.|..||   ||:
Mouse   524 ALAIATGQSVVSVATLLMTIAFVFMMLFSGLLVNLRTIGPWLSWLQYFSIPRYGFTALQ------ 582

  Fly   560 YGNQRGQLICP----PTEFYCHFKNAVTVLRQF----GMEDGDFG--HNILMILIQIAIFKVLSY 614
            |....||..||    .....|....|:....::    |:|...:|  .|.:.:...|.||..::|
Mouse   583 YNEFLGQEFCPGFNVTDNSTCVNSYAICTGNEYLINQGIELSPWGLWKNHVALACMIIIFLTIAY 647

  Fly   615 FTL 617
            ..|
Mouse   648 LKL 650

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31689	NP_001259954.1	3a01204	15..622	CDD:273361	168/647 (26%)
		ABCG_EPDR	26..239	CDD:213180	87/231 (38%)
		ABC2_membrane	355..558	CDD:279410	38/212 (18%)
Abcg2	NP_001342406.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..24
		3a01204	46..651	CDD:273361	164/629 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167831342
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.740