Protein Alignment erm and Zbtb49

DIOPT Version :10

• Sequence 1: NP_001259891.2
• Gene: erm / 326152
• FlyBaseID: FBgn0031375
• Length: 698
• Species: Drosophila melanogaster
• Sequence 2: NP_001381611.1
• Gene: Zbtb49 / 305428
• RGDID: 1306733
• Length: 758
• Species: Rattus norvegicus
• Alignment Length: 708
• Identity: 175/708 - (24%)
• Similarity: 264/708 - (37%)
• Gaps: 195/708 - (27%)

  Fly     3 YFSPRGMQPCSPAGEIA--------MMPPS---------KSPVMESAASEQNPAQQ--------- 41
            ::.|..:|.|...|..|        ..||:         ..|...|.:..:.|.:|
  Rat   151 HYPPHSLQDCPMEGPRAKDVSRGNPRAPPADFGRPTGEGSKPAAASGSCPEAPRKQPNCYYKLRT 215

  Fly    42 --SQQQDEQSAKRACPLKFSIAKIMEPDHRPSQVPPPQPAPVSFATND-DDEDEDPEIDADSERS 103
              |:|..:|:   ||               ||.||..:..|...|:.| ...|..|.::..:
  Rat   216 LYSKQYYKQT---AC---------------PSPVPATEQPPTPRASTDLAAADSQPPVEGRA--- 259

  Fly   104 CSPIEVISLDQSPSTVNYDSAFKKYVPGPCSGATSSVASPPSTAAVQQFVSSRHQELLSQYPLLY 168
                   .:.:||..:                 .|:|.:||    |:........:.|||.|
  Rat   260 -------GVPESPEHL-----------------ASTVVAPP----VRSSGIDSEADTLSQPP--- 293

  Fly   169 YAPNQLMCAAAAAQYAALTAQQQSLASAAHLSSFTASLNASLHHSQSLRRNLGHPLAAAAAVAAV 233
                               |:|..|..|.||...      :...||.......||.:....|..
  Rat   294 -------------------AKQMRLKKAMHLKKL------NFLKSQQSAECTSHPQSDNVLVRG- 332

  Fly   234 AQSQAVPNLQHTLEKSPVAQRTAQSSGLQANLKRKR---SPQDQGEVTPP--PASTATSATGARS 293
                         |:|...:...:.:|.|....:.|   .|:...||..|  |||....:...:|
  Rat   333 -------------EESAAKEDAGERAGSQTTEDKGREELGPESSREVEMPGAPASWEDPSQALQS 384

  Fly   294 R---------SPSPQGSIEDSSPGSASGGKPKTFSCLECGKVFNAHYNLTRHMPVHTGARPFVCK 349
            :         .|....|..:....|.:|.||  |.|..|||.|:...||..|:..|:|.:|::|:
  Rat   385 QKQYACELCGKPFKHPSNLELHKRSHTGEKP--FECNICGKHFSQAGNLQTHLRRHSGEKPYICE 447

  Fly   350 VCGKGFRQASTLCRHKIIHTSEKPHKCQTCGKAFNRSSTLNTHSRIHAGYKPFVCEYCGKGFHQK 414
            :|||.|..:..:.||.|||:.||||.|.|||:.|:..|.|..|.:.|...|.|.|:.|||.|:.:
  Rat   448 ICGKRFAASGDVQRHIIIHSGEKPHLCDTCGRGFSNFSNLKEHKKTHTADKVFTCDECGKSFNMQ 512

  Fly   415 GNYKNHKLTHSGEKAYKCNICNKAFHQVYNLTFHMHTHNDKKPYTCRVCAKGFCRNFDLKKHMRK 479
            .....|::.|:||:.|.|..|.|.|....:|..|:.||..:|||:|.:|:|.|.|:..|::| ::
  Rat   513 RKLVKHRVRHTGERPYSCPACGKCFGGSGDLRRHVRTHTGEKPYSCEICSKCFTRSAVLRRH-KR 576

  Fly   480 LHEIGGDLDDLDMPPTYDRRREYTRREPLASGYGQA--SGQLTPDSSSGSMSPPINVTTPPLSSG 542
            :|                 .|...|...:.....||  :..|....||.|.|..::||..|:|
  Rat   577 MH-----------------GRAEARSPVVLDELSQAIETSDLDRSQSSDSFSQDVSVTLMPVS-- 622

  Fly   543 ETSNPAWP-RSAVSQYPPGGFH-HQLGVAPPHDYPSGSAFLQLQPQQPHPQSQQHHQQQQRLSET 605
             ...||.| .|:|:     ||. |..|           ::.:|: ...||.|.. .|.:..|..|
  Rat   623 -VKLPAHPVESSVA-----GFDGHCTG-----------SYCKLR-SMLHPPSMS-DQDKLSLEPT 668

  Fly   606 FIAK-----VFXQRYYAESLNSSTG-------STSTTSSTVTT----TTTAISSMATS 647
            .:||     ...|.|....::||.|       .|:.:.|::.|    .|..:.|.|.|
  Rat   669 KVAKPPELHSQPQAYTYSDVDSSAGVQQPQADGTAVSRSSLATLDNHCTEPLGSRAPS 726

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
erm	NP_001259891.2	COG5048	<295..461	CDD:227381	64/165 (39%)
		C2H2 Zn finger	320..340	CDD:275368	8/19 (42%)
		C2H2 Zn finger	348..368	CDD:275368	8/19 (42%)
		zf-H2C2_2	363..385	CDD:463886	14/21 (67%)
		C2H2 Zn finger	376..396	CDD:275368	8/19 (42%)
		C2H2 Zn finger	404..424	CDD:275368	6/19 (32%)
		C2H2 Zn finger	432..452	CDD:275368	6/19 (32%)
		C2H2 Zn finger	460..478	CDD:275368	7/17 (41%)
Zbtb49	NP_001381611.1	BTB_POZ_ZBTB49	7..118	CDD:349542
		PHA03247	<121..300	CDD:223021	38/219 (17%)
		zf-C2H2	388..410	CDD:395048	2/21 (10%)
		C2H2 Zn finger	390..410	CDD:275368	2/19 (11%)
		COG5048	<400..578	CDD:227381	70/180 (39%)
		C2H2 Zn finger	418..438	CDD:275368	8/19 (42%)
		C2H2 Zn finger	446..466	CDD:275368	8/19 (42%)
		C2H2 Zn finger	474..494	CDD:275368	8/19 (42%)
		C2H2 Zn finger	502..522	CDD:275368	6/19 (32%)
		C2H2 Zn finger	530..550	CDD:275368	6/19 (32%)
		C2H2 Zn finger	558..578	CDD:275368	7/20 (35%)