DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31689 and abcx-1

DIOPT Version :9

Sequence 1:	NP_001259954.1	Gene:	CG31689 / 326154	FlyBaseID:	FBgn0031449	Length:	624	Species:	Drosophila melanogaster
Sequence 2:	NP_495321.3	Gene:	abcx-1 / 183860	WormBaseID:	WBGene00006522	Length:	710	Species:	Caenorhabditis elegans

Alignment Length:	678	Identity:	138/678 - (20%)
Similarity:	247/678 - (36%)	Gaps:	164/678 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 TSSPF-NIIFEDLYYRVEVGKDREK--------KSVLKGIKGTFKSGELTAIMGPSGAGKSSLMN 73
            ::.|: |::...|.:..::....:|        |..:..|.....|.::.|||....:...||:.
Worm    64 STRPYPNLLLNKLSFSKDLRSSSDKVLLRLPVLKQEVHNISFELSSSDVLAIMYTKESETISLLK 128

  Fly    74 ILTGLTKSGVSGKIEIGKARKLCGYIMQDDHFFPYFTVEETM----LMAATLKIS---------N 125
            |:.|:  ..|.|        ||.|.|:.:.|......:|:|:    |.:.|..:|         |
Worm   129 IICGI--KDVRG--------KLSGDILVNGHRMSRDRLEKTIGFVSLESPTSTLSVRQYLHVHGN 183

  Fly   126 QCVSLKEK----RTLIDYLLNSLKLTKTRQTKCSNLSGGQKKRLSIALELIDNPAVLFLDEPTTG 186
            ....:.|:    ..||:.|:..|.|.......||.|:..|.:|:.:|.:|:.:|.:|...:....
Worm   184 FYPPMTERYGGVGHLINKLMTDLGLFPVSDIICSRLNRSQWQRVKVASQLVRDPTILVCSDIFKD 248

  Fly   187 LDSSSSFDTIQLLRGLA-NEGRTIVCTIHQPSTNIYNLFNLVYVLSAGRCTYQGTPQNTVMFLSS 250
            :|.......|..||..| ...|.::..|...|..|.|:|:...:|::||..|.|.|::...:..:
Worm   249 IDVHDQCFLIDYLREWAVKTNRIVIMAISPTSLQILNMFSKAMILASGRMIYFGPPKSMQQYFET 313

  Fly   251 VGLECPPYHNPADFLLECANGDYGDQTEALAEAAKDIRWRYDQQLMQGEDADAPSETQVA----K 311
            :|..||||.|..|:.::....|  :.|                     .||...|..::|    |
Worm   314 IGCPCPPYKNVCDYYVDLVTHD--NLT---------------------SDASRESSVRIARLVNK 355

  Fly   312 FNESQSPGQVQVQVQKIEIQNMESSK---DLTKHTYPPTE--YMRLWLLIGRCHLQFFRD-WTLT 370
            :|::..|           ::...|.|   ||      ||.  :|.|..||......|..: .:..
Worm   356 WNQTAPP-----------VRRTASGKFLLDL------PTAGIFMNLLTLISLFWFNFINNRASRI 403

  Fly   371 YLKLGIHVLCSIL------IGLFFGDSGSNATKQIS--------NVGMIMI-HCVYL-----WYT 415
            :..|.|..|.:.|      :.|...|:..|....:.        .:|::.: .|.:|     :|.
Worm   404 FFLLFIFSLSTCLSLHLSDLSLTLPDAFLNRNSYLELLIFYVPLFIGLVNLKKCTFLSEFDKFYL 468

  Fly   416 TIMPGILRYPAEIEIIRKETFNNWYKLRTYYLATIITSTPVHIIFSTVYITIGYLMTDQPVEMDR 480
            .|.   .|:..: |:::.....|.....:..:.:.:...|..:|.|.|:.....:.||...:...
Worm   469 FIS---ARHHLK-ELLKLSPLKNMCSSLSIIIVSFVVELPFLLITSMVFAMPMSIFTDFHQKSSN 529

  Fly   481 FVKYLL---SAVVVTICADGLGVFLGTVLNPVNGT-------FVGAVSTSCMLMFSGFLILLNHI 535
            .:..|:   |:..:.:....|      |:|.|:..       |...:|...:....||...::.|
Worm   530 HLTSLVSISSSFFINLSVTQL------VVNSVSNLSSEPLSFFFFVISWFSLFFACGFPFPIHSI 588

  Fly   536 PAAMRFMAYISPL--------RYALENMVISLYGNQRGQLICPPTEFYC--HFKNAVTVLR---Q 587
                  :.|.:||        |:..|:.. |||......|..|...:.|  .|.|...|.|   |
Worm   589 ------LKYFNPLFFPTTSVFRFLYEDSP-SLYPQLSVNLSTPIQLYSCGRTFLNTTQVTRGPCQ 646

  Fly   588 FGMEDGDFGHNILMILIQIAIFKVLSYF 615
                             :::.|::|||:
Worm   647 -----------------KVSSFELLSYY 657

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31689	NP_001259954.1	3a01204	15..622	CDD:273361	138/678 (20%)
		ABCG_EPDR	26..239	CDD:213180	55/238 (23%)
		ABC2_membrane	355..558	CDD:279410	40/241 (17%)
abcx-1	NP_495321.3	P-loop_NTPase	102..302	CDD:304359	52/209 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810