Protein Alignment CG31689 and wht-6

DIOPT Version :10

• Sequence 1: NP_001259954.1
• Gene: CG31689 / 326154
• FlyBaseID: FBgn0031449
• Length: 624
• Species: Drosophila melanogaster
• Sequence 2: NP_498425.2
• Gene: wht-6 / 188911
• WormBaseID: WBGene00007060
• Length: 613
• Species: Caenorhabditis elegans
• Alignment Length: 672
• Identity: 192/672 - (28%)
• Similarity: 324/672 - (48%)
• Gaps: 120/672 - (17%)

  Fly     2 EKLTQEFALRTM-PDFATSSPFNIIFEDLYY-RVEVGKDREKKSVLKGIKGTFKSGELTAIMGPS 64
            ||:.::.....: |.::|..  :|:...|:: .:.|...:||:.:||.:.|..|||||.|:||.|
 Worm     8 EKILEDVECTAVSPGYSTLG--DIVPVSLHWNNITVTTIKEKRLLLKNVSGYAKSGELLALMGAS 70

  Fly    65 GAGKSSLMNI-----LTGLTKSG---VSGKIEIGKARKLCGYIMQDDHFFPYFTVEETMLMAATL 121
            ||||::|:|:     |.||:..|   |:|.....|...:.|:..|::.|....||:|.:::.|.|
 Worm    71 GAGKTTLLNMLMCRNLKGLSTEGTITVNGNEMAHKISSISGFAQQEELFVGTLTVKEYLMIQAKL 135

  Fly   122 KISNQCVSLKEKRTLIDYLLNSLKLTKTRQTKC------SNLSGGQKKRLSIALELIDNPAVLFL 180
            :| |....|:|.|  :..:|:.|||.|.|.:|.      ..:|||:.:||:.|.|::.||::||.
 Worm   136 RI-NGSKKLREDR--VTDVLHQLKLWKCRDSKIGVIGEKKGISGGEARRLTFACEMLSNPSLLFA 197

  Fly   181 DEPTTGLDSSSSFDTIQLLRGLANEGRTIVCTIHQPSTNIYNLFNLVYVLSAGRCTYQGTPQNTV 245
            |||||||||..:...||:|:|:|..||||:|||||||:.:|.:|:.|..|:.|...:|||||.::
 Worm   198 DEPTTGLDSFMAESVIQILKGIAKTGRTIICTIHQPSSQLYQMFHRVIYLANGSTAFQGTPQESI 262

  Fly   246 MFLSSVGLECPPYHNPADFLLECANGDYGDQTEALAEAAKDIRWRYDQQLMQGEDADAPSETQVA 310
            .|....|...|..:||:::::                        |...:..|:
 Worm   263 SFFEKCGHRVPDEYNPSEWII------------------------YKLAVQPGQ----------- 292

  Fly   311 KFNESQSPGQVQVQVQKIEIQN-----MESSKDLTKHTYPP-----TEYMRLWLLIGRCHLQFFR 365
               |.||..::|..|::.|..:     ||...|:::...||     ..:.:::.|..||.:..:|
 Worm   293 ---EKQSNDRIQKIVEQYEDSDHQKRVMEQLSDVSEKIPPPEMHRANVFTQIFALSTRCGIDVWR 354

  Fly   366 DWTLTYLKLGIHVLCSILIGLFFGDSGSNATKQISNV--GMIMIHCVYLWYTTIMPGILRYPAEI 428
            ...||..|:...:|..:.|||.:..:..:| :.|.|:  .:..:...|: |:|....:.....|.
 Worm   355 APQLTLAKVIQKILFGLFIGLLYLRTPYDA-RGIHNINGALFFLAGEYI-YSTAYAIMFFLNNEF 417

  Fly   429 EIIRKETFNNWYKLRTYYLATIITSTPVHIIFST--------VYITIGYLMTDQPVEMDRFVKYL 485
            .::.:|..:..|.|.|||.|..|:..|   :|||        ||..||         ::..|..:
 Worm   418 PLVAREYHDGLYNLWTYYFARCISLIP---LFSTDGLILLFIVYWLIG---------LNTSVMQV 470

  Fly   486 LSAVVVTICADGLGVFLGTVLNPVNGTFVGAVSTSCML--------MFSGFLILLNHIPAAMRFM 542
            :.|.::|:.|.......|..::.:   |..|..|:.|.        :|.|.....|..|||:|::
 Worm   471 IVASIITVLASQAASAFGIAMSCI---FPTAQMTAVMASPPLVLFRLFGGLYGNTNTFPAAIRWL 532

  Fly   543 AYISPLRYALENMVISLYGNQRGQLICPPTEFYCHFKNAVT------VLRQFGMEDGDFGHNIL- 600
            .:||..|:|.|.:|:    ||..::    .:|:.:.||..|      ||..|...:.....:|:
 Worm   533 QWISMYRFAFEGLVV----NQWSEI----DDFHSNAKNNWTNSTTNDVLDYFAFSESAIPLDIIG 589

  Fly   601 MILIQIAIFKVLSYFTLKHKIK 622
            :|||.:| |.::.:..|.|::|
 Worm   590 LILISLA-FYLIGFIALVHRMK 610

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31689	NP_001259954.1	3a01204	15..622	CDD:273361	188/656 (29%)
wht-6	NP_498425.2	YlqF_related_GTPase	<3..>81	CDD:483945	27/74 (36%)
		3a01204	50..613	CDD:273361	183/628 (29%)