DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment erm and gfi1aa

DIOPT Version :9

Sequence 1:	NP_001259891.2	Gene:	erm / 326152	FlyBaseID:	FBgn0031375	Length:	698	Species:	Drosophila melanogaster
Sequence 2:	NP_001018612.1	Gene:	gfi1aa / 553814	ZFINID:	ZDB-GENE-050522-534	Length:	385	Species:	Danio rerio

Alignment Length:	272	Identity:	93/272 - (34%)
Similarity:	137/272 - (50%)	Gaps:	38/272 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   236 SQAVPNLQHTLEK-SPVAQRTAQSSGLQANLKRKRSP-------------QDQGEVTPP------ 280
            |.:...|:|.::. :.|:..:..|.|:...:.|:.|.             ||.|.:||.
Zfish   123 SHSSSELRHLIQSCNRVSVDSDSSVGVYDAMDRRSSAHLLIQPTQSRRFYQDYGSLTPNLLDNRG 187

  Fly   281 -----PASTATSATGARSRSPSPQGSIEDSSPGSASGGKPKTFSCLECGKVFNAHYNLTRHM-PV 339
                 ..||..:.|.:.|.....:..:..|            :.|::|.|||:..:.|..|: ..
Zfish   188 FYTDFKMSTKVAETDSESDMTCTRLQLSGS------------YKCIKCTKVFSTPHGLEVHVRRS 240

  Fly   340 HTGARPFVCKVCGKGFRQASTLCRHKIIHTSEKPHKCQTCGKAFNRSSTLNTHSRIHAGYKPFVC 404
            |:|.|||.|::|||.|..|.:|.:||.:|:.|:...|:.|.|:|.|||||:||..||:..:|:.|
Zfish   241 HSGTRPFACEICGKTFGHAVSLEQHKAVHSQERVFSCKICDKSFKRSSTLSTHLLIHSDTRPYPC 305

  Fly   405 EYCGKGFHQKGNYKNHKLTHSGEKAYKCNICNKAFHQVYNLTFHMHTHNDKKPYTCRVCAKGFCR 469
            :||||.||||.:.|.|...|:|||.:||.:|.|||.|..||..|...|...||:.|.:|.|||.|
Zfish   306 QYCGKRFHQKSDMKKHTFIHTGEKPHKCQVCGKAFSQSSNLITHSRKHTGFKPFGCDLCGKGFQR 370

  Fly   470 NFDLKKHMRKLH 481
            ..||::|....|
Zfish   371 KVDLRRHKETQH 382

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
erm	NP_001259891.2	COG5048	<295..461	CDD:227381	66/166 (40%)
		C2H2 Zn finger	320..340	CDD:275368	7/20 (35%)
		zf-H2C2_2	332..357	CDD:290200	12/25 (48%)
		zf-C2H2	346..368	CDD:278523	10/21 (48%)
		C2H2 Zn finger	348..368	CDD:275368	9/19 (47%)
		zf-H2C2_2	363..385	CDD:290200	8/21 (38%)
		C2H2 Zn finger	376..396	CDD:275368	11/19 (58%)
		zf-H2C2_2	389..413	CDD:290200	12/23 (52%)
		C2H2 Zn finger	404..424	CDD:275368	11/19 (58%)
		zf-H2C2_2	416..441	CDD:290200	12/24 (50%)
		C2H2 Zn finger	432..452	CDD:275368	9/19 (47%)
		C2H2 Zn finger	460..478	CDD:275368	9/17 (53%)
gfi1aa	NP_001018612.1	C2H2 Zn finger	220..241	CDD:275368	7/20 (35%)
		C2H2 Zn finger	249..269	CDD:275368	9/19 (47%)
		zf-H2C2_2	261..286	CDD:290200	9/24 (38%)
		C2H2 Zn finger	277..297	CDD:275368	11/19 (58%)
		C2H2 Zn finger	305..325	CDD:275368	11/19 (58%)
		zf-H2C2_2	317..342	CDD:290200	12/24 (50%)
		C2H2 Zn finger	333..353	CDD:275368	9/19 (47%)
		C2H2 Zn finger	361..380	CDD:275368	9/18 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910