DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment erm and Zfp992

DIOPT Version :9

Sequence 1:	NP_001259891.2	Gene:	erm / 326152	FlyBaseID:	FBgn0031375	Length:	698	Species:	Drosophila melanogaster
Sequence 2:	NP_001078991.1	Gene:	Zfp992 / 433791	MGIID:	3700963	Length:	573	Species:	Mus musculus

Alignment Length:	168	Identity:	71/168 - (42%)
Similarity:	96/168 - (57%)	Gaps:	2/168 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly   311 SGGKPKTFSCLECGKVFNAHYNLTRHMPVHTGARPFVCKVCGKGFRQASTLCRHKIIHTSEKPHK 375
            :|.||  :.|.||.|.|....:|..|..:|||.:|:.|.||.|.|.:...|..|:.|||.:||:|
Mouse   263 TGEKP--YKCSECDKCFTQKSHLNIHQRIHTGEKPYKCIVCEKCFTEKGNLRIHQRIHTGDKPYK 325

  Fly   376 CQTCGKAFNRSSTLNTHSRIHAGYKPFVCEYCGKGFHQKGNYKNHKLTHSGEKAYKCNICNKAFH 440
            |..|.|.|.:.|.||.|.|||.|.||:.|..|.|.|.:.|:.:.|:..|:|||.|||:.|:|:|.
Mouse   326 CSECDKCFTQKSHLNIHQRIHTGEKPYKCSKCDKSFTENGHLRIHQRNHTGEKPYKCSQCDKSFT 390

  Fly   441 QVYNLTFHMHTHNDKKPYTCRVCAKGFCRNFDLKKHMR 478
            :..:|..|...|..:|||.|..|.|.|.:.|.|:.|.|
Mouse   391 ENGHLRIHQRIHTGEKPYKCSECDKCFTKKFSLRIHQR 428

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
erm	NP_001259891.2	COG5048	<295..461	CDD:227381	63/149 (42%)
		C2H2 Zn finger	320..340	CDD:275368	7/19 (37%)
		zf-H2C2_2	332..357	CDD:290200	11/24 (46%)
		zf-C2H2	346..368	CDD:278523	7/21 (33%)
		C2H2 Zn finger	348..368	CDD:275368	7/19 (37%)
		zf-H2C2_2	363..385	CDD:290200	11/21 (52%)
		C2H2 Zn finger	376..396	CDD:275368	9/19 (47%)
		zf-H2C2_2	389..413	CDD:290200	13/23 (57%)
		C2H2 Zn finger	404..424	CDD:275368	6/19 (32%)
		zf-H2C2_2	416..441	CDD:290200	11/24 (46%)
		C2H2 Zn finger	432..452	CDD:275368	6/19 (32%)
		C2H2 Zn finger	460..478	CDD:275368	7/17 (41%)
Zfp992	NP_001078991.1	KRAB	13..>55	CDD:214630
		KRAB	13..52	CDD:279668
		C2H2 Zn finger	186..206	CDD:275368
		C2H2 Zn finger	218..234	CDD:275368
		C2H2 Zn finger	242..262	CDD:275368
		zf-H2C2_2	254..279	CDD:290200	8/17 (47%)
		COG5048	266..>550	CDD:227381	70/165 (42%)
		C2H2 Zn finger	270..290	CDD:275368	7/19 (37%)
		zf-H2C2_2	282..306	CDD:290200	10/23 (43%)
		C2H2 Zn finger	298..318	CDD:275368	7/19 (37%)
		zf-H2C2_2	310..335	CDD:290200	12/24 (50%)
		C2H2 Zn finger	326..346	CDD:275368	9/19 (47%)
		zf-H2C2_2	338..362	CDD:290200	12/23 (52%)
		C2H2 Zn finger	354..374	CDD:275368	6/19 (32%)
		zf-H2C2_2	366..390	CDD:290200	10/23 (43%)
		C2H2 Zn finger	382..402	CDD:275368	6/19 (32%)
		zf-H2C2_2	394..418	CDD:290200	9/23 (39%)
		C2H2 Zn finger	410..430	CDD:275368	8/19 (42%)
		zf-H2C2_2	422..446	CDD:290200	3/7 (43%)
		C2H2 Zn finger	438..458	CDD:275368
		zf-H2C2_2	450..474	CDD:290200
		C2H2 Zn finger	466..486	CDD:275368
		zf-H2C2_2	479..502	CDD:290200
		C2H2 Zn finger	494..514	CDD:275368
		zf-H2C2_2	506..530	CDD:290200
		C2H2 Zn finger	522..542	CDD:275368
		zf-H2C2_2	535..558	CDD:290200
		C2H2 Zn finger	550..566	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000