DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment erm and osr1

DIOPT Version :9

Sequence 1:	NP_001259891.2	Gene:	erm / 326152	FlyBaseID:	FBgn0031375	Length:	698	Species:	Drosophila melanogaster
Sequence 2:	NP_001006079.1	Gene:	osr1 / 450059	ZFINID:	ZDB-GENE-070321-1	Length:	264	Species:	Danio rerio

Alignment Length:	264	Identity:	80/264 - (30%)
Similarity:	106/264 - (40%)	Gaps:	48/264 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   170 APNQLMCAAAAAQYAALTAQQQSLASAAHLS---SFTASLNASLHHSQSLRRNLGHP-------- 223
            ||..|..:...|.|:.|.........|.|:.   ||:|.....||     :..||:|
Zfish     8 APVPLHPSLQLANYSFLQTSNGLHLPADHMPSIYSFSALHAVHLH-----QWTLGYPPFTLPRCT 67

  Fly   224 -LAAAAAVAAVAQSQAVPNLQHTLEKSPVAQRTAQSSGLQANLKRKRSPQ-DQGEVTPPPASTAT 286
             ......|.|.....::|...|.::  |..|   :|||..:....|..|: |...:    |:.||
Zfish    68 FSKLPGLVDARFPLPSIPLFPHLVQ--PAKQ---ESSGPGSGASSKSKPRFDFANL----AAAAT 123

  Fly   287 ----------SATGARSRSPSPQGSIEDSSPGSASGGKP----------KTFSCLECGKVFNAHY 331
                      |......|||| .|.:.|.:..|:...||          |.|.|..||:.|...|
Zfish   124 QDDALKAEDLSTNNGHVRSPS-LGCLLDVAKLSSPERKPSRGRLPSKTKKEFVCKFCGRHFTKSY 187

  Fly   332 NLTRHMPVHTGARPFVCKVCGKGFRQASTLCRHKIIHTSEKPHKCQTCGKAFNRSSTLNTHSRIH 396
            ||..|...||..||:.|.:|.|.||:...|..|:.||:.|||.|||.|||.|.:|.||..|..:|
Zfish   188 NLLIHERTHTDERPYTCDICHKAFRRQDHLRDHRYIHSKEKPFKCQECGKGFCQSRTLAVHKTLH 252

  Fly   397 AGYK 400
            ...|
Zfish   253 MQVK 256

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
erm	NP_001259891.2	COG5048	<295..461	CDD:227381	47/116 (41%)
		C2H2 Zn finger	320..340	CDD:275368	8/19 (42%)
		zf-H2C2_2	332..357	CDD:290200	11/24 (46%)
		zf-C2H2	346..368	CDD:278523	7/21 (33%)
		C2H2 Zn finger	348..368	CDD:275368	7/19 (37%)
		zf-H2C2_2	363..385	CDD:290200	13/21 (62%)
		C2H2 Zn finger	376..396	CDD:275368	10/19 (53%)
		zf-H2C2_2	389..413	CDD:290200	4/12 (33%)
		C2H2 Zn finger	404..424	CDD:275368
		zf-H2C2_2	416..441	CDD:290200
		C2H2 Zn finger	432..452	CDD:275368
		C2H2 Zn finger	460..478	CDD:275368
osr1	NP_001006079.1	zf-C2H2	174..196	CDD:278523	9/21 (43%)
		C2H2 Zn finger	176..196	CDD:275368	8/19 (42%)
		zf-H2C2_2	188..213	CDD:290200	11/24 (46%)
		C2H2 Zn finger	204..224	CDD:275368	7/19 (37%)
		zf-H2C2_2	216..239	CDD:290200	13/22 (59%)
		C2H2 Zn finger	232..252	CDD:275368	10/19 (53%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	0	0.000