Protein Alignment erm and ZNF580

DIOPT Version :10

• Sequence 1: NP_001259891.2
• Gene: erm / 326152
• FlyBaseID: FBgn0031375
• Length: 698
• Species: Drosophila melanogaster
• Sequence 2: NP_057286.1
• Gene: ZNF580 / 51157
• HGNCID: 29473
• Length: 172
• Species: Homo sapiens
• Alignment Length: 168
• Identity: 49/168 - (29%)
• Similarity: 67/168 - (39%)
• Gaps: 45/168 - (26%)

  Fly   267 RKRSPQDQGEVTPP----------PASTATSATGAR--------------------------SRS 295
            |..||:.. :..||          |:||.:||.|.|                          .|.
Human    12 RSSSPEAM-DPPPPKAPPFPKAEGPSSTPSSAAGPRPPRLGRHLLIDANGVPYTYTVQLEEEPRG 75

  Fly   296 PSPQGSIEDSSPGSASGGKPKTFSCLECGKVFNAHYNLTRHMPVHTGARPFVCKVCGKGFRQAST 360
            | ||.......||...|     :||.||.:||.:...|..|...|:..:||.|..|||.|:::|.
Human    76 P-PQREAPPGEPGPRKG-----YSCPECARVFASPLRLQSHRVSHSDLKPFTCGACGKAFKRSSH 134

  Fly   361 LCRHKIIHTSE--KPHKCQTCGKAFNRSSTLNTHSRIH 396
            |.||:..|.:.  .||.|..|.:.|..::.|..|.|:|
Human   135 LSRHRATHRARAGPPHTCPLCPRRFQDAAELAQHVRLH 172

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
erm	NP_001259891.2	COG5048	<295..461	CDD:227381	36/104 (35%)
		C2H2 Zn finger	320..340	CDD:275368	7/19 (37%)
		C2H2 Zn finger	348..368	CDD:275368	9/19 (47%)
		zf-H2C2_2	363..385	CDD:463886	8/23 (35%)
		C2H2 Zn finger	376..396	CDD:275368	6/19 (32%)
		C2H2 Zn finger	404..424	CDD:275368
		C2H2 Zn finger	432..452	CDD:275368
		C2H2 Zn finger	460..478	CDD:275368
ZNF580	NP_057286.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..93		19/87 (22%)
		C2H2 Zn finger	94..114	CDD:275368	7/19 (37%)
		zf-C2H2	120..142	CDD:395048	10/21 (48%)
		C2H2 Zn finger	122..142	CDD:275368	9/19 (47%)
		C2H2 Zn finger	152..172	CDD:275368	6/19 (32%)