Protein Alignment tho2 and thoc2

DIOPT Version :9

• Sequence 1: NP_608646.3
• Gene: tho2 / 326153
• FlyBaseID: FBgn0031390
• Length: 1642
• Species: Drosophila melanogaster
• Sequence 2: XP_004916928.1
• Gene: thoc2 / 100145575
• XenbaseID: XB-GENE-980539
• Length: 1590
• Species: Xenopus tropicalis
• Alignment Length: 1689
• Identity: 688/1689 - (40%)
• Similarity: 974/1689 - (57%)
• Gaps: 241/1689 - (14%)

  Fly    59 TLNP-EVFKHLDKSGRSEFLKYLKHQLQDAADTPVYDKNGVFKQGISNAIYQLLWQTLRFTHKKD 122
            ||.| :..|:.:|||:::||:..:...:...:...:.:       |...:|:...|.::...|:|
 Frog     4 TLLPADWIKNWEKSGKNDFLQLCRSLSEKGQELVTFTE-------IQQVLYEFACQVVKGNLKQD 61

  Fly   123 IVLHLLLEVVALHADFPSLIVDVVNILDSETSLITDGLQEE--RHAFVQLVKDLDRVIPESLLKE 185
            .|..:|.|::|...|.||::.||..|||.|||    .|:|:  |..|.|||.....:|.:::|||
 Frog    62 QVSGVLAEIIAFRDDMPSVLADVFCILDIETS----SLEEKWRRDHFTQLVSSCLYLISDTILKE 122

  Fly   186 RLEIDTLQEAGIVK-NKSFYSKFIKVKTKLYYKQRRFNLFREESEGFAKLITELNQEFDENTTPE 249
            ||:.|||:..|::| ::.|..|.:|:||||:|||::|||.|||:||:|||||||.|:...:.|.:
 Frog   123 RLDPDTLESLGLIKQSQQFNQKSVKIKTKLFYKQQKFNLLREENEGYAKLITELGQDLSGSITSD 187

  Fly   250 SIMDIIKSLIGCFNLDPNRVLDIIIESFETRPDRWNLFIPLLRSYM----PTGAIICEVLGYKFC 310
            .|::.|||||||||||||||||||:|.:|.||:..:.|.||:.|||    |  ..:|.:||:||.
 Frog   188 LILENIKSLIGCFNLDPNRVLDIILEVYECRPNHDDFFAPLIESYMCMCEP--QTLCHILGFKFK 250

  Fly   311 HFKD--SRTPRSLYHVCALLLKHGVIALNDVYVWLTPNDGSIKADWEEDLADAREMVRKLNL-IQ 372
            .:::  ..||.|||.|.|:||::.:|.|.|:||.|.|.:.:|..:.:.::.:|:::||||.: :.
 Frog   251 FYQEPSGETPSSLYRVAAVLLQNNLIELEDLYVHLLPAESTIIEEHKREVIEAKQIVRKLTMVVL 315

  Fly   373 TNKKEDEKDPPPPPSVKKFNEEKYNA---NQKFGLCEALLKVGDWENAYKIIQKLPEQAVVLQEP 434
            |:.|.:|||     ..|:.:|||...   |||.||.|:||::|||::|..|:.::|.......:|
 Frog   316 TSDKTEEKD-----KEKEKDEEKTEKPPDNQKLGLLESLLRIGDWQHAQSIMDQMPPYYAASHKP 375

  Fly   435 IARAIADLIHLSVENIYYKKCFKAPAGRRPSRNRLYEDSKLVAKMQAKEFGDLRKYTWPMANVLG 499
            ||.|:.||||.:::.:|.:.  ..|.|.:.||.......|  |...|:.|.|||:..:.|...||
 Frog   376 IAVALCDLIHKTIDPLYRRS--GVPKGAKGSRIVPLHSKK--APKPAETFEDLRRDAFTMLCYLG 436

  Fly   500 PAMHYDTVLMYKLIRIMRKLVVDMGVDSLNGPPPNSEAEQH----YYDIMSSLDACILPSLLYLD 560
            |.:.:|.:|:.|::|:.:.|:.::..::      |.|.::.    :..::|..|..:||:|..:|
 Frog   437 PHLSHDPILLAKIVRLGKALMKELQSEA------NIEEKEKMEILFSCLLSVTDQVLLPALTLMD 495

  Fly   561 NNCSMSEEIWAVLKYFPYHFRYSLYARWKNDSYQLHPNLIRRCGLAQRDIKALMKRVSKENVKQL 625
            .|..||||:|.:.|.|||.:||.||.:|||::|..||.|::.........|.:|||::|||:|..
 Frog   496 CNACMSEELWGMFKCFPYQYRYRLYGQWKNETYNSHPLLVKVKAQTIDRAKYIMKRLTKENIKPS 560

  Fly   626 GRLVGKYSHCAPGLLFDYILLQIQIYDNLIGPVCDLLKYLTALSFDCLGYCIIESLTLTGRLRFK 690
            ||.:||.||..|.:||||||.|||.|||||.||.|.|||||:|::|.|.|||||:|....:.:.|
 Frog   561 GRQIGKLSHSNPTILFDYILSQIQKYDNLITPVVDSLKYLTSLNYDVLAYCIIEALANPEKEKMK 625

  Fly   691 DDGTSLSLWLQSLASFCGTIYKKYSIELSGLLQYVANQLKSQKSLDLLILREIVHKMAGVESCEE 755
            .|.|::|.||||||||||.|::||.|||.|||||||||||:.||.|||||:|:|.||||:|..||
 Frog   626 HDDTTISSWLQSLASFCGAIFRKYPIELGGLLQYVANQLKAGKSFDLLILKEVVQKMAGIEITEE 690

  Fly   756 MTNDQLQAMCGGEQLRGEAGYFSQVRNTKKSSNRLKEALANNDLAVAICLLMAQQKHCVIYRETA 820
            ||.:||:||.|||||:.|.|||.|:|||||||.|||:||...:||:.:|||||||::.|:::| .
 Frog   691 MTMEQLEAMTGGEQLKAEGGYFGQIRNTKKSSQRLKDALLEYELALPLCLLMAQQRNGVVFQE-G 754

  Fly   821 AHSHLKLVGNLYDQCQDTLVQFGTFLGSTYSVDEYVERLPSIITMLREYHINTDVAFFLARPMFT 885
            ...||||||.|||||.|||||||.||.|..|.::|::|:|||..:..|:|...|.||||:|||:.
 Frog   755 GEKHLKLVGKLYDQCHDTLVQFGGFLASNLSTEDYIKRVPSIDFLCNEFHTPHDAAFFLSRPMYA 819

  Fly   886 HQINQKYDQLRKDDPNAKKLTTTQKLQKYLEATQLIMNPIVESVRPLHSSKVWEDISPQFLVTFW 950
            |.|:.|||:|:|.:...|:   ..|:.||:.:..|:|:|:.|:|..||..||||||||||..|||
 Frog   820 HHISSKYDELKKAEKGNKQ---QHKVHKYITSCDLVMSPVHEAVISLHPPKVWEDISPQFYATFW 881

  Fly   951 SLSMYDLHVPNESYQREVAKLKQLAQQAAEGKDSNQSKNKKEQERYIALMEKLNDERKKQHEHVD 1015
            ||:||||.||:.||.||:.|||...:...|..|...:|.|||:||..||.|||.:|.|||.|||.
 Frog   882 SLTMYDLAVPSNSYNREINKLKSQMRAIDENMDMPPNKKKKEKERCTALQEKLVEEEKKQSEHVA 946

  Fly  1016 KISQRLQEQKDSWFLLRSGKSAKNDTITQFLQLCLFPRCTFTALDALYCAKFVHTIHNLKTSNFS 1080
            ::.||::.:||:|.|.|   |.||:|||:|||||:||||.|:|:||:|||:||..:|..||.|||
 Frog   947 RVLQRMKLEKDNWLLAR---STKNETITKFLQLCIFPRCIFSAIDAVYCARFVELVHLQKTPNFS 1008

  Fly  1081 TLLCYDRIFCDITYSVTSCTEGEATRYGRFLCAMLETVMRWHADQAVFNKECANYPGFVTKFRVS 1145
            |||||||:|.||.|:|.||||.||:|||||||.|||||.:||.|:||::|:|.:||||||..|.:
 Frog  1009 TLLCYDRVFSDIIYTVASCTENEASRYGRFLCCMLETVTKWHGDRAVYDKDCGSYPGFVTILRAA 1073

  Fly  1146 NQFSEAN--DHVGYENYRHVCHKWHYKITKAIVFCLDSKDFMQIRNALIILMRILPHYPVLSKLA 1208
            : |...|  |.:.|||:|||.||||||:|||.|.||::.::..|||.||:|.:|||.||.:..|.
 Frog  1074 S-FDSGNKADQLDYENFRHVVHKWHYKLTKASVHCLETGEYTHIRNILIVLTKILPWYPKVLNLG 1137

  Fly  1209 QIIERKVDKVREEEKTKRPDLYAIASSYIGQLKLKTPHMLKESVFHQ------------------ 1255
            |.:||:|.|:.::||.|||||||:|..|.||||.:...|:.|:.||.
 Frog  1138 QALERRVHKICQDEKEKRPDLYALAMGYSGQLKSRKHFMVPENDFHHKDPPVRSSVPPPVQNGPG 1202

  Fly  1256 ------------------IAERPNKESPTSVGAPAAATRSDKLSP--TSPSGNTQG--------- 1291
                              ..|...|....|..|....|::...:|  |:.:||:..
 Frog  1203 ISNQSASMLANAAKPEEGTTEETEKIKEKSQSALKVVTKAASTAPKVTASNGNSASSSKVLKEKE 1267

  Fly  1292 -----------------------TRAPGGAAPFYNSEQKSV-------IKEPDAKA----ASTTR 1322
                                   |:|||..|.....|.:|.       .||...||    ....:
 Frog  1268 DKDKTGKEKEKDKREKTPVAPLETKAPGKEAKEKAKEDRSSKDEKLRDAKEKTPKADKEKEKAKK 1332

  Fly  1323 ESKSQRGEGNNVTLVSTATSTASNNERESK-QRDLPAPRESQSRSKDDQQEQANNGSNGSRQSES 1386
            |.|||:.:.:...|:|..:...|..|||.: .|:..|.:|.:|:......::|  ..:||.:|..
 Frog  1333 EEKSQKEDKSKAVLMSNESKVPSEKEREKELSREKEALKEVKSKENSKSGDKA--AVSGSLKSPV 1395

  Fly  1387 RNRDV-ERDRHDQQDQRSISSHRSSRDIVRVKE-----------------------RTEAELHQ- 1426
            ...|: |.:|  :|.:|.|.:|.|......||:                       ..|.|:.:
 Frog  1396 PRTDMTETER--EQKRRKIDTHSSPSHSSAVKDNLSEFKDSSAKHYTNHTTPAISKNKEKEVEKK 1458

  Fly  1427 ---RSRERSQRLEELEAQQRKREKTSRRGGEERIRHGDGVETVDLVGSTDNRHYEEFEGRMRDLS 1488
               :|||||:..|:.|.::||..|                                     ||
 Frog  1459 ELDKSRERSREREKKEEKERKERK-------------------------------------RD-- 1484

  Fly  1489 SVSNESNGSLHHRQRSHETIEFEKVDSKRRKLESSTSSS---KKVEELVDSVKKARALKTKERNK 1550
                .|||       ..|.::    :|||||.|:.||.|   .|.|...||.:.:.    |||||
 Frog  1485 ----HSNG-------DRELLQ----ESKRRKEENGTSGSSKHSKSESPSDSPRSSE----KERNK 1530

  Fly  1551 DKLSDEER-DARKDRKL-----GRKRDRVDESNSNEHKRRREGQNGEEELRDRERHREKSPRER 1608
            .|.|.:|: |..|..|:     |.|::...:...:|.|.:||...|:||    ::|.:.|.:.|
 Frog  1531 SKSSSKEKGDFMKSEKMEKSSSGSKKESRHDKEKSEKKEKRESTGGKEE----KKHHKSSDKHR 1590

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tho2	NP_608646.3	THOC2_N	133..627	CDD:292752	204/510 (40%)
		Thoc2	629..703	CDD:288568	43/73 (59%)
		Tho2	939..1240	CDD:288156	176/302 (58%)
		PRP38_assoc	1570..1639	CDD:289628	10/39 (26%)
thoc2	XP_004916928.1	THOC2_N	11..562	CDD:374385	218/578 (38%)
		Thoc2	564..638	CDD:371698	43/73 (59%)
		Tho2	870..1169	CDD:371438	176/302 (58%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	377	1.000	Domainoid score	I854
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H69669
Inparanoid	1	1.050	1164	1.000	Inparanoid score	I203
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D979205at2759
OrthoFinder	1	1.000	-	-		FOG0003449
OrthoInspector	1	1.000	-	-		oto103299
Panther	1	1.100	-	-	LDO	PTHR21597
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2346
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.160