DRSC/TRiP Functional Genomics Resources

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Protein Alignment erm and ZSCAN5C

DIOPT Version :9

Sequence 1:NP_001259891.2 Gene:erm / 326152 FlyBaseID:FBgn0031375 Length:698 Species:Drosophila melanogaster
Sequence 2:NP_001345342.1 Gene:ZSCAN5C / 649137 HGNCID:34294 Length:496 Species:Homo sapiens


Alignment Length:516 Identity:130/516 - (25%)
Similarity:189/516 - (36%) Gaps:112/516 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly    16 GEIAMMPPSKSPVMESAASEQNPAQQSQQQDEQSAKRACPLKF-------------SIAKIME-- 65
            ||....|.|:.|       :..|:..:|..:..|....|.:.|             ::.|:.|  
Human    12 GESCNSPGSEPP-------QSMPSPATQLGNHDSDPETCHVNFRMFSCPKESDPIQALRKLTELC 69

  Fly    66 -----PD-HRPSQ-----------VPPPQPAPVSFATNDDDEDEDPEIDADSERSCSPIEVIS-- 111
                 || |...|           :..||...|....|.....:|.|....:.|......|:|  
Human    70 HLWLRPDLHTKEQILDMLVMEQFMISMPQELQVLVMMNGVQSCKDLEDLLRNNRRPKKWSVVSFL 134

  Fly   112 ------------LDQSPSTVNYDSAFKKYVPGPCSGATSSVASPPSTAAVQQFVSSRHQELLSQY 164
                        :.::|::|..|   .::|   .|..||||    :....::..:|:..:.|.:.
Human   135 GKEYLMQESDVEMAEAPASVRDD---PRHV---SSQRTSSV----NQMCPEEGQASQELQTLPRV 189

  Fly   165 PLLYYAPNQ--LMCAAAAAQYAALTAQQQSLASAAHLSSFTASLNASLHHSQSLRRNLGHP---- 223
            |.|:....:  |:     .:...:....::|..       ..:|...|...:.....|..|    
Human   190 PALFRRQEEDFLL-----PETTVMKGDPKALRP-------KPTLEKDLEEDREENPGLTSPEPQL 242

  Fly   224 ------LAAAAAVAAVAQSQAVPNLQHTLEKSPVAQRTAQ----SSGLQANLK-RKRSPQD---- 273
                  :..|.......:..:|.|:......:.|.:|.|.    |.|...||: .|||..|    
Human   243 PNSPTGVVGAKEGKEPQKRASVENVDADTPSACVVEREASTHSGSRGDALNLRGLKRSKPDATSI 307

  Fly   274 -----QGEVTP-----PPASTATSATGARSRSPSPQGSIEDSSPGSASGGKPKTFSCLECGKVFN 328
                 |||.||     .|.....:..    .||.|.|.:  |.|......:...|:|..|||.|.
Human   308 SQEEPQGEATPVGNRESPGQAEINPV----HSPGPAGPV--SHPSGQEVKELLPFACEVCGKRFK 366

  Fly   329 AHYNLTRHMPVHTGARPFVCKVCGKGFRQASTLCRHKIIHTSEKPHKCQTCGKAFNRSSTLNTHS 393
            ....|..|...|||.|.|.|.:|||.|.|...|..|:..||.|:|:.|..|.|.|.:.|.|..|.
Human   367 YRGKLAVHTRSHTGERLFQCNLCGKRFMQRIGLQFHQRTHTGERPYTCDICQKQFTQKSYLKCHK 431

  Fly   394 RIHAGYKPFVCEYCGKGFHQKGNYKNHKLTHSGEKAYKCNICNKAFHQVYNLTFHMHTHND 454
            |.|.|.|||.|:.|.|.|..|.|.|.|:..|||||.:||:.|.:||.:...|..|..||.:
Human   432 RSHTGEKPFECKDCKKVFTYKANLKEHQRIHSGEKPHKCSKCPRAFGRPATLRRHQKTHRE 492

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ermNP_001259891.2 COG5048 <295..461 CDD:227381 66/160 (41%)
C2H2 Zn finger 320..340 CDD:275368 7/19 (37%)
zf-H2C2_2 332..357 CDD:290200 12/24 (50%)
zf-C2H2 346..368 CDD:278523 9/21 (43%)
C2H2 Zn finger 348..368 CDD:275368 8/19 (42%)
zf-H2C2_2 363..385 CDD:290200 9/21 (43%)
C2H2 Zn finger 376..396 CDD:275368 8/19 (42%)
zf-H2C2_2 389..413 CDD:290200 12/23 (52%)
C2H2 Zn finger 404..424 CDD:275368 8/19 (42%)
zf-H2C2_2 416..441 CDD:290200 13/24 (54%)
C2H2 Zn finger 432..452 CDD:275368 6/19 (32%)
C2H2 Zn finger 460..478 CDD:275368
ZSCAN5CNP_001345342.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..38 7/32 (22%)
SCAN 40..124 CDD:153421 14/83 (17%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 149..188 11/48 (23%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 203..347 31/156 (20%)
zf-C2H2 356..378 CDD:333835 8/21 (38%)
C2H2 Zn finger 358..378 CDD:275368 7/19 (37%)
zf-H2C2_2 371..393 CDD:372612 11/21 (52%)
C2H2 Zn finger 386..406 CDD:275368 8/19 (42%)
COG5048 410..>473 CDD:227381 29/62 (47%)
C2H2 Zn finger 414..434 CDD:275368 8/19 (42%)
C2H2 Zn finger 442..462 CDD:275368 8/19 (42%)
zf-C2H2 468..490 CDD:333835 7/21 (33%)
C2H2 Zn finger 470..490 CDD:275368 6/19 (32%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

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