DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment tho2 and zc3h13

DIOPT Version :9

Sequence 1:NP_608646.3 Gene:tho2 / 326153 FlyBaseID:FBgn0031390 Length:1642 Species:Drosophila melanogaster
Sequence 2:NP_956816.2 Gene:zc3h13 / 560041 ZFINID:ZDB-GENE-040426-1619 Length:1759 Species:Danio rerio


Alignment Length:553 Identity:126/553 - (22%)
Similarity:209/553 - (37%) Gaps:156/553 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly  1212 ERKVDKVRE------------EEKTKRPDLYAIASSYIGQLKLKTPHMLKESVFHQIAERPNKES 1264
            ::..||.:|            |:|.||.|            :..:.|..|.|:..:  ||....|
Zfish   316 DKSEDKTKEGKERGRDAEKHKEKKEKRRD------------RSDSSHKAKRSMTSE--ERSGSLS 366

  Fly  1265 PTS-VGAPAAATRSDKLSPTSPSGNTQGTRAP----GGAAPFYNSEQKSVIKEPDAKAASTT-RE 1323
            |.| ..:|.|..:|....|:|...:...:|.|    ...:|....:|     .|.:::.|:. |.
Zfish   367 PPSREASPPARRKSSSPKPSSKQASQHRSRTPPRHRRSTSPSSRQQQ-----SPSSQSGSSAQRH 426

  Fly  1324 SKSQRGEGNNVTLVSTATSTASNNERESK---QRDLPAP------------RESQSRSKDDQQE- 1372
            |.|.|...:::|..::...|.|:....|.   ||| |:|            ..||.|.::.::| 
Zfish   427 SPSPRHRRSSITPSASPPPTQSSRRSRSSITPQRD-PSPASAPRRSSPSASHRSQGRERERERER 490

  Fly  1373 --------------------QANNGSNGSRQSES----RNRDV-------------ERDRHDQQD 1400
                                :..:.|.|.|:.:|    |:.|:             .|||..::|
Zfish   491 DRDRGRAEQERSPAVQERRHERRDESRGKREKDSSRDERDYDIVQSSSREERDCRDSRDRRGERD 555

  Fly  1401 QRSISSHRSSR-DIVRVKERTEAELHQRS-------RERSQRLEELEAQQRKREKTSRRGGEERI 1457
            :|.:...|..| |:...::...||..:||       |||.:..|....::|:||:|.....||.:
Zfish   556 RRDVREERQHRGDVKDTRDARAAETRERSGREPLEHRERDRDRERERERERERERTEMHRKEETM 620

  Fly  1458 R-------HGDGVETVDLVGSTDNRHYEEFE--GRMR------------DLSSVSNESNGSLHH- 1500
            .       .|.|.|.:.....||||:....|  ||.|            ..:|.::.|:.|.|. 
Zfish   621 TQEERSYGRGHGREDMRNDARTDNRNESRVERTGRGRGHGSDVTEKARGSRASQADNSSASGHDS 685

  Fly  1501 --------RQRSHE-TIEFEKVDSK---------------RRKLESSTSSSKKVEELVDSVKKAR 1541
                    |:||.| ..:.::.|.:               .|....:....::....|....:..
Zfish   686 WESRSSGLRERSTERNTDRDRYDDRPRGEQPRDERRGAHNERDRRDNREREQRAPSPVRQQNRGE 750

  Fly  1542 ALKTKERNKDKLSD----------EERDARKDRKLGRKRDRVDESNSNEHKRRREGQNGEEELRD 1596
            .|:.:||..|:.:|          .||:..:||:..|:|:| ::....|.:|.||.:...|..|:
Zfish   751 DLEREERRDDRRNDRGDDRRDDRTREREKERDRERERERER-EKEREREKEREREAERERERTRE 814

  Fly  1597 RERHREKSPRERSHEKFDRERGGASGSRAEERQ 1629
            |||.||:...||..|:.:|||......|..||:
Zfish   815 REREREREREEREREREEREREREERERERERE 847

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
tho2NP_608646.3 THOC2_N 133..627 CDD:292752
Thoc2 629..703 CDD:288568
Tho2 939..1240 CDD:288156 8/39 (21%)
PRP38_assoc 1570..1639 CDD:289628 22/60 (37%)
zc3h13NP_956816.2 zf-CCCH 49..69 CDD:279036
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1874
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.900

Return to query results.
Submit another query.