DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment erm and osr2

DIOPT Version :9

Sequence 1:NP_001259891.2 Gene:erm / 326152 FlyBaseID:FBgn0031375 Length:698 Species:Drosophila melanogaster
Sequence 2:XP_005173612.1 Gene:osr2 / 550389 ZFINID:ZDB-GENE-050417-183 Length:278 Species:Danio rerio


Alignment Length:299 Identity:90/299 - (30%)
Similarity:119/299 - (39%) Gaps:81/299 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly   199 LSSFTASLN-----ASLHHSQSLRRNLGH---------------PLAAAAAVAAVAQSQAVPNLQ 243
            |::|..:::     ::||..|..|..:|.               |..||||              
Zfish    26 LNAFPVAVDQLYGLSALHTVQMNRWTVGFPQLQGLADPRFPGALPFPAAAA-------------- 76

  Fly   244 HTL-EKSPVAQRTAQSSGLQANLKRKRSPQDQGEVTPPPASTATSATGARSRSPSPQGSIEDSSP 307
            |.| .|.||.::....... |||....:.:|      ||      .||....||..:     .:.
Zfish    77 HLLPHKHPVHRKDRPRFDF-ANLAVAATQED------PP------VTGQSRLSPERR-----PAR 123

  Fly   308 GSASGGKPKTFSCLECGKVFNAHYNLTRHMPVHTGARPFVCKVCGKGFRQASTLCRHKIIHTSEK 372
            |.......|.|.|..||:.|...|||..|...||..||:.|.:|.|.||:...|..|:.||:.||
Zfish   124 GRLPAKSKKEFICRFCGRHFTKSYNLLIHERTHTDERPYTCDICHKAFRRQDHLRDHRYIHSKEK 188

  Fly   373 PHKCQTCGKAFNRSSTLNTHSRIHAGYKPFVCEYCGKGFHQKGNYKNHKLTHSGEKAYKCNICNK 437
            |.|||.|||.|.:|.||..|..:|....|..|..||:.|:|:.|.|.|.|||:            
Zfish   189 PFKCQECGKGFCQSRTLAVHKTLHLQESPHKCPTCGRTFNQRSNLKTHLLTHT------------ 241

  Fly   438 AFHQVYNLTFHMHTHNDKKPYTCRVCAKGFCRNFDLKKH 476
                            |.||:.|..|.|.|.||.||::|
Zfish   242 ----------------DLKPFCCGRCGKVFRRNCDLRRH 264

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ermNP_001259891.2 COG5048 <295..461 CDD:227381 56/165 (34%)
C2H2 Zn finger 320..340 CDD:275368 8/19 (42%)
zf-H2C2_2 332..357 CDD:290200 11/24 (46%)
zf-C2H2 346..368 CDD:278523 7/21 (33%)
C2H2 Zn finger 348..368 CDD:275368 7/19 (37%)
zf-H2C2_2 363..385 CDD:290200 13/21 (62%)
C2H2 Zn finger 376..396 CDD:275368 10/19 (53%)
zf-H2C2_2 389..413 CDD:290200 8/23 (35%)
C2H2 Zn finger 404..424 CDD:275368 9/19 (47%)
zf-H2C2_2 416..441 CDD:290200 6/24 (25%)
C2H2 Zn finger 432..452 CDD:275368 0/19 (0%)
C2H2 Zn finger 460..478 CDD:275368 9/17 (53%)
osr2XP_005173612.1 COG5048 <55..>276 CDD:227381 83/270 (31%)
C2H2 Zn finger 136..156 CDD:275368 8/19 (42%)
zf-H2C2_2 148..173 CDD:290200 11/24 (46%)
C2H2 Zn finger 164..184 CDD:275368 7/19 (37%)
zf-H2C2_2 176..199 CDD:290200 13/22 (59%)
C2H2 Zn finger 192..212 CDD:275368 10/19 (53%)
zf-C2H2 218..240 CDD:278523 9/21 (43%)
C2H2 Zn finger 220..240 CDD:275368 9/19 (47%)
C2H2 Zn finger 248..268 CDD:275368 9/17 (53%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
00.000

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