DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment tho2 and Zc3h13

DIOPT Version :9

Sequence 1:NP_608646.3 Gene:tho2 / 326153 FlyBaseID:FBgn0031390 Length:1642 Species:Drosophila melanogaster
Sequence 2:NP_001163942.1 Gene:Zc3h13 / 305955 RGDID:1307729 Length:1728 Species:Rattus norvegicus


Alignment Length:556 Identity:118/556 - (21%)
Similarity:204/556 - (36%) Gaps:165/556 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly  1212 ERKVDKVREEEKTKRPDLYAIASSYIGQLKLKTPHMLKESVFHQIAERPNKESPTSVGAPAAATR 1276
            :|..|..|:.||..:|     .||..||     .|....|..|.    .:.:|.:|:...:.:.|
  Rat   298 DRGRDFERQREKRDKP-----RSSSPGQ-----HHSPLSSRHHS----SSSQSGSSIQRHSPSPR 348

  Fly  1277 SDKLSPTSPSGNTQGTRAPG---GAAPF----YNSEQ--------KSVIKEPDAKAASTTRESKS 1326
            ..:    :||.:.|.|..|.   .|:|:    .:|.|        :|.::|........|.:|..
  Rat   349 RKR----TPSPSYQRTLTPSLRRSASPYPTHCLSSPQRKQSPPRHRSPMREKGRHDHERTSQSHD 409

  Fly  1327 QRGEGNNVTLVSTATSTASNNERESK--QRDLPAPRESQSR------------------------ 1365
            :|.|..............:..||||:  .||...||:|:.|                        
  Rat   410 RRHERREEARGKRDREKDTREERESEHDHRDDREPRDSRDRRDTRDRRELRDSRDMRDSREIRDY 474

  Fly  1366 ------SKDDQQEQANNGSNGSRQSESRN---RDVE--RDRHDQQDQRSISSHRSSRDIVRVKE- 1418
                  |:|.:..::....:..|..|:|:   |||.  ||..|.:|.|.:...|.:||:..|:: 
  Rat   475 SRDTKESRDPRDSRSARDVHDYRDREARDAHARDVRDVRDARDARDVRDVRDVRDARDVRDVRDA 539

  Fly  1419 ----------------------------------------RTEAELHQRS--RERSQRLEELEAQ 1441
                                                    :.||..:.|:  ||.|.|: ||...
  Rat   540 RDVRDARDVRDVRDVRDVRDTRDARDARDARDGHRKEDVYQEEARSYGRNHLREESSRV-ELRND 603

  Fly  1442 QRKREKTSRRGGEERIRHGDGVETVDLVG-----------STDNRHYEEFEGRM----------R 1485
            .|...::..|........|.|.|..:..|           |:.:.:::.:|.|.          |
  Rat   604 SRNESRSEIRNDRMGRSRGRGPELPEKGGRSTRGSQMDSHSSGSNYHDSWETRSSYPERDRYPER 668

  Fly  1486 DLSSVSNESNGSLHHRQRSHETIEFEKVDSKRR------------KLESSTSSSKKVEELVDSVK 1538
            |....:.:|:....|.:|       ::.|::.|            :.|......::.|..:|.|.
  Rat   669 DTRDQARDSSFERRHGER-------DRRDNRERDQRPSSPIRHQGRSEELEREERREERRIDRVD 726

  Fly  1539 KARALKTKERNKDKLSDEERDARKDRKLGRKRDRVDESNSNEHKRRREGQNGEEELRDRERHREK 1603
            :.|..:.::|::::  :.||:..:||:..|:|:: :.....|.:|.||.:...|:.|:|||.||:
  Rat   727 ERRDERVRDRDRER--ERERERERDREREREREK-ERERELERERAREREREREKERERERERER 788

  Fly  1604 SPRERSHEKFDRERGGASGSRAEERQYISKSARSSR 1639
            ..|:|.|   ||||     .|..||:...:..|..|
  Rat   789 DQRDRDH---DRER-----EREREREREKEREREER 816

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
tho2NP_608646.3 THOC2_N 133..627 CDD:292752
Thoc2 629..703 CDD:288568
Tho2 939..1240 CDD:288156 9/27 (33%)
PRP38_assoc 1570..1639 CDD:289628 23/68 (34%)
Zc3h13NP_001163942.1 zf-CCCH 42..63 CDD:279036
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1874
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

Return to query results.
Submit another query.