DRSC/TRiP Functional Genomics Resources

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Protein Alignment erm and sqz

DIOPT Version :9

Sequence 1:NP_001259891.2 Gene:erm / 326152 FlyBaseID:FBgn0031375 Length:698 Species:Drosophila melanogaster
Sequence 2:NP_524403.1 Gene:sqz / 42300 FlyBaseID:FBgn0010768 Length:535 Species:Drosophila melanogaster


Alignment Length:488 Identity:130/488 - (26%)
Similarity:188/488 - (38%) Gaps:106/488 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly   211 HHSQSLRRNLGHPLAAAAAVAAVAQSQAVPNLQ--HTLEKSPVAQRTAQSSGLQANLKRKRSPQD 273
            |..|..:::|.||          .|.|..|.|:  ::...||......|......|    ||   
  Fly    77 HPDQQQQQHLHHP----------QQQQHPPQLKVSYSAPNSPPTPHEQQEQKYDPN----RS--- 124

  Fly   274 QGEVTPPPASTATSATGARSRSPSPQGSIEDSSPGSASGGKPKTFSCLECGKVF-NAHYNLTRHM 337
                  ||....:||:|:.|...||:   |:|..|.....||  :.|..|.|.| |:.| |::|.
  Fly   125 ------PPRQQMSSASGSGSNGSSPE---EESRRGDGDQAKP--YKCGSCSKSFANSSY-LSQHT 177

  Fly   338 PVHTGARPFVCKVCGKGFRQASTLCRHKIIHTSEKPHKCQTCGKAFNRSSTLNTHSRIHAGYKPF 402
            .:|.|.:|:.|::|.:.|.|.|.|.:|...||.:||:||:                  |||    
  Fly   178 RIHLGIKPYRCEICQRKFTQLSHLQQHIRTHTGDKPYKCR------------------HAG---- 220

  Fly   403 VCEYCGKGFHQKGNYKNHKLTHSGEKAYKCNICNKAFHQVYNLTFHMHTHNDK---KPYTCRVCA 464
                |.|.|.|..|.::|...|..:|.:|||.|.|.|.....|..|:..|.|.   |.:.|.:|.
  Fly   221 ----CPKAFSQLSNLQSHSRCHQTDKPFKCNSCYKCFSDEMTLLEHIPKHKDSKHLKTHICNLCG 281

  Fly   465 KGFCRNFDLKKHMRKLHEIGGDLDDLDMPPTYDRRREYT------RREPLASGYG-----QAS-- 516
            |.:.:...|:||::|..|           ....::..:|      ::...|||.|     ||.  
  Fly   282 KSYTQETYLQKHLQKHAE-----------KAEKQQHRHTAQVAAHQQHVPASGIGLNLQRQAMND 335

  Fly   517 ------GQLTPDSSSGSMSPPINVTTPPLSSGETSNPAWPRSAVSQYPPGGFHHQ-LGVAP---- 570
                  .::..||::.|::..|....|........|.|..:....|......||| |...|    
  Fly   336 VNAAYWAKMGADSAAASLAEAIQQQLPQAGGQPYGNFASLQQQHQQQQQELLHHQRLADTPGHSH 400

  Fly   571 -PHDYPSGSAFL--QLQPQQPHPQSQQHHQQQQRLSETFIAKVFXQRYYAESLNSSTGSTSTTSS 632
             ||:..:|...:  |..||. |.|.||..||||:      |:...|..:..|......:.:..|:
  Fly   401 SPHEEAAGEDLVLRQSTPQH-HLQQQQQQQQQQQ------AQQQQQAQHQPSPGPGNSAFTPLSA 458

  Fly   633 TVTTTTTAISSMATSRSDLLIDXLQFVAAAAAA 665
            ||..............|.......|..||||||
  Fly   459 TVAPPPHLQQHRGPPGSAAAYLYQQNAAAAAAA 491

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ermNP_001259891.2 COG5048 <295..461 CDD:227381 53/169 (31%)
C2H2 Zn finger 320..340 CDD:275368 8/20 (40%)
zf-H2C2_2 332..357 CDD:290200 8/24 (33%)
zf-C2H2 346..368 CDD:278523 7/21 (33%)
C2H2 Zn finger 348..368 CDD:275368 7/19 (37%)
zf-H2C2_2 363..385 CDD:290200 7/21 (33%)
C2H2 Zn finger 376..396 CDD:275368 1/19 (5%)
zf-H2C2_2 389..413 CDD:290200 6/23 (26%)
C2H2 Zn finger 404..424 CDD:275368 6/19 (32%)
zf-H2C2_2 416..441 CDD:290200 10/24 (42%)
C2H2 Zn finger 432..452 CDD:275368 7/19 (37%)
C2H2 Zn finger 460..478 CDD:275368 6/17 (35%)
sqzNP_524403.1 C2H2 Zn finger 160..180 CDD:275368 8/20 (40%)
zf-H2C2_2 172..197 CDD:290200 9/25 (36%)
zf-C2H2 186..208 CDD:278523 7/21 (33%)
C2H2 Zn finger 188..208 CDD:275368 7/19 (37%)
zf-C2H2_8 191..271 CDD:292531 33/105 (31%)
zf-H2C2_2 200..227 CDD:290200 14/52 (27%)
C2H2 Zn finger 216..238 CDD:275368 10/47 (21%)
C2H2 Zn finger 246..266 CDD:275368 7/19 (37%)
C2H2 Zn finger 277..297 CDD:275368 6/19 (32%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 57 1.000 Inparanoid score I4043
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
11.050

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