DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment erm and NUC

DIOPT Version :9

Sequence 1:	NP_001259891.2	Gene:	erm / 326152	FlyBaseID:	FBgn0031375	Length:	698	Species:	Drosophila melanogaster
Sequence 2:	NP_199229.1	Gene:	NUC / 834439	AraportID:	AT5G44160	Length:	466	Species:	Arabidopsis thaliana

Alignment Length:	470	Identity:	93/470 - (19%)
Similarity:	147/470 - (31%)	Gaps:	162/470 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   249 SPVAQRTAQSSGLQANLKRKRSPQDQGEVTPPPASTATSATGARSRSPSPQGSIEDSSPGSASGG 313
            |.|.|..:..||............|:..:.||......:..|    :|.|:..:...||
plant     3 SEVLQTISSGSGFAQPQSSSTLDHDESLINPPLVKKKRNLPG----NPDPEAEVIALSP------ 57

  Fly   314 KPKTFSCLECGKVFNAHYNLTRHMPVHTGARPFVCKVCGKGFRQASTLCRHKIIH---------T 369
                                |..|..:.    |:|:||||||::...|..|:..|         |
plant    58 --------------------TTLMATNR----FLCEVCGKGFQRDQNLQLHRRGHNLPWKLKQRT 98

  Fly   370 SEKPHK----C--QTC-----GKAFNRSSTLNTHSRIHAGYKPFVCEYCGKGFHQKGNYKNHKLT 423
            |::..|    |  :||     .:|....:.:..|.....|.|.:.||.|.|.:..:.::|.|..|
plant    99 SKEVRKRVYVCPEKTCVHHHSSRALGDLTGIKKHFCRKHGEKKWTCEKCAKRYAVQSDWKAHSKT 163

  Fly   424 HSGEKAYKCNICNKAFHQVYNLTFHMHTHNDKKPYTCRVCAKGFCRNFDLKKHMRKLHEIGGDLD 488
             .|.:.|:|: |...|.:..:...|                :.||.  .|.:...|::.:
plant   164 -CGTREYRCD-CGTIFSRRDSFITH----------------RAFCD--ALAEETAKINAV----- 203

  Fly   489 DLDMPPTYDRRREYTRREPLASGYGQASGQLTPDSSSGSMSPPINVTTPPLSSGETSNPAWPRSA 553
                          :....||:.....|..|......|:..||:.    |......:||
plant   204 --------------SHLNGLAAAGAPGSVNLNYQYLMGTFIPPLQ----PFVPQPQTNP------ 244

  Fly   554 VSQYPPGGFHHQLGVAPPHDYPSGSAFLQL------QPQQPHPQSQQHHQQQQRLSETFIAKVFX 612
                   ..|||      |..|..|:.|.|      .|.||.|....               ||.
plant   245 -------NHHHQ------HFQPPTSSSLSLWMGQDIAPPQPQPDYDW---------------VFG 281

  Fly   613 QRYYAESL--NSSTGS---TSTTSSTVTTTTTAISSMATSRSDLLIDXLQFVAAAAAASSSNSGQ 672
            ....|.:.  |::|..   |...::::|||||                    .:|.:..||:..|
plant   282 NAKAASACIDNNNTHDEQITQNANASLTTTTT--------------------LSAPSLFSSDQPQ 326

  Fly   673 DTGESPSPELGCTAL 687
            :...:.:..:..|||
plant   327 NANANSNVNMSATAL 341

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
erm	NP_001259891.2	COG5048	<295..461	CDD:227381	40/185 (22%)
		C2H2 Zn finger	320..340	CDD:275368	2/19 (11%)
		zf-H2C2_2	332..357	CDD:290200	10/24 (42%)
		zf-C2H2	346..368	CDD:278523	10/21 (48%)
		C2H2 Zn finger	348..368	CDD:275368	9/19 (47%)
		zf-H2C2_2	363..385	CDD:290200	9/41 (22%)
		C2H2 Zn finger	376..396	CDD:275368	5/26 (19%)
		zf-H2C2_2	389..413	CDD:290200	7/23 (30%)
		C2H2 Zn finger	404..424	CDD:275368	6/19 (32%)
		zf-H2C2_2	416..441	CDD:290200	8/24 (33%)
		C2H2 Zn finger	432..452	CDD:275368	4/19 (21%)
		C2H2 Zn finger	460..478	CDD:275368	3/17 (18%)
NUC	NP_199229.1	C2H2 Zn finger	68..88	CDD:275368	9/19 (47%)
		C2H2 Zn finger	109..137	CDD:275368	5/27 (19%)
		C2H2 Zn finger	144..163	CDD:275368	6/18 (33%)
		C2H2 Zn finger	171..187	CDD:275368	4/32 (13%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910