Protein Alignment CG31689 and Abcg1

DIOPT Version :9

• Sequence 1: NP_001259954.1
• Gene: CG31689 / 326154
• FlyBaseID: FBgn0031449
• Length: 624
• Species: Drosophila melanogaster
• Sequence 2: NP_033723.1
• Gene: Abcg1 / 11307
• MGIID: 107704
• Length: 666
• Species: Mus musculus
• Alignment Length: 622
• Identity: 239/622 - (38%)
• Similarity: 355/622 - (57%)
• Gaps: 56/622 - (9%)

  Fly    23 NIIFEDLYYRVEVG---KDREKKSVLKGIKGTFKSGELTAIMGPSGAGKSSLMNILTGLTKSGVS 84
            ||.|:||.|.|..|   |.:..|::||||.|.|.||||.|||||||||||:|||||.|..::|:.
Mouse    76 NIEFKDLSYSVPEGPWWKKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMK 140

  Fly    85 GKIEIGKA-------RKLCGYIMQDDHFFPYFTVEETMLMAATLKISNQCVSLKEK----RTLID 138
            |.:.|...       ||:..||||||...|:.||:|.|:::|.||       |:||    |.::.
Mouse   141 GAVLINGMPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLK-------LQEKDEGRREMVK 198

  Fly   139 YLLNSLKLTKTRQTKCSNLSGGQKKRLSIALELIDNPAVLFLDEPTTGLDSSSSFDTIQLLRGLA 203
            .:|.:|.|.....|:..:|||||:|||:|||||::||.|:|.||||:||||:|.|..:.|::|||
Mouse   199 EILTALGLLPCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKGLA 263

  Fly   204 NEGRTIVCTIHQPSTNIYNLFNLVYVLSAGRCTYQGTPQNTVMFLSSVGLECPPYHNPADFLLEC 268
            ..||:|||||||||..::.||:.:||||.|:|.|:|...|.|.:|..:||.||.|||||||::|.
Mouse   264 QGGRSIVCTIHQPSAKLFELFDQLYVLSQGQCVYRGKVSNLVPYLRDLGLNCPTYHNPADFVMEV 328

  Fly   269 ANGDYGDQTEALAEAAKDIRWRYDQQLMQGEDADA-------PSETQVAKFNESQSPGQVQVQVQ 326
            |:|:||||...|..|.::.....|.:...|.|.|.       |:|...|
Mouse   329 ASGEYGDQNSRLVRAVREGMCDADYKRDLGGDTDVNPFLWHRPAEEDSA---------------- 377

  Fly   327 KIEIQNMESSKDLTKHTYPPTEYMRLWLLIGRCHLQFFRDWTLTYLKLGIHVLCSILIGLFFGDS 391
                 :||..     |::..:...:..:|..|..|...||..||:|::..|:...:||||.:...
Mouse   378 -----SMEGC-----HSFSASCLTQFCILFKRTFLSIMRDSVLTHLRITSHIGIGLLIGLLYLGI 432

  Fly   392 GSNATKQISNVGMIMIHCVYLWYTTIMPGILRYPAEIEIIRKETFNNWYKLRTYYLATIITSTPV 456
            |:.|.|.:||.|.:....::|.:..:||.:|.:|.|:.:..:|..|.||.|:.||||..:...|.
Mouse   433 GNEAKKVLSNSGFLFFSMLFLMFAALMPTVLTFPLEMSVFLREHLNYWYSLKAYYLAKTMADVPF 497

  Fly   457 HIIFSTVYITIGYLMTDQPVEMDRFVKYLLSAVVVTICADGLGVFLGTVLNPVN-GTFVGAVSTS 520
            .|:|...|.:|.|.||.||.:..|||.:.....:.::.|..||:.:|.....:. .||||.|:..
Mouse   498 QIMFPVAYCSIVYWMTSQPSDAVRFVLFAALGTMTSLVAQSLGLLIGAASTSLQVATFVGPVTAI 562

  Fly   521 CMLMFSGFLILLNHIPAAMRFMAYISPLRYALENMVISLYGNQRGQLICPPTEFYCHFKNAVTVL 585
            .:|:||||.:..:.|||.:::|:|||.:||..|.:::|:||..|..|.|...| .|||:.:..:|
Mouse   563 PVLLFSGFFVSFDTIPAYLQWMSYISYVRYGFEGVILSIYGLDREDLHCDIAE-TCHFQKSEAIL 626

  Fly   586 RQFGMEDGDFGHNILMILIQIAIFKVLSYFTLKHKIK 622
            |:..:|:.....:.:::.|.....::::||.|::||:
Mouse   627 RELDVENAKLYLDFIVLGIFFISLRLIAYFVLRYKIR 663

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31689	NP_001259954.1	3a01204	15..622	CDD:273361	238/620 (38%)
		ABCG_EPDR	26..239	CDD:213180	113/226 (50%)
		ABC2_membrane	355..558	CDD:279410	71/203 (35%)
Abcg1	NP_033723.1	3a01204	60..666	CDD:273361	239/622 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167831336
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S2712
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D177791at33208
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48041
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	10	9.760